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1.
Artículo en Inglés | MEDLINE | ID: mdl-39225689

RESUMEN

ABSTRACT: The older generation TASER probes X26 and X2 have been shown to be capable of piercing the skull with their tips. With the introduction of the new TASER 7 and the far more powerful TASER 10, concerns have arisen as to whether these weapons might penetrate the skull more deeply and thus prove to be potentially lethal. For this reason, we tested the penetration capacity of these weapons on polyurethane-gelatine-buckskin head simulants at different firing distances. The striking speeds and striking angles were documented with a high-speed camera, and the piercing depths were recorded by computed tomography. None of the probes penetrated the skull, but their tips did; TASER 7 probe tips pierced up to 5.6 mm, whereas TASER 10 probe tips pierced up to 10.4 mm. The TASER 7 probes fared better with regard to penetration depth at shorter firing distances; on the other hand, the TASER 10 probes pierced more deeply at distances of 3 to 4 m, with their flight stability improving after the first 2 m. Our results imply that TASER 7 and TASER 10 probes are not to be expected to cause great harm or even death when striking the head.

2.
Forensic Sci Med Pathol ; 17(4): 726-729, 2021 12.
Artículo en Inglés | MEDLINE | ID: mdl-34106424

RESUMEN

The computed tomography (CT) scan of a 19-year-old man who died from an occipito-frontal gunshot wound presented an impressive radiating fracture line where the entire sagittal suture burst due to the high intracranial pressure that arose from a near-contact shot from a 9 mm bullet fired from a Glock 17 pistol. Photorealistic depictions of the radiating fracture lines along the cranial bones were created using three-dimensional reconstruction methods, such as the novel cinematic rendering technique that simulates the propagation and interaction of light when it passes through volumetric data. Since the brain had collapsed, depiction of soft tissue was insufficient on CT images. An additional magnetic resonance imaging (MRI) examination was performed, which enabled the diagnostic assessment of cerebral injuries.


Asunto(s)
Armas de Fuego , Heridas por Arma de Fuego , Adulto , Humanos , Imagenología Tridimensional , Masculino , Cráneo , Suturas , Tomografía Computarizada por Rayos X , Heridas por Arma de Fuego/diagnóstico por imagen , Adulto Joven
3.
Am J Forensic Med Pathol ; 41(2): 119-123, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32379075

RESUMEN

The use of postmortem computed tomography (CT) has been described in many articles concerning gunshot injuries. Postmortem magnetic resonance imaging (MRI) for better assessment of soft tissue injuries has also been mentioned in the literature, albeit much less often. The use of postmortem MRI for abdominal gunshot wounds has not been previously presented in the literature. The present case report describes the findings of an abdominal gunshot wound detected by postmortem CT and MRI, followed by an autopsy. The main imaging findings on CT were a hyperdense ring at the entrance wound, which indicated the muzzle imprint mark, a hyperdense region beneath the skin, which was suggestive of combustion residue, gas cavities surrounding the bullet path, which might be related to the temporary cavity, and a fracture of the 13th rib on the left. Magnetic resonance imaging provided a clear depiction of defects in the muscle tissue and peritoneal fat, as well as an injury to the left kidney and a large volume of blood in the abdominal cavity. Computed tomography combined with MRI provided a descriptive presentation of the intracorporeal trajectory noninvasively. Autopsy confirmed the radiologic findings but additionally revealed further relevant findings, which were not detected radiologically, such as a duodenal perforation. Autopsy also detected subendocardial hemorrhages and shock kidney, which were consistent with severe blood loss.The imaging findings and their interpretations are discussed in this case report, as well as the role of CT and MRI in the assessment of abdominal gunshot wounds compared with autopsy.


