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1.
Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).
Bioorg Med Chem;
24(4): 521-44, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26762835
2.
Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.
Bioorg Med Chem;
16(7): 3907-16, 2008 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18272371
3.
Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).
J Med Chem;
57(3): 578-99, 2014 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24417566
4.
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
J Med Chem;
56(13): 5562-86, 2013 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23750455
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