Psychometric Properties and Factor Structure of the Short Form of the Affective Lability Scale in Adult Patients With ADHD.

Objective: Affective lability is an important dimension of adult ADHD, associated with marked impairments and worse outcomes. A valid and quick tool to measure affective lability may therefore be of interest. Method: In 187 adult ADHD patients, we explored psychometric properties of the Affective Lability Scale-Short Form (ALS-18 items). We analyzed the construct validity and the external validity of the scale. Patients were compared with 48 healthy adult controls. Results: The three-factor structure of the ALS-18 presented a good fit and a good internal consistency. The correlations between the ALS-18 and ADHD symptoms and other psychological dimensions were, respectively, low and moderate. ALS-18 scores were higher in patients than in healthy adults. Conclusion: ALS-18 showed good psychometric properties in ADHD adult patients, allowing us to recommend the implementation of ALS-18 in assessing affective lability for clinical and research purposes. Use of ALS-18 should improve the clinical assessment of affective lability in adult ADHD patients.

The development of the SGI-16: a shortened sensory gating deficit and distractibility questionnaire for adults with ADHD.

The Sensory Gating Inventory (SGI) is a questionnaire composed of 36 items designed to investigate abnormal perception related to the inability to control sensitivity to sensory stimuli frequently reported in adult with ADHD. This questionnaire can be considered too lengthy to be taken by people with ADHD, and a shortened version is needed. One hundred and sixty-three adults with ADHD responded to the SGI-36. An item reduction process took into account both the results of statistical analyses and the expertise of a steering committee. Construct validity, reliability, and external validity were tested for a short version (16 items). The structure of the SGI-16 was confirmed by principal components factor analysis. Cronbach's alpha coefficients ranged from 0.78 to 0.89. The SGI-16 dimension scores were highly correlated with their respective SGI-36 dimension scores. The SGI-16 seems to be both appropriate and useful for use in clinical practice to investigate perceptual abnormalities in adults with ADHD.

Sensory gating in adult with attention-deficit/hyperactivity disorder: Event-evoked potential and perceptual experience reports comparisons with schizophrenia.

BACKGROUND: In daily life, adults with attention-deficit/hyperactivity disorder (ADHD) report abnormal perceptual experiences that can be related to sensory gating deficit. This study investigated and compared P50 suppression (a neurophysiological measure of sensory gating) and perceptual abnormalities related to sensory gating deficit in ADHD and schizophrenias patients. METHODS: Three groups were compared: 24 adults with ADHD, 24 patients with schizophrenia and 24 healthy subjects. The Sensory Gating Inventory (SGI), a validated self-report questionnaire, was used to measure perceptual abnormalities related to sensory gating deficit. P50 suppression was measured by P50 amplitude changes in a dual-click conditioning-testing auditory event-related potential procedure. RESULTS: Adults with ADHD had significantly higher scores on the SGI and significantly lower P50 suppression than healthy subjects. These deficits were similar to those found in patients with schizophrenia. A correlation was found between both the SGI and P50 suppression data in adults with ADHD and patients with schizophrenia. DISCUSSION: The findings confirm previous results found in patients with schizophrenia. Moreover, adults with ADHD, similar to patients with schizophrenia, had abnormal P50 suppression and reported being flooded with sensory stimuli. Abnormal neurophysiologic responses to repetitive stimuli gave rise to clinically abnormal perceptions.