Asunto(s)
Traumatismos Abdominales/diagnóstico por imagen , Imagen por Resonancia Magnética , Tomografía Computarizada por Rayos X , Heridas por Arma de Fuego/diagnóstico por imagen , Traumatismos Abdominales/patología , Músculos Abdominales/diagnóstico por imagen , Músculos Abdominales/lesiones , Músculos Abdominales/patología , Glándulas Suprarrenales/lesiones , Glándulas Suprarrenales/patología , Duodeno/lesiones , Duodeno/patología , Patologia Forense , Humanos , Perforación Intestinal/patología , Riñón/diagnóstico por imagen , Riñón/lesiones , Riñón/patología , Hígado/lesiones , Hígado/patología , Masculino , Persona de Mediana Edad , Fracturas de las Costillas/diagnóstico por imagen , Fracturas de las Costillas/patología , Bazo/lesiones , Bazo/patología , Heridas por Arma de Fuego/patología
4.
Forensic Sci Med Pathol ; 16(2): 340-344, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-31873912

RESUMEN

We describe the case of a decomposed male cadaver found in an apartment who was transported to our institute for identification purposes. Computed tomography (CT) was performed to assess the possibility of a radiologic identification of the decedent (RadID) by dental implants or orthopedic implants. Surprisingly, the CT examination revealed seven spherical foreign bodies (diameter: 0.4 to 0.5 cm / 0.16 to 0.20 in) and one flat foreign body (diameter: 0.7 cm / 0.28 in; thickness 0.2 cm / 0.08 in) inside the cadaver. The foreign bodies were located extracranially in the soft tissue of the head (n = 1), the neck (n = 2), the abdomen (n = 2), the right upper arm (n = 1) and both thighs (n = 2) and were determined to be shot pellets according to their shape and high radiopacity. Immediately, the decedent was externally reexamined for entrance wounds according to the location of the shot pellets on CT. A thorough external examination revealed scarred entrance wounds on the head and neck. For the identification of the decedent, radiologic data from the renter of the apartment were requested from the municipal hospital. The radiology department provided a clinical CT scan of the abdomen of the suspected person, a 70-year-old man. An antemortem abdomen CT also demonstrated two shot pellets at the same location in the body. The decedent was radiologically identified by comparing the position of the retained shot pellets on antemortem and postmortem computed tomography. This case report presents a rare case of numerous retained shot pellets and the extraordinary RadID based on these retained shot pellets, which were only revealed because a postmortem CT scan was performed.


Asunto(s)
Identificación Biométrica/métodos , Cuerpos Extraños/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Heridas por Arma de Fuego/diagnóstico por imagen , Anciano , Humanos , Masculino
5.
Forensic Sci Med Pathol ; 16(2): 243-251, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32170495

RESUMEN

As it is unclear if and how long DNA evidence can persist on submerged skin, we examined the potential for recovery of touch DNA and blood stain DNA from skin samples immersed in different aquatic environments and temperatures for forensic purposes in this proof-of-concept study. We used pig skin, either smeared with human blood or held firmly for 30 s by two test-persons, before immersing it in either cold, room-temperature or warm water as well as in a stream and a pond for up to seven days prior to DNA testing. The samples were then typed at 16 STR loci. Cold water samples yielded the most promising results, as shown by the recovery of the full set of 16 reproducible STR loci from the touch DNA sample of one test-person after 7 days. For blood stains, we were able to recover all 16 reproducible STRs after 2 days. Room-temperature water and warm water yielded varying results for both blood stain DNA and touch DNA. For pond and stream samples, DNA recovery was possible only within two days. While the pond and stream samples were at relatively cold temperatures, DNA recovery may have been affected by the presence of water insects and snails in the pond and mud in the stream. Our findings show the potential of using immersed samples, particularly those immersed in cold water, as we could detect a complete DNA profile from blood stains and from touch DNA after several days. Our study opens the way for future in-depth studies, examining larger datasets and a wider range of conditions.


Asunto(s)
Manchas de Sangre , ADN/aislamiento & purificación , Inmersión , Piel/química , Tacto , Animales , Dermatoglifia del ADN , Genética Forense , Repeticiones de Microsatélite , Porcinos , Temperatura
6.
Forensic Sci Med Pathol ; 14(1): 85-94, 2018 03.
Artículo en Inglés | MEDLINE | ID: mdl-29435816

