Detalles de la búsqueda
1.
Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage.
Toxicol Appl Pharmacol;
334: 8-17, 2017 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28867438
2.
Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin.
Acta Crystallogr D Biol Crystallogr;
71(Pt 10): 2066-78, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26457430
3.
Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib.
Biochimie;
207: 1-10, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36403756
4.
Increased Cholinergic Tone Causes Pre-synaptic Neuromuscular Degeneration and is Associated with Impaired Diaphragm Function.
Neuroscience;
460: 31-42, 2021 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33548369
5.
Neutralization of a bothropic PLA2-like protein by caftaric acid, a novel potent inhibitor of ophidian myotoxicity.
Biochimie;
170: 163-172, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-31978419
6.
Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches.
Sci Rep;
9(1): 510, 2019 01 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30679550
7.
Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins.
Biochim Biophys Acta Gen Subj;
1862(12): 2728-2737, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30251662
8.
Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.
Sci Rep;
8(1): 10317, 2018 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29985425
9.
Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties.
J Venom Anim Toxins Incl Trop Dis;
24: 22, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30181737
10.
Neuromuscular synapse degeneration without muscle function loss in the diaphragm of a murine model for Huntington's Disease.
Neurochem Int;
116: 30-42, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29530757
11.
Neutralization of snake venom phospholipase A2 toxins by aqueous extract of Casearia sylvestris (Flacourtiaceae) in mouse neuromuscular preparation.
J Ethnopharmacol;
112(3): 490-7, 2007 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-17540522
12.
Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism.
Sci Rep;
7: 43885, 2017 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28256632
13.
Influence of temperature upon paralyzing and myotoxic effects of bothropstoxin-I on mouse neuromuscular preparations.
Chem Biol Interact;
151(2): 95-100, 2005 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15698581
14.
Biological characterization of the Amazon coral Micrurus spixii snake venom: Isolation of a new neurotoxic phospholipase A2.
Toxicon;
103: 1-11, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26095535
15.
Antagonism of myotoxic and paralyzing activities of bothropstoxin-I by suramin.
Toxicon;
42(4): 373-9, 2003 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14505937
16.
Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A2-like.
Toxicon;
72: 52-63, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23810946
17.
Bothropstoxin-I reduces evoked acetylcholine release from rat motor nerve terminals: radiochemical and real-time video-microscopy studies.
Toxicon;
61: 16-25, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23142504
18.
Structural and phylogenetic studies with MjTX-I reveal a multi-oligomeric toxin--a novel feature in Lys49-PLA2s protein class.
PLoS One;
8(4): e60610, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23573271
19.
Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties
J. venom. anim. toxins incl. trop. dis;
24: 1-11, 2018. ilus, tab, graf
Artículo
en Inglés
| LILACS, VETINDEX | ID: biblio-1484757
20.
Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties
J. venom. anim. toxins incl. trop. dis;
24: 22, 2018. ilus, graf
Artículo
en Inglés
| LILACS | ID: biblio-954854