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1.

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

Walker, Amy K; Yang, Fajun; Jiang, Karen; Ji, Jun-Yuan; Watts, Jennifer L; Purushotham, Aparna; Boss, Olivier; Hirsch, Michael L; Ribich, Scott; Smith, Jesse J; Israelian, Kristine; Westphal, Christoph H; Rodgers, Joseph T; Shioda, Toshi; Elson, Sarah L; Mulligan, Peter; Najafi-Shoushtari, Hani; Black, Josh C; Thakur, Jitendra K; Kadyk, Lisa C; Whetstine, Johnathan R; Mostoslavsky, Raul; Puigserver, Pere; Li, Xiaoling; Dyson, Nicholas J; Hart, Anne C; Näär, Anders M.

Genes Dev; 24(13): 1403-17, 2010 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-20595232

2.

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Milne, Jill C; Lambert, Philip D; Schenk, Simon; Carney, David P; Smith, Jesse J; Gagne, David J; Jin, Lei; Boss, Olivier; Perni, Robert B; Vu, Chi B; Bemis, Jean E; Xie, Roger; Disch, Jeremy S; Ng, Pui Yee; Nunes, Joseph J; Lynch, Amy V; Yang, Hongying; Galonek, Heidi; Israelian, Kristine; Choy, Wendy; Iffland, Andre; Lavu, Siva; Medvedik, Oliver; Sinclair, David A; Olefsky, Jerrold M; Jirousek, Michael R; Elliott, Peter J; Westphal, Christoph H.

Nature; 450(7170): 712-6, 2007 Nov 29.

Artículo en Inglés | MEDLINE | ID: mdl-18046409

3.

Resveratrol improves health and survival of mice on a high-calorie diet.

Baur, Joseph A; Pearson, Kevin J; Price, Nathan L; Jamieson, Hamish A; Lerin, Carles; Kalra, Avash; Prabhu, Vinayakumar V; Allard, Joanne S; Lopez-Lluch, Guillermo; Lewis, Kaitlyn; Pistell, Paul J; Poosala, Suresh; Becker, Kevin G; Boss, Olivier; Gwinn, Dana; Wang, Mingyi; Ramaswamy, Sharan; Fishbein, Kenneth W; Spencer, Richard G; Lakatta, Edward G; Le Couteur, David; Shaw, Reuben J; Navas, Placido; Puigserver, Pere; Ingram, Donald K; de Cabo, Rafael; Sinclair, David A.

Nature; 444(7117): 337-42, 2006 Nov 16.

Artículo en Inglés | MEDLINE | ID: mdl-17086191

4.

Serotonin reciprocally regulates melanocortin neurons to modulate food intake.

Heisler, Lora K; Jobst, Erin E; Sutton, Gregory M; Zhou, Ligang; Borok, Erzsebet; Thornton-Jones, Zoe; Liu, Hong Yan; Zigman, Jeffrey M; Balthasar, Nina; Kishi, Toshiro; Lee, Charlotte E; Aschkenasi, Carl J; Zhang, Chen-Yu; Yu, Jia; Boss, Olivier; Mountjoy, Kathleen G; Clifton, Peter G; Lowell, Bradford B; Friedman, Jeffrey M; Horvath, Tamas; Butler, Andrew A; Elmquist, Joel K; Cowley, Michael A.

Neuron; 51(2): 239-49, 2006 Jul 20.

Artículo en Inglés | MEDLINE | ID: mdl-16846858

5.

GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

Kotani, Ko; Peroni, Odile D; Minokoshi, Yasuhiko; Boss, Olivier; Kahn, Barbara B.

J Clin Invest; 114(11): 1666-75, 2004 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-15578099

6.

A role for skeletal muscle stearoyl-CoA desaturase 1 in control of thermogenesis.

Mainieri, Davide; Summermatter, Serge; Seydoux, Josiane; Montani, Jean-Pierre; Rusconi, Sandro; Russell, Aaron P; Boss, Olivier; Buchala, Antony J; Dulloo, Abdul G.

FASEB J; 20(10): 1751-3, 2006 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16809433

7.

Leptin directly stimulates thermogenesis in skeletal muscle.

Dulloo, Abdul G; Stock, Michael J; Solinas, Giovanni; Boss, Olivier; Montani, Jean Pierre; Seydoux, Josiane.

FEBS Lett; 515(1-3): 109-13, 2002 Mar 27.

Artículo en Inglés | MEDLINE | ID: mdl-11943204

8.

Recruitment of brown adipose tissue as a therapy for obesity-associated diseases.

Boss, Olivier; Farmer, Stephen R.

Front Endocrinol (Lausanne); 3: 14, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22654854

9.

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.

Smith, Jesse J; Kenney, Renée Deehan; Gagne, David J; Frushour, Brian P; Ladd, William; Galonek, Heidi L; Israelian, Kristine; Song, Jeffrey; Razvadauskaite, Giedre; Lynch, Amy V; Carney, David P; Johnson, Robin J; Lavu, Siva; Iffland, Andre; Elliott, Peter J; Lambert, Philip D; Elliston, Keith O; Jirousek, Michael R; Milne, Jill C; Boss, Olivier.

BMC Syst Biol; 3: 31, 2009 Mar 10.

Artículo en Inglés | MEDLINE | ID: mdl-19284563

10.

Sirtuins--novel therapeutic targets to treat age-associated diseases.

Lavu, Siva; Boss, Olivier; Elliott, Peter J; Lambert, Philip D.

Nat Rev Drug Discov; 7(10): 841-53, 2008 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-18827827

11.

Targeting PGC-1 alpha to control energy homeostasis.

Wu, Zhidan; Boss, Olivier.

Expert Opin Ther Targets; 11(10): 1329-38, 2007 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-17907962

12.

The obesity epidemic: current and future pharmacological treatments.

Hofbauer, Karl G; Nicholson, Janet R; Boss, Olivier.

Annu Rev Pharmacol Toxicol; 47: 565-92, 2007.

Artículo en Inglés | MEDLINE | ID: mdl-17002599

13.

Adipose targets for obesity drug development.

Boss, Olivier; Bergenhem, Nils.

Expert Opin Ther Targets; 10(1): 119-34, 2006 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-16441232

14.

Divergence of melanocortin pathways in the control of food intake and energy expenditure.

Balthasar, Nina; Dalgaard, Louise T; Lee, Charlotte E; Yu, Jia; Funahashi, Hisayuki; Williams, Todd; Ferreira, Manuel; Tang, Vinsee; McGovern, Robert A; Kenny, Christopher D; Christiansen, Lauryn M; Edelstein, Elizabeth; Choi, Brian; Boss, Olivier; Aschkenasi, Carl; Zhang, Chen-yu; Mountjoy, Kathleen; Kishi, Toshiro; Elmquist, Joel K; Lowell, Bradford B.

Cell; 123(3): 493-505, 2005 Nov 04.

Artículo en Inglés | MEDLINE | ID: mdl-16269339

15.

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.

Lin, Jiandie; Wu, Hai; Tarr, Paul T; Zhang, Chen-Yu; Wu, Zhidan; Boss, Olivier; Michael, Laura F; Puigserver, Pere; Isotani, Eiji; Olson, Eric N; Lowell, Bradford B; Bassel-Duby, Rhonda; Spiegelman, Bruce M.

Nature; 418(6899): 797-801, 2002 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-12181572

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