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1.
A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization.
Cancer Cell;
42(2): 301-316.e9, 2024 02 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38215750
2.
AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer.
Nat Commun;
13(1): 4116, 2022 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35840573
3.
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models.
Mol Cancer Ther;
20(2): 250-262, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33310762
4.
Translational strategy using multiple nuclear imaging biomarkers to evaluate target engagement and early therapeutic efficacy of SAR439859, a novel selective estrogen receptor degrader.
EJNMMI Res;
10(1): 70, 2020 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-32601772
5.
Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer.
J Med Chem;
63(2): 512-528, 2020 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31721572
6.
Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.
Cell Chem Biol;
25(6): 705-717.e11, 2018 06 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29628435
7.
Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation.
Eur J Pharmacol;
517(3): 174-81, 2005 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-15987634
8.
SAR103168: a tyrosine kinase inhibitor with therapeutic potential in myeloid leukemias.
Leuk Lymphoma;
54(7): 1488-99, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23121564
9.
Subversion and utilization of the host cell cyclic adenosine 5'-monophosphate/protein kinase A pathway by Brucella during macrophage infection.
J Immunol;
170(11): 5607-14, 2003 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12759440
10.
Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716.
J Biol Chem;
278(26): 23731-7, 2003 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-12690115
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