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1.

Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia.

Guimarães, Patrícia O; Quirk, Daniel; Furtado, Remo H; Maia, Lilia N; Saraiva, José F; Antunes, Murillo O; Kalil Filho, Roberto; Junior, Vagner M; Soeiro, Alexandre M; Tognon, Alexandre P; Veiga, Viviane C; Martins, Priscilla A; Moia, Diogo D F; Sampaio, Bruna S; Assis, Silvia R L; Soares, Ronaldo V P; Piano, Luciana P A; Castilho, Kleber; Momesso, Roberta G R A P; Monfardini, Frederico; Guimarães, Helio P; Ponce de Leon, Dario; Dulcine, Majori; Pinheiro, Marcia R T; Gunay, Levent M; Deuring, J Jasper; Rizzo, Luiz V; Koncz, Tamas; Berwanger, Otavio.

N Engl J Med; 385(5): 406-415, 2021 07 29.

Artículo en Inglés | MEDLINE | ID: mdl-34133856

2.

Angiotensin Receptor-Neprilysin Inhibition in Acute Myocardial Infarction.

Pfeffer, Marc A; Claggett, Brian; Lewis, Eldrin F; Granger, Christopher B; Køber, Lars; Maggioni, Aldo P; Mann, Douglas L; McMurray, John J V; Rouleau, Jean-Lucien; Solomon, Scott D; Steg, Philippe G; Berwanger, Otavio; Cikes, Maja; De Pasquale, Carmine G; East, Cara; Fernandez, Alberto; Jering, Karola; Landmesser, Ulf; Mehran, Roxana; Merkely, Béla; Vaghaiwalla Mody, Freny; Petrie, Mark C; Petrov, Ivo; Schou, Morten; Senni, Michele; Sim, David; van der Meer, Peter; Lefkowitz, Martin; Zhou, Yinong; Gong, Jianjian; Braunwald, Eugene.

N Engl J Med; 385(20): 1845-1855, 2021 11 11.

Artículo en Inglés | MEDLINE | ID: mdl-34758252

3.

One-year Outcomes after Discharge from Noncardiac Surgery and Association between Predischarge Complications and Death after Discharge: Analysis of the VISION Prospective Cohort Study.

Roshanov, Pavel S; Chan, Matthew T V; Borges, Flavia K; Conen, David; Wang, C Y; Xavier, Denis; Berwanger, Otavio; Marcucci, Maura; Sessler, Daniel I; Szczeklik, Wojciech; Spence, Jessica; Alonso-Coello, Pablo; Fernández, Carmen; Pearse, Rupert M; Malaga, German; Garg, Amit X; Srinathan, Sadeesh K; Jacka, Michael J; Tandon, Vikas; McGillion, Michael; Popova, Ekaterine; Sigamani, Alben; Abraham, Valsa; Biccard, Bruce M; Villar, Juan Carlos; Chow, Clara K; Polanczyk, Carísi A; Tiboni, Maria; Whitlock, Richard; Ackland, Gareth L; Panju, Mohamed; Lamy, André; Sapsford, Robert; Williams, Colin; Wu, William Ka Kei; Cortés, Olga L; MacNeil, S Danielle; Patel, Ameen; Belley-Côté, Emilie P; Ofori, Sandra; McIntyre, William F; Leong, Darryl P; Heels-Ansdell, Diane; Gregus, Krysten; Devereaux, P J.

Anesthesiology; 140(1): 8-24, 2024 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-37713506

4.

Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial.

Hess, Connie N; Hsia, Judith; Carroll, Ian A; Nehler, Mark R; Ruf, Wolfram; Morrow, David A; Nicolau, Jose C; Berwanger, Otavio; Szarek, Michael; Capell, Warren H; Johri, Shilpa; Pursley, Michael S; Gupta, Ryan; Meehan, Patrick S; Franchi, Francesco; Effron, Mark B; Marshall, Debra; Graybill, Christopher A; Huebler, Sophia P; Keuer, Thomas; Bristow, Michael R; Bonaca, Marc P.

Arterioscler Thromb Vasc Biol; 43(8): 1572-1582, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37381988

5.