RESUMEN

Due to slowing or even inhibition of postmortem processes, freezing may make an estimation of the time-since-death very difficult. This is also true in previously frozen and subsequently thawed bodies. Knowledge of prior freezing is important, as it may lead to a different assessment of the time since death. Twelve pig heads were frozen at -20 °C, and 6 heads were either kept at room temperature (approximately 20 °C) or in a cooling cell (approximately 5 °C). The frozen brains and cadavers were thawed at either room temperature or in a cooling cell. All specimens underwent repeated CT and MRI scanning until the brains were sampled for histological examination. Two radiologists assessed the images and two pathologists reviewed the histological slides with regard to thawing artifacts and putrefaction. All raters were blinded regarding whether the samples had been frozen, for how long and how they had been thawed. Imaging revealed distinct, tiny bubble-like artifacts only in previously frozen specimens. Histology also revealed artifacts only seen in such cases, namely very distinct, columnar bubbles in the cerebral cortex. All raters successfully identified previously unfrozen brains (100% specificity) and nearly all previously frozen brains. Our results suggest that initial post-mortem imaging can be of enormous importance in everyday forensic practice by identifying possible cases of previous freezing - cases that would therefore warrant closer scrutiny and thus raise caution regarding the time of death.


Asunto(s)
Encéfalo/diagnóstico por imagen , Congelación , Imagen por Resonancia Magnética , Tomografía Computarizada Multidetector , Animales , Artefactos , Encéfalo/patología , Patologia Forense , Modelos Animales , Cambios Post Mortem , Porcinos , Temperatura de Transición
7.
Forensic Sci Med Pathol ; 14(1): 120-122, 2018 03.
Artículo en Inglés | MEDLINE | ID: mdl-29423777

RESUMEN

Suitcases or other containers are occasionally involved in forensic investigations. If there is a suspicion that human remains are hidden inside such a container, medico-legal examinations are required. However, these containers are occasionally locked. Forced opening of a locked suitcase or container may cause damage to its contents. Additionally, the safety of the investigator has to be considered as such containers may be booby-trapped or contain other hazardous material. An overview of the contents before opening is desirable in order to avoid the possibility of encountering a Pandora's box. In forensic medicine, an established approach to examine the inside of a body before opening at autopsy is postmortem computed tomography (CT). However, there may be a reluctance to use this approach for suitcases or containers with metallic components because of the assumption that severe metal artifacts will result in inadequate images. In this article, we present a forensic case in which a CT scan of a metallic suitcase was performed in order to examine its contents. Additionally, we performed an experimental scan of a conventional safe in order to determine if CT is able to reveal the contents of such a highly radiopaque storage box.


Asunto(s)
Huesos/diagnóstico por imagen , Tomografía Computarizada Multidetector , Animales , Artefactos , Perros
8.
Forensic Sci Med Pathol ; 14(1): 31-41, 2018 03.
Artículo en Inglés | MEDLINE | ID: mdl-29197948

RESUMEN

We examined the possibility of inflicting serious injuries with sharp objects in an experimental setting by throwing four sharp objects from different distances and with different throwing techniques. Using an overarm-handle (OA/H), overarm-blade (OA/B), underarm-handle (UA/H), underarm-blade (UA/B) and thrust (T/H) throwing technique, 10 adults (sex ratio 1:1) threw a chef's knife, a skinning knife, a paring knife and office scissors from 4 m and 2 m distance at synthetic abdomen models made of 10% gelatin covered with synthetic skin. The amount of hits and penetrations of the target and their penetration depth were noted, as was the rotation of the blade tip towards the target along its flight trajectory. The chef's knife injury/hit ratio was 0.167/4 m and 0.160/2 m; the skinning knife recorded an injury/hit ratio of 0.087/4 m and 0.153/2 m; the paring knife of 0.087/4 m and 0.113/2 m; and the scissors 0.087/4 m and 0.067/2 m. Mean penetration depths were as follows: the chef's knife: 4 m, 4.42 cm, 2 m, 3.41 cm; the skinning knife: 4 m, 4.19 cm, 2 m, 4.11 cm; the paring knife: 4 m, 1.62 cm, 2 m, 1.55 cm; and the scissors: 4 m, 2.08 cm, 2 m, 0.95 cm. Handle-throw penetration-depths were: 4 m: 3.77 cm and 2 m: 2.86 cm; blade-throw depths were: 4 m: 3.14 cm and 2 m: 2.69 cm. Overarm-throw penetration-depths were: 4 m: 3.62 cm and 2 m: 3.25 cm; and underarm-throw penetration-depths were 4 m: 3.30 cm and 2 m: 2.30 cm. No thrust-throws with the paring knife and scissors could pierce the target. The tips pointed toward the target at angles of 60°-120°, earlier in handle-throws than blade-throws, especially with the paring knife and the scissors. When thrown, especially with a handle-held technique, heavier objects pierced more often and more deeply. Thrust-throws at short distances are unlikely to pierce a human.


