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1.

A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis.

Wang, Yuqing; Zhu, Duolong; Ortiz-Velez, Laura C; Perry, Jacob L; Pennington, Michael W; Hyser, Joseph M; Britton, Robert A; Beeton, Christine.

Proc Natl Acad Sci U S A; 120(2): e2211977120, 2023 01 10.

Artículo en Inglés | MEDLINE | ID: mdl-36595694

2.

Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power.

Norsigian, Charles J; Danhof, Heather A; Brand, Colleen K; Midani, Firas S; Broddrick, Jared T; Savidge, Tor C; Britton, Robert A; Palsson, Bernhard O; Spinler, Jennifer K; Monk, Jonathan M.

Proc Natl Acad Sci U S A; 119(18): e2119396119, 2022 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-35476524

3.

RbgA ensures the correct timing in the maturation of the 50S subunits functional sites.

Seffouh, Amal; Trahan, Chirstian; Wasi, Tanzila; Jain, Nikhil; Basu, Kaustuv; Britton, Robert A; Oeffinger, Marlene; Ortega, Joaquin.

Nucleic Acids Res; 50(19): 10801-10816, 2022 10 28.

Artículo en Inglés | MEDLINE | ID: mdl-35141754

4.

Probiotics and the Microbiome-How Can We Help Patients Make Sense of Probiotics?

Britton, Robert A; Hoffmann, Diane E; Khoruts, Alexander.

Gastroenterology; 160(2): 614-623, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33307023

5.

Fusobacteriumnucleatum Adheres to Clostridioides difficile via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mucus.

Engevik, Melinda A; Danhof, Heather A; Auchtung, Jennifer; Endres, Bradley T; Ruan, Wenly; Bassères, Eugénie; Engevik, Amy C; Wu, Qinglong; Nicholson, Maribeth; Luna, Ruth Ann; Garey, Kevin W; Crawford, Sue E; Estes, Mary K; Lux, Renate; Yacyshyn, Mary Beth; Yacyshyn, Bruce; Savidge, Tor; Britton, Robert A; Versalovic, James.

Gastroenterology; 160(4): 1301-1314.e8, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33227279

6.

Drivers of transcriptional variance in human intestinal epithelial organoids.

Criss, Zachary K; Bhasin, Nobel; Di Rienzi, Sara C; Rajan, Anubama; Deans-Fielder, Kali; Swaminathan, Ganesh; Kamyabi, Nabiollah; Zeng, Xi-Lei; Doddapaneni, Harsha; Menon, Vipin K; Chakravarti, Deepavali; Estrella, Clarissa; Yu, Xiaomin; Patil, Ketki; Petrosino, Joseph F; Fleet, James C; Verzi, Michael P; Christakos, Sylvia; Helmrath, Michael A; Arimura, Sumimasa; DePinho, Ronald A; Britton, Robert A; Maresso, Anthony W; Grande-Allen, K Jane; Blutt, Sarah E; Crawford, Sue E; Estes, Mary K; Ramani, Sasirekha; Shroyer, Noah F.

Physiol Genomics; 53(11): 486-508, 2021 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-34612061

7.

The metabolic profile of Bifidobacterium dentium reflects its status as a human gut commensal.

Engevik, Melinda A; Danhof, Heather A; Hall, Anne; Engevik, Kristen A; Horvath, Thomas D; Haidacher, Sigmund J; Hoch, Kathleen M; Endres, Bradley T; Bajaj, Meghna; Garey, Kevin W; Britton, Robert A; Spinler, Jennifer K; Haag, Anthony M; Versalovic, James.

BMC Microbiol; 21(1): 154, 2021 05 24.

Artículo en Inglés | MEDLINE | ID: mdl-34030655

8.

Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.

Seffouh, Amal; Jain, Nikhil; Jahagirdar, Dushyant; Basu, Kaustuv; Razi, Aida; Ni, Xiaodan; Guarné, Alba; Britton, Robert A; Ortega, Joaquin.

Nucleic Acids Res; 47(19): 10414-10425, 2019 11 04.

Artículo en Inglés | MEDLINE | ID: mdl-31665744

9.

Role of Era in assembly and homeostasis of the ribosomal small subunit.

Razi, Aida; Davis, Joseph H; Hao, Yumeng; Jahagirdar, Dushyant; Thurlow, Brett; Basu, Kaustuv; Jain, Nikhil; Gomez-Blanco, Josue; Britton, Robert A; Vargas, Javier; Guarné, Alba; Woodson, Sarah A; Williamson, James R; Ortega, Joaquin.