Predictors of bleeding and thrombotic events among patients admitted to the hospital with COVID-19 and elevated D-dimer: insights from the ACTION randomized clinical trial.

de Barros E Silva, Pedro Gabriel Melo; Furtado, Remo H M; de Alcântara Chaud, Mariana Silveira; Macedo, Ariane Vieira Scarlatelli; Bronhara, Bruna; Damiani, Lucas Petri; Barbosa, Lilian Mazza; Suiama, Mayra Akimi; Ramacciotti, Eduardo; de Aquino Martins, Priscilla; de Oliveira, Aryadne Lyrio; Nunes, Vinicius Santana; Ritt, Luiz Eduardo Fonteles; Rocha, Ana Thereza; Tramujas, Lucas; Santos, Sueli V; Diaz, Dario Rafael Abregu; Viana, Lorena Souza; Melro, Lívia Maria Garcia; Figueiredo, Estêvão Lanna; Neuenschwander, Fernando Carvalho; Dracoulakis, Marianna Deway Andrade; Lima, Rodolfo Godinho Souza Dourado; de Souza Dantas, Vicente Cés; Fernandes, Anne Cristine Silva; Gebara, Otávio Celso Eluf; Hernandes, Mauro Esteves; Queiroz, Diego Aparecido Rios; Veiga, Viviane C; Canesin, Manoel Fernandes; de Faria, Leonardo Meira; Feitosa-Filho, Gilson Soares; Gazzana, Marcelo Basso; Liporace, Idelzuíta Leandro; de Oliveira Twardowsky, Aline; Maia, Lilia Nigro; Machado, Flávia Ribeiro; de Matos Soeiro, Alexandre; Conceição-Souza, Germano Emílio; Armaganijan, Luciana; Guimarães, Patrícia O; Rosa, Regis G; Azevedo, Luciano C P; Alexander, John H; Avezum, Alvaro; Berwanger, Otávio; Cavalcanti, Alexandre B; Lopes, Renato D.

J Thromb Thrombolysis; 2024 May 18.

Artículo en Inglés | MEDLINE | ID: mdl-38762708

6.

The Effects of Angiotensin Receptor-Neprilysin Inhibition on Major Coronary Events in Patients With Acute Myocardial Infarction: Insights From the PARADISE-MI Trial.

Mehran, Roxana; Steg, Philippe Gabriel; Pfeffer, Marc A; Jering, Karola; Claggett, Brian; Lewis, Eldrin F; Granger, Christopher; Køber, Lars; Maggioni, Aldo; Mann, Douglas L; McMurray, John J V; Rouleau, Jean-Lucien; Solomon, Scott D; Ducrocq, Gregory; Berwanger, Otavio; De Pasquale, Carmine G; Landmesser, Ulf; Petrie, Mark; Leng, David Sim Kheng; van der Meer, Peter; Lefkowitz, Martin; Zhou, Yinong; Braunwald, Eugene.

Circulation; 146(23): 1749-1757, 2022 12 06.

Artículo en Inglés | MEDLINE | ID: mdl-36321459

7.

Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve.

Guimarães, Helio P; Lopes, Renato D; de Barros E Silva, Pedro G M; Liporace, Idelzuita L; Sampaio, Roney O; Tarasoutchi, Flávio; Hoffmann-Filho, Conrado R; de Lemos Soares Patriota, Rodrigo; Leiria, Tiago L L; Lamprea, Diana; Precoma, Dalton B; Atik, Fernando A; Silveira, Fabio S; Farias, Fabio R; Barreto, Diogo O; Almeida, Adail P; Zilli, Alexandre C; de Souza Neto, João D; Cavalcante, Margaret A; Figueira, Fernando A M S; Kojima, Flávia C S; Damiani, Lucas; Santos, Renato H N; Valeis, Nanci; Campos, Viviane B; Saraiva, Jose F K; Fonseca, Francisco H; Pinto, Ibraim M; Magalhães, Carlos C; Ferreira, Joao F M; Alexander, John H; Pavanello, Ricardo; Cavalcanti, Alexandre B; Berwanger, Otavio.

N Engl J Med; 383(22): 2117-2126, 2020 11 26.

Artículo en Inglés | MEDLINE | ID: mdl-33196155

8.

Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.

Cavalcanti, Alexandre B; Zampieri, Fernando G; Rosa, Regis G; Azevedo, Luciano C P; Veiga, Viviane C; Avezum, Alvaro; Damiani, Lucas P; Marcadenti, Aline; Kawano-Dourado, Letícia; Lisboa, Thiago; Junqueira, Debora L M; de Barros E Silva, Pedro G M; Tramujas, Lucas; Abreu-Silva, Erlon O; Laranjeira, Ligia N; Soares, Aline T; Echenique, Leandro S; Pereira, Adriano J; Freitas, Flávio G R; Gebara, Otávio C E; Dantas, Vicente C S; Furtado, Remo H M; Milan, Eveline P; Golin, Nicole A; Cardoso, Fábio F; Maia, Israel S; Hoffmann Filho, Conrado R; Kormann, Adrian P M; Amazonas, Roberto B; Bocchi de Oliveira, Monalisa F; Serpa-Neto, Ary; Falavigna, Maicon; Lopes, Renato D; Machado, Flávia R; Berwanger, Otavio.

N Engl J Med; 383(21): 2041-2052, 2020 11 19.

Artículo en Inglés | MEDLINE | ID: mdl-32706953

9.

The effects of canagliflozin in type 2 diabetes in subgroups defined by population-specific body mass index: Insights from the CANVAS Program and CREDENCE trial.

Yu, Jie; Sweeting, Arianne N; Gianacas, Chris; Houston, Lauren; Lee, Vivian; Fletcher, Robert A; Perkovic, Vlado; Li, Qiang; Neuen, Brendon L; Berwanger, Otavio; Heerspink, Hiddo J L; de Zeeuw, Dick; Arnott, Clare.

Diabetes Obes Metab; 25(12): 3724-3735, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-37671609

10.

Influenza vaccination strategy in acute coronary syndromes: the VIP-ACS trial.

Fonseca, Henrique Andrade R; Furtado, Remo Holanda M; Zimerman, André; Lemos, Pedro A; Franken, Marcelo; Monfardini, Frederico; Pedrosa, Rodrigo P; Patriota, Rodrigo de Lemos S; Passos, Luiz Carlos S; Dall'Orto, Frederico Toledo C; Hoffmann Filho, Conrado R; Nascimento, Bruno Ramos; Baldissera, Felipe A; Pereira, Cesar Augusto C; Caramori, Paulo Ricardo A; de Andrade, Pedro Beraldo; Esteves, Carlos; Salim, Elke Ferreira; da Silva, Jefferson Henrique; Pedro, Izabela Chave; Silva, Mariana Castaldi R; de Pedri, Ewerton Hernandes; Carioca, Ana Carla R D; de Piano, Luciana Pereira A; Albuquerque, Camila Santos N; Moia, Diogo D F; Momesso, Roberta Grazzielli R A P; Machado, Felipe P; Damiani, Lucas P; Soares, Ronaldo Vicente P; Schettino, Guilherme P; Rizzo, Luiz V; Nicolau, José Carlos; Berwanger, Otávio.

Eur Heart J; 43(41): 4378-4388, 2022 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-36030400

11.

Apixaban or Vitamin K Antagonists and Aspirin or Placebo According to Kidney Function in Patients With Atrial Fibrillation After Acute Coronary Syndrome or Percutaneous Coronary Intervention: Insights From the AUGUSTUS Trial.

Hijazi, Ziad; Alexander, John H; Li, Zhuokai; Wojdyla, Daniel M; Mehran, Roxana; Granger, Christopher B; Parkhomenko, Alexander; Bahit, M Cecilia; Windecker, Stephan; Aronson, Ronald; Berwanger, Otavio; Halvorsen, Sigrun; de Waha-Thiele, Suzanne; Sinnaeve, Peter; Darius, Harald; Storey, Robert F; Lopes, Renato D.

Circulation; 143(12): 1215-1223, 2021 03 23.

Artículo en Inglés | MEDLINE | ID: mdl-33461308

12.

Digital Health-Enabled Clinical Trials in Stroke: Ready for Prime Time?

Berwanger, Otavio; Machline-Carrion, M Julia.

