1.
Bioorg Med Chem Lett
; 22(7): 2497-502, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-22405833
RESUMEN
A novel class of DGAT1 inhibitors containing a thiadiazole core has been discovered. Chemical optimization lead to inhibitors of human DGAT1 with an appropriate ADME profile and that show in vivo activity in target tissues.