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1.
A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.
Nat Chem Biol;
11(12): 973-980, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26502155
2.
Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.
Bioorg Med Chem Lett;
25(7): 1597-602, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25736998
3.
Novel Methionine Aminopeptidase 2 Inhibitor M8891 Synergizes with VEGF Receptor Inhibitors to Inhibit Tumor Growth of Renal Cell Carcinoma Models.
Mol Cancer Ther;
23(2): 159-173, 2024 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37940144
4.
Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.
Biochem Biophys Res Commun;
431(2): 264-9, 2013 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-23313490
5.
Selective ATM inhibition augments radiation-induced inflammatory signaling and cancer cell death.
Aging (Albany NY);
15(2): 492-512, 2023 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36656721
6.
The Preclinical Pharmacology of Tepotinib-A Highly Selective MET Inhibitor with Activity in Tumors Harboring MET Alterations.
Mol Cancer Ther;
22(7): 833-843, 2023 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36999986
7.
Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors.
Mol Cancer Ther;
22(7): 859-872, 2023 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37079339
8.
Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.
J Biol Chem;
286(16): 14237-45, 2011 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-21357692
9.
Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2.
J Cell Biol;
177(1): 127-37, 2007 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-17403928
10.
A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies.
Mol Cancer Ther;
21(6): 859-870, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35405736
11.
DNA-PK Inhibitor Peposertib Amplifies Radiation-Induced Inflammatory Micronucleation and Enhances TGFß/PD-L1 Targeted Cancer Immunotherapy.
Mol Cancer Res;
20(4): 568-582, 2022 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34980594
12.
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.
Nat Med;
9(3): 352-5, 2003 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-12563315
13.
DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia.
Sci Rep;
11(1): 12148, 2021 06 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34108527
14.
Prediction of active human dose: learnings from 20 years of Merck KGaA experience, illustrated by case studies.
Drug Discov Today;
25(5): 909-919, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31981792
15.
DNA-PK Inhibitor, M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia.
Front Oncol;
10: 127, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32117773
16.
SHP2 Inhibition Influences Therapeutic Response to Tepotinib in Tumors with MET Alterations.
iScience;
23(12): 101832, 2020 Dec 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33305187
17.
Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics.
Mol Oncol;
14(6): 1185-1206, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32336009
18.
Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.
Mol Cancer Ther;
19(5): 1091-1101, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32220971
19.
Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814.
Mol Cancer Res;
17(12): 2457-2468, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31551253
20.
Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia.
Oncogene;
37(30): 4181-4196, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29717265