Stroke; 53(9): 2967-2975, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35770670

13.

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.

Lopes, Renato D; de Barros E Silva, Pedro Gabriel Melo; Furtado, Remo H M; Macedo, Ariane Vieira Scarlatelli; Bronhara, Bruna; Damiani, Lucas Petri; Barbosa, Lilian Mazza; de Aveiro Morata, Júlia; Ramacciotti, Eduardo; de Aquino Martins, Priscilla; de Oliveira, Aryadne Lyrio; Nunes, Vinicius Santana; Ritt, Luiz Eduardo Fonteles; Rocha, Ana Thereza; Tramujas, Lucas; Santos, Sueli V; Diaz, Dario Rafael Abregu; Viana, Lorena Souza; Melro, Lívia Maria Garcia; de Alcântara Chaud, Mariana Silveira; Figueiredo, Estêvão Lanna; Neuenschwander, Fernando Carvalho; Dracoulakis, Marianna Deway Andrade; Lima, Rodolfo Godinho Souza Dourado; de Souza Dantas, Vicente Cés; Fernandes, Anne Cristine Silva; Gebara, Otávio Celso Eluf; Hernandes, Mauro Esteves; Queiroz, Diego Aparecido Rios; Veiga, Viviane C; Canesin, Manoel Fernandes; de Faria, Leonardo Meira; Feitosa-Filho, Gilson Soares; Gazzana, Marcelo Basso; Liporace, Idelzuíta Leandro; de Oliveira Twardowsky, Aline; Maia, Lilia Nigro; Machado, Flávia Ribeiro; de Matos Soeiro, Alexandre; Conceição-Souza, Germano Emílio; Armaganijan, Luciana; Guimarães, Patrícia O; Rosa, Regis G; Azevedo, Luciano C P; Alexander, John H; Avezum, Alvaro; Cavalcanti, Alexandre B; Berwanger, Otavio.

Lancet; 397(10291): 2253-2263, 2021 06 12.

Artículo en Inglés | MEDLINE | ID: mdl-34097856

14.

Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation.

Lopes, Renato D; Heizer, Gretchen; Aronson, Ronald; Vora, Amit N; Massaro, Tyler; Mehran, Roxana; Goodman, Shaun G; Windecker, Stephan; Darius, Harald; Li, Jia; Averkov, Oleg; Bahit, M Cecilia; Berwanger, Otavio; Budaj, Andrzej; Hijazi, Ziad; Parkhomenko, Alexander; Sinnaeve, Peter; Storey, Robert F; Thiele, Holger; Vinereanu, Dragos; Granger, Christopher B; Alexander, John H.

N Engl J Med; 380(16): 1509-1524, 2019 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-30883055

15.

Morphine and clinical outcomes in patients with ST segment elevation myocardial infarction treated with fibrinolytic and antiplatelet therapy: Insights from the TREAT trial.

Cantor, Warren J; Tan, Mary; Berwanger, Otavio; Lavi, Shahar; White, Harvey D; Nicolau, Jose C; Dehghani, Payam; Tajer, Carlos D; Lopes, Renato D; Moia, Diogo D F; Nicholls, Stephen J; Parkhomenko, Alexander; Averkov, Oleg; Brass, Neil; Lutchmedial, Sohrab; Malaga, Germán; Damiani, Lucas P; Piegas, Leopoldo S; Granger, Christopher B; Goodman, Shaun G.

Am Heart J; 251: 1-12, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35533724

16.

Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial.

Furtado, Remo H M; Berwanger, Otavio; Fonseca, Henrique A; Corrêa, Thiago D; Ferraz, Leonardo R; Lapa, Maura G; Zampieri, Fernando G; Veiga, Viviane C; Azevedo, Luciano C P; Rosa, Regis G; Lopes, Renato D; Avezum, Alvaro; Manoel, Airton L O; Piza, Felipe M T; Martins, Priscilla A; Lisboa, Thiago C; Pereira, Adriano J; Olivato, Guilherme B; Dantas, Vicente C S; Milan, Eveline P; Gebara, Otavio C E; Amazonas, Roberto B; Oliveira, Monalisa B; Soares, Ronaldo V P; Moia, Diogo D F; Piano, Luciana P A; Castilho, Kleber; Momesso, Roberta G R A P; Schettino, Guilherme P P; Rizzo, Luiz Vicente; Neto, Ary Serpa; Machado, Flávia R; Cavalcanti, Alexandre B.