Nucleic Acids Res; 47(15): 8301-8317, 2019 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-31265110

10.

Enhancing responsiveness of human jejunal enteroids to host and microbial stimuli.

Ruan, Wenly; Engevik, Melinda A; Chang-Graham, Alexandra L; Danhof, Heather A; Goodwin, Annie; Engevik, Kristen A; Shi, Zhongcheng; Hall, Anne; Rienzi, Sara C Di; Venable, Susan; Britton, Robert A; Hyser, Joseph; Versalovic, James.

J Physiol; 598(15): 3085-3105, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32428244

11.

Human intestinal enteroids as a model of Clostridioides difficile-induced enteritis.

Engevik, Melinda A; Danhof, Heather A; Chang-Graham, Alexandra L; Spinler, Jennifer K; Engevik, Kristen A; Herrmann, Beatrice; Endres, Bradley T; Garey, Kevin W; Hyser, Joseph M; Britton, Robert A; Versalovic, James.

Am J Physiol Gastrointest Liver Physiol; 318(5): G870-G888, 2020 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-32223302

12.

The impact of recent improvements in cryo-electron microscopy technology on the understanding of bacterial ribosome assembly.

Razi, Aida; Britton, Robert A; Ortega, Joaquin.

Nucleic Acids Res; 45(3): 1027-1040, 2017 02 17.

Artículo en Inglés | MEDLINE | ID: mdl-28180306

13.

Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation.

Daeffler, Kristina N-M; Galley, Jeffrey D; Sheth, Ravi U; Ortiz-Velez, Laura C; Bibb, Christopher O; Shroyer, Noah F; Britton, Robert A; Tabor, Jeffrey J.

Mol Syst Biol; 13(4): 923, 2017 04 03.

Artículo en Inglés | MEDLINE | ID: mdl-28373240

14.

Protective role of commensal bacteria in Sjögren Syndrome.

Zaheer, Mahira; Wang, Changjun; Bian, Fang; Yu, Zhiyuan; Hernandez, Humberto; de Souza, Rodrigo G; Simmons, Ken T; Schady, Deborah; Swennes, Alton G; Pflugfelder, Stephen C; Britton, Robert A; de Paiva, Cintia S.

J Autoimmun; 93: 45-56, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-29934134

15.

Genome alterations associated with improved transformation efficiency in Lactobacillus reuteri.

Ortiz-Velez, Laura; Ortiz-Villalobos, Javiera; Schulman, Abby; Oh, Jee-Hwan; van Pijkeren, Jan-Peter; Britton, Robert A.

Microb Cell Fact; 17(1): 138, 2018 Sep 03.

Artículo en Inglés | MEDLINE | ID: mdl-30176942

16.

YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit.

Ni, Xiaodan; Davis, Joseph H; Jain, Nikhil; Razi, Aida; Benlekbir, Samir; McArthur, Andrew G; Rubinstein, John L; Britton, Robert A; Williamson, James R; Ortega, Joaquin.

Nucleic Acids Res; 44(17): 8442-55, 2016 09 30.

Artículo en Inglés | MEDLINE | ID: mdl-27484475

17.

Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice.

Wang, Changjun; Zaheer, Mahira; Bian, Fang; Quach, Darin; Swennes, Alton G; Britton, Robert A; Pflugfelder, Stephen C; de Paiva, Cintia S.

Int J Mol Sci; 19(2)2018 Feb 13.

Artículo en Inglés | MEDLINE | ID: mdl-29438346

18.

Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis.

Spinler, Jennifer K; Auchtung, Jennifer; Brown, Aaron; Boonma, Prapaporn; Oezguen, Numan; Ross, Caná L; Luna, Ruth Ann; Runge, Jessica; Versalovic, James; Peniche, Alex; Dann, Sara M; Britton, Robert A; Haag, Anthony; Savidge, Tor C.

Infect Immun; 85(10)2017 10.

Artículo en Inglés | MEDLINE | ID: mdl-28760934

19.

Gut Microbiota and Bone Health.

Quach, Darin; Britton, Robert A.

Adv Exp Med Biol; 1033: 47-58, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-29101651

20.

Functional interaction between ribosomal protein L6 and RbgA during ribosome assembly.

Gulati, Megha; Jain, Nikhil; Davis, Joseph H; Williamson, James R; Britton, Robert A.

PLoS Genet; 10(10): e1004694, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25330043

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