Clomipramine compared with pentazocine as a unique treatment in postoperative pain.

Forty patients who underwent laparotomy for hysterectomy were administered either clomipramine or pentazocine for the treatment of postoperative pain. Both drugs were similarly effective during the eight hours of observation. The results of this study indicate that clomipramine, often used in chronic pain as an adjuvant drug, exerts as well as analgesic effect in acute pain.