Asunto(s)
Artículos Domésticos , Modelos Biológicos , Heridas Punzantes/patología , Adulto , Femenino , Medicina Legal , Gelatina , Humanos , Masculino
9.
Int J Legal Med ; 131(5): 1363-1368, 2017 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-28303395

RESUMEN

PURPOSE: The fact that ferromagnetic bullets can move in air or gelatine when subjected to magnetic resonance (MR) units is well known. A previous study showed that the movement of 7.5-mm GP 11 Suisse bullets also depends on their orientation toward the gantry. In order to compare the movement in gelatine to that in real tissue, we decided to measure the movement of these bullets, as well as 9-mm Luger bullets, in the brain and liver. METHODS: The GP 11 and 9-mm Luger bullets were inserted into the fresh calf brain or pig liver either vertically or horizontally in the x- or z-axis to the gantry. Before and after exposure to a 3-T MR unit, their position was documented by CT. RESULTS: GP 11 bullets rotated more readily and in general proved to be more mobile than the 9-mm Luger. All GP 11 bullets and a large amount of the 9-mm Luger bullets exited the brain. Sliding toward the gantry was easier for 9-mm Luger bullets in the brain than in the liver. CONCLUSIONS: The orientation of a ferromagnetic object influences its mobility in a strong magnetic field. Tipping is easier than sliding for longish ferromagnetic projectiles, probably due to the lesser tissue resistance. The bullets moved more readily in biological tissue, especially brain tissue, compared to gelatine, thus implying that gelatine is not a suitable substitute for soft tissues when examining the movement of ferromagnetic objects in MR units.


Asunto(s)
Encéfalo/diagnóstico por imagen , Cuerpos Extraños/diagnóstico por imagen , Balística Forense , Hígado/diagnóstico por imagen , Imagen por Resonancia Magnética , Heridas por Arma de Fuego/diagnóstico por imagen , Animales , Bovinos , Armas de Fuego , Gelatina , Porcinos
10.
Am J Forensic Med Pathol ; 38(1): 74-77, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28045743

RESUMEN

Pulmonary fat embolism (PFE) is frequent in blunt trauma and may occasionally lead to death. A correlation between fracture grade and severity and PFE grade has been described before, but no correlation between PFE and survival time, fat crushing extent, fat crush grade, or number of body regions with fractures could be noted in this small study. To further examine this, we decided to examine the aforementioned points in a far larger study group.Autopsy protocols of 188 nonresuscitated fatalities with blunt trauma and without right heart injury, which underwent whole body dissection, were retrospectively reviewed concerning the presence and the severity of PFE, injuries, survival time, age, sex, and the body mass index.The fracture grade, the fracture severity, and the number of the fractured regions correlated very well with the grade of PFE, but the crushed regions, crush grade, and crush severity did not. We observed a time correlation between survival time and PFE only in the sense that very rapid deaths were often PFE negative. High-grade PFE was observed most often in patients having died less than 6 hours after the incident, and PFE grades of 2 or more were occasionally noted even after 48 hours.