Lancet; 396(10256): 959-967, 2020 10 03.

Artículo en Inglés | MEDLINE | ID: mdl-32896292

17.

Randomized clinical trial to evaluate a routine full anticoagulation Strategy in Patients with Coronavirus Infection (SARS-CoV2) admitted to hospital: Rationale and design of the ACTION (AntiCoagulaTlon cOroNavirus)-Coalition IV trial.

Lopes, Renato D; de Barros E Silva, Pedro Gabriel Melo; Furtado, Remo H M; Macedo, Ariane Vieira Scarlatelli; Ramacciotti, Eduardo; Damini, Lucas Petri; Bronhara, Bruna; Cavalcanti, Alexandre B; Rosa, Regis G; Azevedo, Luciano C P; Veiga, Viviane C; Machado, Flávia R; Ritt, Luiz Eduardo; Martins, Priscilla de Aquino; Alexander, John H; Avezum, Alvaro; Berwanger, Otavio.

Am Heart J; 238: 1-11, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-33891907

18.

A randomized clinical trial to evaluate the efficacy and safety of rivaroxaban in patients with bioprosthetic mitral valve and atrial fibrillation or flutter: Rationale and design of the RIVER trial.

Guimarães, Helio P; de Barros E Silva, Pedro G M; Liporace, Idelzuita L; Sampaio, Roney O; Tarasoutchi, Flávio; Paixão, Milena; Hoffmann-Filho, Conrado R; Patriota, Rodrigo; Leiria, Tiago L L; Lamprea, Diana; Precoma, Dalton B; Atik, Fernando A; Silveira, Fabio S; Farias, Fabio R; Barreto, Diogo O; Almeida, Adail P; Zilli, Alexandre C; de Souza Neto, João D; Cavalcante, Margaret A; Figueira, Fernando A M S; Junior, Roque A; Moisés, Valdir A; Mesas, Cezar E; Ardito, Roberto V; Kalil, Paulo S A; Paiva, Maria S M O; Maldonado, Jaime G A; de Lima, Carlos E B; D'Oliveira Vieira, Ricardo; Laranjeira, Ligia; Kojima, Flávia; Damiani, Lucas; Nakagawa, Renato H; Dos Santos, Juliana R Y; Sampaio, Bruna S; Campos, Viviane B; Saraiva, Jose F K; Fonseca, Francisco H; Pinto, Ibraim M; Magalhães, Carlos C; Ferreira, Joao F M; Lopes, Renato D; Pavanello, Ricardo; Cavalcanti, Alexandre B; Berwanger, Otavio.

Am Heart J; 231: 128-136, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33045224

19.

Three-year effects of bariatric surgery on obstructive sleep apnea in patients with obesity grade 1 and 2: a sub-analysis of the GATEWAY trial.

Furlan, Sofia F; Drager, Luciano F; Santos, Renato Nakagawa; Damiani, Lucas P; Bersch-Ferreira, Angela Cristine; Miranda, Tamiris A; Machado, Rachel Helena V; Santucci, Eliana V; Bortolotto, Luiz A; Lorenzi-Filho, Geraldo; Berwanger, Otavio; Cavalcanti, Alexandre B; Schiavon, Carlos A.

Int J Obes (Lond); 45(4): 914-917, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33589771

20.

Effects of dapagliflozin on prevention of major clinical events and recovery in patients with respiratory failure because of COVID-19: Design and rationale for the DARE-19 study.

Kosiborod, Mikhail; Berwanger, Otavio; Koch, Gary G; Martinez, Felipe; Mukhtar, Omar; Verma, Subodh; Chopra, Vijay; Javaheri, Ali; Ambery, Philip; Gasparyan, Samvel B; Buenconsejo, Joan; Sjöström, C David; Langkilde, Anna Maria; Oscarsson, Jan; Esterline, Russell.

Diabetes Obes Metab; 23(4): 886-896, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33319454

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