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1.
Efficacy and Safety of Ornithine Phenylacetate for Treating Overt Hepatic Encephalopathy in a Randomized Trial.
Clin Gastroenterol Hepatol;
19(12): 2626-2635.e7, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33069881
2.
Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia.
Hepatology;
67(3): 1003-1013, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29080224
3.
Finding unrecognized information in overactive bladder clinical trial data: a new approach to understanding placebo and treatment effects.
Neurourol Urodyn;
32(4): 308-13, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23001509
4.
OCE-205 in rats and non-human primates: Pharmacokinetic and pharmacodynamic analysis.
Curr Res Pharmacol Drug Discov;
5: 100163, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37608843
5.
OCE-205, a Selective V1a Partial Agonist, Reduces Portal Pressure in Rat Models of Portal Hypertension.
J Exp Pharmacol;
15: 279-290, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37469992
6.
OCE-205, A Novel, Selective Vasopressin Receptor Mixed Agonist-Antagonist: Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics from a Phase 1 Study in Healthy Volunteers.
Clin Drug Investig;
43(9): 709-717, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37606870
7.
Partial vasopressin 1a receptor agonism reduces portal hypertension and hyperaldosteronism and induces a powerful diuretic and natriuretic effect in rats with cirrhosis and ascites.
Biomed Pharmacother;
165: 115116, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37418980
8.
A randomized, double-blind, placebo-controlled study assessing the safety and tolerability of regadenoson in subjects with asthma or chronic obstructive pulmonary disease.
J Nucl Cardiol;
19(4): 681-92, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22484721
9.
A randomized, double-blind, placebo-controlled study of the safety and tolerance of regadenoson in subjects with stage 3 or 4 chronic kidney disease.
J Nucl Cardiol;
19(2): 319-29, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22259009
10.
Pharmacokinetics/pharmacodynamics of L-ornithine phenylacetate in overt hepatic encephalopathy and the effect of plasma ammonia concentration reduction on clinical outcomes.
Clin Transl Sci;
15(6): 1449-1459, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35238476
11.
Effect of caffeine on SPECT myocardial perfusion imaging during regadenoson pharmacologic stress: a prospective, randomized, multicenter study.
Int J Cardiovasc Imaging;
30(5): 979-89, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24737255
12.
Industry perspective on the medical risk of visible particles in injectable drug products.
PDA J Pharm Sci Technol;
69(1): 123-39, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25691720
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