Asunto(s)
Embolia Grasa/patología , Puntaje de Gravedad del Traumatismo , Embolia Pulmonar/patología , Heridas no Penetrantes/patología , Embolia Grasa/clasificación , Femenino , Patologia Forense , Fracturas Óseas/patología , Humanos , Masculino , Persona de Mediana Edad , Embolia Pulmonar/clasificación , Estudios Retrospectivos , Factores de Tiempo
11.
Forensic Sci Med Pathol ; 13(4): 464-467, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-29063459

RESUMEN

Pneumopericardium (PPC) and Tension Pneumopericardium (TPPC) refer to collections of gas in the pericardial cavity, the latter resulting in air tamponade and cardiac compromise. Following penetrating chest injuries, PPC and TPPC appear to be uncommon findings associated with a high mortality and correlated with other thoracic trauma. Diagnosis of PPC and TPPC is difficult relying on conventional autopsy alone, while postmortem computed tomography (PMCT) shows a high sensitivity for the detection of internal gas collections. Possibly due to difficulty in detection, PPC and TPPC have not been discussed from a forensic point of view and many lethal cases of PPC and TPPC might have been missed in medicolegal investigations. In this report, we present a case with suicidal, penetrating stab wounds to the chest resulting in a TPPC with lethal air tamponade documented by PMCT.


Asunto(s)
Neumopericardio/etiología , Neumotórax/etiología , Suicidio , Traumatismos Torácicos/complicaciones , Heridas Punzantes/complicaciones , Adulto , Taponamiento Cardíaco/etiología , Humanos , Masculino , Neumopericardio/diagnóstico por imagen , Neumotórax/diagnóstico por imagen , Tomografía Computarizada por Rayos X
12.
Forensic Sci Med Pathol ; 13(3): 367-371, 2017 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-28589523

RESUMEN

A case is presented in which pre-autopsy postmortem computed tomography (PMCT) revealed an unexpected brain abscess with a related frontal sinusitis and an erosion of the posterior wall of the frontal sinus. PMCT findings enabled the forensic pathologists to adapt protective measures during autopsy and protect their health from infection. Pre-autopsy PMCT has been also useful in the early differential diagnosis procedure. The complementary use of postmortem imaging and autopsy can improve the quality of forensic death investigations.


Asunto(s)
Autopsia/métodos , Absceso Encefálico/diagnóstico por imagen , Sinusitis Frontal/diagnóstico por imagen , Tomografía Computarizada Multidetector , Absceso Encefálico/microbiología , Edema Encefálico/diagnóstico por imagen , Edema Encefálico/microbiología , Patologia Forense , Sinusitis Frontal/microbiología , Humanos , Masculino , Persona de Mediana Edad , Infecciones Estreptocócicas/diagnóstico , Imagen de Cuerpo Entero
13.
Forensic Sci Med Pathol ; 12(4): 394-398, 2016 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-27503509

RESUMEN

PURPOSE: In addition to reconstructing the course of events, the medical examiner will often have to answer questions regarding the force necessary to inflict a certain injury in stabbing incidents. Several groups have examined the force needed to penetrate soft-tissue and clothing; however, no studies addressing the energy needed for penetrating ribs exist. Therefore, we decided to investigate this force on an animal model. METHOD: Ribs from healthy, 8 to 10-month-old pigs were used as a substitute for human ribs. These ribs were then stabbed either transversely or longitudinally with two different pocket-knife blades, namely a Swiss Army pocket knife and a sturdier pocket knife (Classic Schnitzmesser, Herbertz Solingen) dropped from a drop-tower at defined heights and therefore defined energies. RESULTS: Longitudinally orientated stabs showed complete piercing of the ribs at approximately 11 Joules (J) or with a stabbing force in excess of 906 Newton (N) for both blade types. Transversely orientated stabs, however, displayed complete piercing between 11 and 16 J, or in excess of 1198 N, with the sturdy pocket knife tending to require a little more energy than the Swiss army pocket knife. CONCLUSIONS: Young adult porcine ribs are completely pierced by pocket knife blades at energies between 11 and 16 J. Assuming the porcine ribs are comparable to those ribs of young adult humans, our results indicate that a complete penetration of the chest wall through the ribs by stabbing with a pocket knife is rather easily achieved.


