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1.

Neurotoxicity of ischemic astrocytes involves STAT3-mediated metabolic switching and depends on glycogen usage.

Borbor, Mina; Yin, Dongpei; Brockmeier, Ulf; Wang, Chen; Doeckel, Marius; Pillath-Eilers, Matthias; Kaltwasser, Britta; Hermann, Dirk M; Dzyubenko, Egor.

Glia; 71(6): 1553-1569, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36810803

2.

BAG3 Overexpression Attenuates Ischemic Stroke Injury by Activating Autophagy and Inhibiting Apoptosis.

Liu, Xia; Ye, Qinlian; Huang, Zhengzheng; Li, Xiuping; Zhang, Liping; Liu, Xuan; Wu, Yun-Cheng; Brockmeier, Ulf; Hermann, Dirk M; Wang, Ya-Chao; Ren, Lijie.

Stroke; 54(8): 2114-2125, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37377010

3.

Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing.

Bernardini, André; Wolf, Alexandra; Brockmeier, Ulf; Riffkin, Helena; Metzen, Eric; Acker-Palmer, Amparo; Fandrey, Joachim; Acker, Helmut.

Am J Physiol Cell Physiol; 318(4): C719-C731, 2020 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-31967857

4.

Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells.

Classen, Fabian; Kranz, Philip; Riffkin, Helena; Pompsch, Mosche; Wolf, Alexandra; Göpelt, Kirsten; Baumann, Melanie; Baumann, Jennifer; Brockmeier, Ulf; Metzen, Eric.

Exp Cell Res; 374(1): 29-37, 2019 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-30412717

5.

The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.

Pompsch, Mosche; Vogel, Julia; Classen, Fabian; Kranz, Philip; Iliakis, George; Riffkin, Helena; Brockmeier, Ulf; Metzen, Eric.

BMC Cancer; 18(1): 1190, 2018 Nov 29.

Artículo en Inglés | MEDLINE | ID: mdl-30497423

6.

Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation.

Maxwell, Perry; Melendez-Rodríguez, Florinda; Matchett, Kyle B; Aragones, Julian; Ben-Califa, Nathalie; Jaekel, Heidelinde; Hengst, Ludger; Lindner, Herbert; Bernardini, Andre; Brockmeier, Ulf; Fandrey, Joachim; Grunert, Fritz; Oster, Howard S; Mittelman, Moshe; El-Tanani, Mohamed; Thiersch, Markus; Schneider Gasser, Edith M; Gassmann, Max; Dangoor, David; Cuthbert, Robert J; Irvine, Alexandra; Jordan, Anne; Lappin, Terence; Thompson, John; Neumann, Drorit.

Br J Haematol; 168(3): 429-42, 2015 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-25283956

7.

Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).

Janke, Kirsten; Brockmeier, Ulf; Kuhlmann, Katja; Eisenacher, Martin; Nolde, Jan; Meyer, Helmut E; Mairbäurl, Heimo; Metzen, Eric.

J Cell Sci; 126(Pt 12): 2629-40, 2013 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-23606740

8.

Measurement of ROS Levels and Membrane Potential Dynamics in the Intact Carotid Body Ex Vivo.

Bernardini, Andre; Brockmeier, Ulf; Metzen, Eric; Berchner-Pfannschmidt, Utta; Harde, Eva; Acker-Palmer, Amparo; Papkovsky, Dmitri; Acker, Helmut; Fandrey, Joachim.

Adv Exp Med Biol; 860: 55-9, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26303467

9.

LDL attenuates VEGF-induced angiogenesis via mechanisms involving VEGFR2 internalization and degradation following endosome-trans-Golgi network trafficking.

Jin, Fengyan; Hagemann, Nina; Brockmeier, Ulf; Schäfer, Simon T; Zechariah, Anil; Hermann, Dirk M.

Angiogenesis; 16(3): 625-37, 2013 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-23429999

10.

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.

Panaretakis, Theocharis; Kepp, Oliver; Brockmeier, Ulf; Tesniere, Antoine; Bjorklund, Ann-Charlotte; Chapman, Daniel C; Durchschlag, Michael; Joza, Nicholas; Pierron, Gérard; van Endert, Peter; Yuan, Junying; Zitvogel, Laurence; Madeo, Frank; Williams, David B; Kroemer, Guido.

