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1.

The interferon landscape along the respiratory tract impacts the severity of COVID-19.

Sposito, Benedetta; Broggi, Achille; Pandolfi, Laura; Crotta, Stefania; Clementi, Nicola; Ferrarese, Roberto; Sisti, Sofia; Criscuolo, Elena; Spreafico, Roberto; Long, Jaclyn M; Ambrosi, Alessandro; Liu, Enju; Frangipane, Vanessa; Saracino, Laura; Bozzini, Sara; Marongiu, Laura; Facchini, Fabio A; Bottazzi, Andrea; Fossali, Tommaso; Colombo, Riccardo; Clementi, Massimo; Tagliabue, Elena; Chou, Janet; Pontiroli, Antonio E; Meloni, Federica; Wack, Andreas; Mancini, Nicasio; Zanoni, Ivan.

Cell; 184(19): 4953-4968.e16, 2021 09 16.

Artículo en Inglés | MEDLINE | ID: mdl-34492226

2.

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

Harb, Hani; Benamar, Mehdi; Lai, Peggy S; Contini, Paola; Griffith, Jason W; Crestani, Elena; Schmitz-Abe, Klaus; Chen, Qian; Fong, Jason; Marri, Luca; Filaci, Gilberto; Del Zotto, Genny; Pishesha, Novalia; Kolifrath, Stephen; Broggi, Achille; Ghosh, Sreya; Gelmez, Metin Yusuf; Oktelik, Fatma Betul; Cetin, Esin Aktas; Kiykim, Ayca; Kose, Murat; Wang, Ziwei; Cui, Ye; Yu, Xu G; Li, Jonathan Z; Berra, Lorenzo; Stephen-Victor, Emmanuel; Charbonnier, Louis-Marie; Zanoni, Ivan; Ploegh, Hidde; Deniz, Gunnur; De Palma, Raffaele; Chatila, Talal A.

Immunity; 54(6): 1186-1199.e7, 2021 06 08.

Artículo en Inglés | MEDLINE | ID: mdl-33915108

3.

IFN-λ suppresses intestinal inflammation by non-translational regulation of neutrophil function.

Broggi, Achille; Tan, Yunhao; Granucci, Francesca; Zanoni, Ivan.

Nat Immunol; 18(10): 1084-1093, 2017 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-28846084

4.

Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis.

Millet, Virginie; Gensollen, Thomas; Maltese, Michael; Serrero, Melanie; Lesavre, Nathalie; Bourges, Christophe; Pitaval, Christophe; Cadra, Sophie; Chasson, Lionel; Vu Man, Thien Phong; Masse, Marion; Martinez-Garcia, Juan Jose; Tranchida, Fabrice; Shintu, Laetitia; Mostert, Konrad; Strauss, Erick; Lepage, Patricia; Chamaillard, Mathias; Broggi, Achille; Peyrin-Biroulet, Laurent; Grimaud, Jean-Charles; Naquet, Philippe; Galland, Franck.

Gut; 72(6): 1115-1128, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36175116

5.

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence.

Liu, Ning-Ning; Uppuluri, Priya; Broggi, Achille; Besold, Angelique; Ryman, Kicki; Kambara, Hiroto; Solis, Norma; Lorenz, Viola; Qi, Wanjun; Acosta-Zaldívar, Maikel; Emami, S Noushin; Bao, Bin; An, Dingding; Bonilla, Francisco A; Sola-Visner, Martha; Filler, Scott G; Luo, Hongbo R; Engström, Ylva; Ljungdahl, Per Olof; Culotta, Valeria C; Zanoni, Ivan; Lopez-Ribot, Jose L; Köhler, Julia R.

PLoS Pathog; 14(7): e1007076, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-30059535

6.

Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells.

Vitali, Caterina; Mingozzi, Francesca; Broggi, Achille; Barresi, Simona; Zolezzi, Francesca; Bayry, Jagadeesh; Raimondi, Giorgio; Zanoni, Ivan; Granucci, Francesca.

Blood; 120(6): 1237-45, 2012 Aug 09.

Artículo en Inglés | MEDLINE | ID: mdl-22760781

7.

Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation.

Poli, Valentina; Pui-Yan Ma, Victor; Di Gioia, Marco; Broggi, Achille; Benamar, Mehdi; Chen, Qian; Mazitschek, Ralph; Haggarty, Stephen J; Chatila, Talal A; Karp, Jeffrey M; Zanoni, Ivan.

iScience; 24(11): 103256, 2021 Nov 19.

Artículo en Inglés | MEDLINE | ID: mdl-34761180

8.

Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.