Asunto(s)
Costillas/lesiones , Costillas/patología , Heridas Punzantes/patología , Animales , Fenómenos Biomecánicos , Patologia Forense , Modelos Animales , Porcinos , Armas , Heridas Punzantes/fisiopatología
14.
Eur Radiol ; 25(9): 2745-53, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25708963

RESUMEN

OBJECTIVES: To investigate the magnetic properties of different types of projectiles and qualify the metal artefact reduction technique for diagnostic and/or forensic MRI. MATERIALS AND METHODS: Ten different projectiles embedded in ordnance gelatine blocks underwent an in vitro 1.5-T MR study with seven sequences including a recently developed metal artefact reduction sequence (Advanced WARP) combining VAT (view-angle-tilting) and SEMAC (slice-encoding metal-artefact-correction). Resulting image quality (five-point scale: 1=best; 5=worst) was scored. Quantifiable magnetic characteristics were correlated with qualitative rating of the MR sequences and torque dislodgment. RESULTS: Metal artefact reduction sequence (median: 2.5) significantly (p < 0.001) improves depiction of projectiles in comparison to all other MR pulse sequences (median: 4.75). Images from diamagnetic composed bullets (median: 2) are much less disturbed compared to magnetic attracted ones (median: 5). Correlation (0.623) between deflection angle measurement (ferromagnetic mean 84.2°; paramagnetic 62°; diamagnetic mean 0°) and median qualitative image quality was highly significant (p = 0.027). Torque dislodgement was distinct for elongated magnetic attracted projectiles. CONCLUSIONS: Significant improvement of MR imaging of projectiles using metal artefact reduction techniques has important implications for diagnostic/forensic work-up. The correlations between magnetic attraction force, deflection-angle results and image properties demonstrate that the MR safety of projectiles can be estimated with one of these methods. KEY POINTS: • Metal artefact reduction sequence improves overall image quality of bullets (p < 0.001). • Deflection angle assessment significantly predicts image quality of bullets (p = 0.027). • Classification of projectiles' magnetic properties based on artefacts' characteristics is possible. • Classifying of bullets has important implications in diagnostic and forensic imaging. • Identification of projectiles' magnetic attributes improves estimation of patients' injury risk.


Asunto(s)
Artefactos , Armas de Fuego , Interpretación de Imagen Asistida por Computador/métodos , Imagen por Resonancia Magnética/métodos , Metales , Fantasmas de Imagen , Adulto , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos
15.
Forensic Sci Med Pathol ; 11(4): 544-51, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26514689

RESUMEN

PURPOSE: Ferromagnetic bullets can move in air or gelatin in magnetic resonance (MR) units. According to our experience, ferromagnetic bullets do not always present consistent movement. We examined factors affecting ferromagnetic projectile movement in a 1.5T and a 3T MR unit, focusing in this study on the steel-jacketed Swiss ordnance ammunition 7.5 mm GP11 Suisse. METHODS: Five 7.5 mm GP11 Suisse bullets were embedded horizontally and vertically in 10 % ordnance gelatin phantoms. Before and after exposing the bullets to 1.5T (Siemens) and 3T (Philips) MR units each bullet's position was documented by a CT scan. In a second phase, the magnetic polarization of the bullets in relation to the MR units was measured by a dry magnetic portable compass (Suunto). RESULTS: Our results showed that the displacement of the bullets increased when subjected to a stronger magnetic field (max. Movement 1.5T: 24.4 mm vs. 3T: 101.5 mm) and that the position, i.e. orientation of the bullet toward the gantry, strongly influenced its mobility (horizontally embedded projectiles showed poor movement, vertically placed ones strong movement). One of the bullets presented a 180° rotation in the 3T MR unit. Magnetization and changing of the polarization of these ferromagnetic bullets is possible when subjected to MR units. CONCLUSION: In conclusion, the location of a bullet, and its orientation toward the gantry must be taken into account when assessing the risk of performing an MR examination on a gunshot victim in clinical and in forensic cases.