EMBO J; 28(5): 578-90, 2009 Mar 04.

Artículo en Inglés | MEDLINE | ID: mdl-19165151

11.

Structural and functional relationships between the lectin and arm domains of calreticulin.

Pocanschi, Cosmin L; Kozlov, Guennadi; Brockmeier, Ulf; Brockmeier, Achim; Williams, David B; Gehring, Kalle.

J Biol Chem; 286(31): 27266-77, 2011 Aug 05.

Artículo en Inglés | MEDLINE | ID: mdl-21652723

12.

Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism.

Doeppner, Thorsten R; Coman, Cristin; Burdusel, Daiana; Ancuta, Diana-Larisa; Brockmeier, Ulf; Pirici, Daniel Nicolae; Yaoyun, Kuang; Hermann, Dirk M; Popa-Wagner, Aurel.

Aging (Albany NY); 14(10): 4195-4210, 2022 05 23.

Artículo en Inglés | MEDLINE | ID: mdl-35609021

13.

Stabilisation and knockdown of HIF--two distinct ways comparably important in radiotherapy.

Ströfer, Mareike; Jelkmann, Wolfgang; Metzen, Eric; Brockmeier, Ulf; Dunst, Jürgen; Depping, Reinhard.

Cell Physiol Biochem; 28(5): 805-12, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-22178933

14.

Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis.

Küper, Alina; Baumann, Jennifer; Göpelt, Kirsten; Baumann, Melanie; Sänger, Christopher; Metzen, Eric; Kranz, Philip; Brockmeier, Ulf.

Cell Death Dis; 12(1): 82, 2021 01 13.

Artículo en Inglés | MEDLINE | ID: mdl-33441543

15.

In oxygen-deprived tumor cells ERp57 provides radioprotection and ensures proliferation via c-Myc, PLK1 and the AKT pathway.

Ocklenburg, Tobias; Neumann, Fabian; Wolf, Alexandra; Vogel, Julia; Göpelt, Kirsten; Baumann, Melanie; Baumann, Jennifer; Kranz, Philip; Metzen, Eric; Brockmeier, Ulf.

Sci Rep; 11(1): 7199, 2021 03 30.

Artículo en Inglés | MEDLINE | ID: mdl-33785835

16.

Improvement of Sec-dependent secretion of a heterologous model protein in Bacillus subtilis by saturation mutagenesis of the N-domain of the AmyE signal peptide.

Caspers, Michael; Brockmeier, Ulf; Degering, Christian; Eggert, Thorsten; Freudl, Roland.

Appl Microbiol Biotechnol; 86(6): 1877-85, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20077115

17.

Tumor cells rely on the thiol oxidoreductase PDI for PERK signaling in order to survive ER stress.

Kranz, Philip; Sänger, Christopher; Wolf, Alexandra; Baumann, Jennifer; Metzen, Eric; Baumann, Melanie; Göpelt, Kirsten; Brockmeier, Ulf.

Sci Rep; 10(1): 15299, 2020 09 17.

Artículo en Inglés | MEDLINE | ID: mdl-32943707

18.

Systematic screening of all signal peptides from Bacillus subtilis: a powerful strategy in optimizing heterologous protein secretion in Gram-positive bacteria.

Brockmeier, Ulf; Caspers, Michael; Freudl, Roland; Jockwer, Alexander; Noll, Thomas; Eggert, Thorsten.

J Mol Biol; 362(3): 393-402, 2006 Sep 22.

Artículo en Inglés | MEDLINE | ID: mdl-16930615

19.

PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR).

Kranz, Philip; Neumann, Fabian; Wolf, Alexandra; Classen, Fabian; Pompsch, Mosche; Ocklenburg, Tobias; Baumann, Jennifer; Janke, Kirsten; Baumann, Melanie; Goepelt, Kirsten; Riffkin, Helena; Metzen, Eric; Brockmeier, Ulf.

Cell Death Dis; 8(8): e2986, 2017 08 10.

Artículo en Inglés | MEDLINE | ID: mdl-28796255

20.

Dissecting VHL-associated pathologies.

Metzen, Eric; Brockmeier, Ulf.

Blood; 113(25): 6273-4, 2009 Jun 18.

Artículo en Inglés | MEDLINE | ID: mdl-19541835

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