Severe Rhabdomyolysis in a Pediatric Patient after Coxsackie B Virus Infection without Acute Renal Failure: A Case Report.

Rhabdomyolysis is a condition resulting from the breakdown of skeletal muscle fibers with leakage of muscle enzymes into the circulation. The degraded muscle components in the circulation can lead to lethal complications as acute renal failure (ARF). In younger children, viral infections tend to be the major cause while trauma and exercise are the important ones in adolescents. Several viruses such as influenza A & B, parainfluenza and coxsackie have been implicated in causing rhabdomyolysis. We report a case of a 14-year-old girl with severe rhabdomyolysis after recent Coxsackie B infection without acute renal failure.

Klippel-Trenaunay-Weber Syndrome with Kasabach-Merritt Coagulopathy and Hydronephrosis.

BACKGROUND: Klippel-Trenaunay-Weber Syndrome is a rare syndrome, consisting of vascular malformation of blood and lymph vessels. CASE CHARACTERISTICS: A newborn female with respiratory distress from birth, and having vascular malformation involving left thigh. OBSERVATION: The neonate also had hydronephrosis and developed complication of Kasabach Merritt syndrome. MESSAGE: Urogenital abnormalities can be present in Klippel-Trenaunay-Weber syndrome but hydronephrosis is rare. Mortality is high with development of Kasabach Merritt syndrome.

Autoimmune Lymphoproliferative Syndrome with Red Cell Aplasia.

Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare inherited disorder of abnormal lymphocyte apoptosis, leading to chronic lymphoproliferation. It presents as lymphadenopathy, hepatosplenomegaly and autoimmune phenomena. Pure red cell aplasia is characterized by normochromic normocytic anemia, reticulocytopenia, and absence of erythroblasts from a normal bone marrow. Only few lymphoproliferative disorders have been associated with erythroid aplasia. The authors are reporting a case of ALPS associated with red cell aplasia in a 7-y-old girl.