Asunto(s)
Armas de Fuego , Gelatina , Campos Magnéticos , Imagen por Resonancia Magnética/métodos , Balística Forense , Humanos , Modelos Biológicos , Tomografía Computarizada Multidetector
16.
Radiographics ; 34(3): 830-46, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24819799

RESUMEN

Whole-body postmortem computed tomographic (CT) angiography is a promising new development in forensic radiology that has the potential to improve vascular and soft-tissue imaging beyond levels currently achievable with unenhanced postmortem CT. Postmortem access to the vascular system and injection of contrast medium are different from those steps in clinical (antemortem) radiology. Because there is no circulation in a corpse that could transport or dilute a contrast medium, the injection must be performed by using a roller pump to fill the vasculature (arterial and venous) with a mixture of a water-soluble iodized contrast medium and polyethylene glycol. In contrast to a classic autopsy, postmortem CT angiography is a minimally invasive procedure. It allows the diagnosis of vascular lesions without the disruption or destruction of anatomic structures, which could result in a loss of evidence in a criminal investigation. Furthermore, postmortem CT angiography facilitates the display of vascular pathologic conditions in areas that are not typically covered with autopsy alone, such as the craniocervical junction and the small pelvis. Therefore, postmortem CT angiography adds substantial value to the classic forensic autopsy; cross-sectional data can be reevaluated objectively at any time and are fully reproducible as counterexpertise, which is as useful in the fields of forensic medicine and pathology as in clinical research. Familiarity with the capabilities of postmortem CT angiography may help radiologists working with forensic cases improve their diagnostic performance.


Asunto(s)
Angiografía/métodos , Causas de Muerte , Diagnóstico , Medicina Legal/métodos , Tomografía Computarizada por Rayos X/métodos , Heridas y Lesiones/diagnóstico por imagen , Autopsia , Coagulación Sanguínea , Medios de Contraste , Fracturas Óseas/diagnóstico por imagen , Máquina Corazón-Pulmón , Humanos , Bombas de Infusión , Cambios Post Mortem , Traumatismos de los Tejidos Blandos/diagnóstico por imagen , Lesiones del Sistema Vascular/diagnóstico por imagen
17.
BMC Pediatr ; 14: 15, 2014 Jan 20.
Artículo en Inglés | MEDLINE | ID: mdl-24438163

RESUMEN

BACKGROUND: In light of declining autopsy rates around the world, post-mortem MR imaging is a promising alternative to conventional autopsy in the investigation of infant death. A major drawback of this non-invasive autopsy approach is the fact that histopathological and microbiological examination of the tissue is not possible. The objective of this prospective study is to compare the performance of minimally invasive, virtual autopsy, including CT-guided biopsy, with conventional autopsy procedures in a paediatric population. METHODS/DESIGN: Foetuses, newborns and infants that are referred for autopsy at three different institutions associated with the University of Zurich will be eligible for recruitment. All bodies will be examined with a commercial CT and a 3 Tesla MRI scanner, masked to the results of conventional autopsy. After cross-sectional imaging, CT-guided tissue sampling will be performed by a multifunctional robotic system (Virtobot) allowing for automated post-mortem biopsies. Virtual autopsy results will be classified with regards to the likely final diagnosis and major pathological findings and compared to the results of conventional autopsy, which remains the diagnostic gold standard. DISCUSSION: There is an urgent need for the development of alternative post-mortem examination methods, not only as a counselling tool for families and as a quality control measure for clinical diagnosis and treatment but also as an instrument to advance medical knowledge and clinical practice. This interdisciplinary study will determine whether virtual autopsy will narrow the gap in information between non-invasive and traditional autopsy procedures. TRIAL REGISTRATION: ClinicalTrials.gov: NCT01888380.


Asunto(s)
Autopsia/métodos , Biopsia Guiada por Imagen , Estudios Transversales , Feto/patología , Humanos , Lactante , Recién Nacido , Estudios Prospectivos , Método Simple Ciego
18.
Forensic Sci Med Pathol ; 9(2): 163-9, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-23264199