Sposito, Benedetta; Broggi, Achille; Pandolfi, Laura; Crotta, Stefania; Ferrarese, Roberto; Sisti, Sofia; Clementi, Nicola; Ambrosi, Alessandro; Liu, Enju; Frangipane, Vanessa; Saracino, Laura; Marongiu, Laura; Facchini, Fabio A; Bottazzi, Andrea; Fossali, Tommaso; Colombo, Riccardo; Clementi, Massimo; Tagliabue, Elena; Pontiroli, Antonio E; Meloni, Federica; Wack, Andreas; Mancini, Nicasio; Zanoni, Ivan.

bioRxiv; 2021 Mar 30.

Artículo en Inglés | MEDLINE | ID: mdl-33821280

9.

Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion.

Broggi, Achille; Granucci, Francesca; Zanoni, Ivan.

J Exp Med; 217(1)2020 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-31821443

10.

Type III interferons disrupt the lung epithelial barrier upon viral recognition.

Broggi, Achille; Ghosh, Sreya; Sposito, Benedetta; Spreafico, Roberto; Balzarini, Fabio; Lo Cascio, Antonino; Clementi, Nicola; De Santis, Maria; Mancini, Nicasio; Granucci, Francesca; Zanoni, Ivan.

Science; 369(6504): 706-712, 2020 08 07.

Artículo en Inglés | MEDLINE | ID: mdl-32527925

11.

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs.

Zanoni, Ivan; Granucci, Francesca; Broggi, Achille.

Front Immunol; 8: 1661, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-29234323

12.

Editorial: Type III interferons: Emerging roles beyond antiviral barrier defense.

Boulant, Steeve; Forero, Adriana; Santer, Deanna M; Broggi, Achille.

Front Immunol; 13: 1030812, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36189214

13.

Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems.

Santus, William; Barresi, Simona; Mingozzi, Francesca; Broggi, Achille; Orlandi, Ivan; Stamerra, Giulia; Vai, Marina; Martorana, Alessandra M; Polissi, Alessandra; Köhler, Julia R; Liu, Ningning; Zanoni, Ivan; Granucci, Francesca.

Sci Immunol; 2(15)2017 Sep 22.

Artículo en Inglés | MEDLINE | ID: mdl-28939652

14.

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions.

Broggi, Achille; Cigni, Clara; Zanoni, Ivan; Granucci, Francesca.

J Vis Exp; (110): e52589, 2016 Apr 20.

Artículo en Inglés | MEDLINE | ID: mdl-27166881

15.

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells.

Zanoni, Ivan; Tan, Yunhao; Di Gioia, Marco; Broggi, Achille; Ruan, Jianbin; Shi, Jianjin; Donado, Carlos A; Shao, Feng; Wu, Hao; Springstead, James R; Kagan, Jonathan C.

Science; 352(6290): 1232-6, 2016 Jun 03.

Artículo en Inglés | MEDLINE | ID: mdl-27103670

16.

Microbe- and danger-induced inflammation.

Broggi, Achille; Granucci, Francesca.

Mol Immunol; 63(2): 127-33, 2015 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-25037632

17.

Migratory conventional dendritic cells in the induction of peripheral T cell tolerance.

Broggi, Achille; Zanoni, Ivan; Granucci, Francesca.

J Leukoc Biol; 94(5): 903-11, 2013 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-23898045

18.

Systemically administered DNA and fowlpox recombinants expressing four vaccinia virus genes although immunogenic do not protect mice against the highly pathogenic IHD-J vaccinia strain.

Bissa, Massimiliano; Pacchioni, Sole Maria; Zanotto, Carlo; De Giuli Morghen, Carlo; Illiano, Elena; Granucci, Francesca; Zanoni, Ivan; Broggi, Achille; Radaelli, Antonia.

Virus Res; 178(2): 374-82, 2013 Dec 26.

Artículo en Inglés | MEDLINE | ID: mdl-24050999

19.

IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions.

Zanoni, Ivan; Spreafico, Roberto; Bodio, Caterina; Di Gioia, Marco; Cigni, Clara; Broggi, Achille; Gorletta, Tatiana; Caccia, Michele; Chirico, Giuseppe; Sironi, Laura; Collini, Maddalena; Colombo, Mario P; Garbi, Natalio; Granucci, Francesca.

Cell Rep; 4(6): 1235-49, 2013 Sep 26.

Artículo en Inglés | MEDLINE | ID: mdl-24055061

20.

Similarities and differences of innate immune responses elicited by smooth and rough LPS.

Zanoni, Ivan; Bodio, Caterina; Broggi, Achille; Ostuni, Renato; Caccia, Michele; Collini, Maddalena; Venkatesh, Aparna; Spreafico, Roberto; Capuano, Giusy; Granucci, Francesca.

Immunol Lett; 142(1-2): 41-7, 2012 Feb 29.

Artículo en Inglés | MEDLINE | ID: mdl-22207037

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