RESUMEN

The goal of this study was to investigate the use of dual-energy computed tomography (CT) in differentiating frequently encountered foreign material on CT images using a standard single-source CT scanner. We scanned 20 different, forensically relevant materials at two X-Ray energy levels (80 and 130 kVp) on CT. CT values were measured in each object at both energy levels. Intraclass correlation coefficient (ICC) was used to determine intra-reader reliability. Analysis of variance (ANOVA) was performed to assess significance levels between X-Ray attenuation at 80 and 130 kVp. T test was used to investigate significance levels between mean HU values of individual object pairings at single energy levels of 80 and 130 kVp, respectively. ANOVA revealed that the difference in attenuation between beam energies of 80 kVp compared to 130 kVp was statistically significant (p < 0.005) for all materials except brass and lead. ICC was excellent at 80 kVp (0.999, p < 0.001) and at 130 kVp (0.998, p < 0.001). T test showed that using single energy levels of 80 and 130 kVp respectively 181/190 objects pairs could be differentiated from one another based on HU measurements. Using the combined information from both energy levels, 189/190 object pairs could be differentiated. Scanning with different energy levels is a simple way to apply dual-energy technique on a regular single-energy CT and improves the ability to differentiate foreign bodies with CT, based on their attenuation values.


Asunto(s)
Cuerpos Extraños/diagnóstico por imagen , Medicina Legal/métodos , Tomografía Computarizada por Rayos X , Medicina Legal/instrumentación , Variaciones Dependientes del Observador , Fantasmas de Imagen , Reproducibilidad de los Resultados , Tomografía Computarizada por Rayos X/instrumentación
19.
AJR Am J Roentgenol ; 199(6): 1186-92, 2012 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23169707

RESUMEN

OBJECTIVE: The aim of this study was to determine the sensitivity and specificity of postmortem whole-body MRI for typical injuries resulting from traumatic causes of death. MATERIALS AND METHODS: Forty cases of accidental death were evaluated with postmortem whole-body MRI. Imaging was conducted according to a standard protocol, and each examination had an average duration of 90 minutes. The imaging findings were correlated with the autopsy findings, which served as the reference standard. RESULTS: MRI showed the main pathologic process leading to death in 39 of the 40 cases. The sensitivity of postmortem MRI ranged from 100% (pneumothorax) to 40% (fractures of the upper extremities). In general, MRI had a high level of performance for depicting soft-tissue lesions, such as subcutaneous hematoma (e.g., galeal hematoma with a sensitivity 95%). The sensitivity of MRI was remarkably lower for lesions of the upper abdominal organs (liver, 80%; spleen, 50%; pancreas, 60%; kidneys, 66%). CONCLUSION: Postmortem whole-body MRI had overall good performance for depicting traumatic findings in corpses and therefore may serve an important role as an adjunct to classic autopsy for the forensic examination of cases of traumatic cause of death. However, the reduced sensitivity of postmortem MRI for lacerations of the upper abdominal organs and the observed superimposition of antemortem findings and postmortem findings (e.g., in the pulmonary tissue) in this retrospective study suggest that whole-body postmortem MRI not be recommended as a replacement for classic autopsy.


Asunto(s)
Medicina Legal , Imagen por Resonancia Magnética/métodos , Imagen de Cuerpo Entero , Heridas y Lesiones/mortalidad , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Autopsia , Causas de Muerte , Niño , Preescolar , Femenino , Humanos , Interpretación de Imagen Asistida por Computador , Lactante , Masculino , Persona de Mediana Edad , Cambios Post Mortem , Sensibilidad y Especificidad
20.
Radiographics ; 32(5): 1553-9, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22977034

RESUMEN

The study of fossils permits the reconstruction of past life on our planet and enhances our understanding of evolutionary processes. However, many fossils are difficult to recognize, being encased in a lithified matrix whose tedious removal is required before examination is possible. The authors describe the use of multidetector computed tomography (CT) in locating, identifying, and examining fossil remains of crocodilians (Mesosuchia) embedded in hard shale, all without removing the matrix. In addition, they describe how three-dimensional (3D) reformatted CT images provided details that were helpful for extraction and preparation. Multidetector CT can help experienced paleontologists localize and characterize fossils in the matrix of a promising rock specimen in a nondestructive manner. Moreover, with its capacity to generate highly accurate 3D images, multidetector CT can help determine whether the fossils warrant extraction and can assist in planning the extraction process. Thus, multidetector CT may well become an invaluable tool in the field of paleoradiology.


Asunto(s)
Caimanes y Cocodrilos , Huesos/diagnóstico por imagen , Fósiles , Tomografía Computarizada por Rayos X/métodos , Animales , Proyectos Piloto
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