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1.

Physiologically Important Electrolytes as Regulators of TDP-43 Aggregation and Droplet-Phase Behavior.

Sun, Yulong; Medina Cruz, Alison; Hadley, Kevin C; Galant, Natalie J; Law, Ryan; Vernon, Robert M; Morris, Vanessa K; Robertson, Janice; Chakrabartty, Avijit.

Biochemistry; 58(6): 590-607, 2019 02 12.

Artículo en Inglés | MEDLINE | ID: mdl-30489059

2.

Phase to Phase with TDP-43.

Sun, Yulong; Chakrabartty, Avijit.

Biochemistry; 56(6): 809-823, 2017 Feb 14.

Artículo en Inglés | MEDLINE | ID: mdl-28112502

3.

Transthyretin amyloidosis: an under-recognized neuropathy and cardiomyopathy.

Galant, Natalie J; Westermark, Per; Higaki, Jeffrey N; Chakrabartty, Avijit.

Clin Sci (Lond); 131(5): 395-409, 2017 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-28213611

4.

Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.

Xiao, Shangxi; Sanelli, Teresa; Chiang, Helen; Sun, Yulong; Chakrabartty, Avijit; Keith, Julia; Rogaeva, Ekaterina; Zinman, Lorne; Robertson, Janice.

Acta Neuropathol; 130(1): 49-61, 2015 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-25788357

5.

Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.

Weichert, Anna; Besemer, Anna S; Liebl, Martina; Hellmann, Nadja; Koziollek-Drechsler, Ingrid; Ip, Philbert; Decker, Heinz; Robertson, Janice; Chakrabartty, Avijit; Behl, Christian; Clement, Albrecht M.

Neurobiol Dis; 62: 479-88, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24200866

6.

"Structural characterization of the minimal segment of TDP-43 competent for aggregation".

Mompeán, Miguel; Buratti, Emanuele; Guarnaccia, Corrado; Brito, Rui M M; Chakrabartty, Avijit; Baralle, Francisco E; Laurents, Douglas V.

Arch Biochem Biophys; 545: 53-62, 2014 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-24440310

7.

Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation.

Mompeán, Miguel; Chakrabartty, Avijit; Buratti, Emanuele; Laurents, Douglas V.

PLoS Biol; 14(4): e1002447, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-27096426

8.

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

Rakhit, Rishi; Robertson, Janice; Vande Velde, Christine; Horne, Patrick; Ruth, Deborah M; Griffin, Jennifer; Cleveland, Don W; Cashman, Neil R; Chakrabartty, Avijit.

Nat Med; 13(6): 754-9, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17486090

9.

Targeting of monomer/misfolded SOD1 as a therapeutic strategy for amyotrophic lateral sclerosis.

Liu, Hsueh-Ning; Tjostheim, Sonja; Dasilva, Kevin; Taylor, David; Zhao, Beibei; Rakhit, Rishi; Brown, Mary; Chakrabartty, Avijit; McLaurin, Joanne; Robertson, Janice.

J Neurosci; 32(26): 8791-9, 2012 Jun 27.

Artículo en Inglés | MEDLINE | ID: mdl-22745481

10.

Protein misfolding in the late-onset neurodegenerative diseases: common themes and the unique case of amyotrophic lateral sclerosis.

Mulligan, Vikram Khipple; Chakrabartty, Avijit.

Proteins; 81(8): 1285-303, 2013 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-23508986

11.

Structure of a simplified ß-hairpin and its ATP complex.

Diez-García, Fernando; Pantoja-Uceda, David; Jiménez, Ma Ángeles; Chakrabartty, Avijit; Laurents, Douglas V.

Arch Biochem Biophys; 537(1): 62-71, 2013 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-23811197

12.

Prion disease susceptibility is affected by beta-structure folding propensity and local side-chain interactions in PrP.

Khan, M Qasim; Sweeting, Braden; Mulligan, Vikram Khipple; Arslan, Pharhad Eli; Cashman, Neil R; Pai, Emil F; Chakrabartty, Avijit.

Proc Natl Acad Sci U S A; 107(46): 19808-13, 2010 Nov 16.

Artículo en Inglés | MEDLINE | ID: mdl-21041683

13.

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization.

Ceccarelli, Derek F; Laister, Rob C; Mulligan, Vikram Khipple; Kean, Michelle J; Goudreault, Marilyn; Scott, Ian C; Derry, W Brent; Chakrabartty, Avijit; Gingras, Anne-Claude; Sicheri, Frank.

J Biol Chem; 286(28): 25056-64, 2011 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-21561863

14.

An Arg-rich putative prebiotic protein is as stable as its Lys-rich variant.

Diez-García, Fernando; Chakrabartty, Avijit; González, Carlos; Laurents, Douglas V.

Arch Biochem Biophys; 528(2): 118-26, 2012 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-23022061

15.

Analyzing complicated protein folding kinetics rapidly by analytical Laplace inversion using a Tikhonov regularization variant.

Mulligan, Vikram Khipple; Hadley, Kevin Charles; Chakrabartty, Avijit.

Anal Biochem; 421(1): 181-90, 2012 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-22119751

16.

Conformation specificity and arene binding in a peptide composed only of Lys, Ile, Ala and Gly.

Diez-García, Fernando; Gómez-Pinto, Irene; Chakrabartty, Avijit; González, Carlos; Laurents, Douglas V.

Eur Biophys J; 41(1): 63-72, 2012 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-22038076

17.

Relative and regional stabilities of the hamster, mouse, rabbit, and bovine prion proteins toward urea unfolding assessed by nuclear magnetic resonance and circular dichroism spectroscopies.

Julien, Olivier; Chatterjee, Subhrangsu; Bjorndahl, Trent C; Sweeting, Braden; Acharya, Sandipta; Semenchenko, Valentyna; Chakrabartty, Avijit; Pai, Emil F; Wishart, David S; Sykes, Brian D; Cashman, Neil R.

Biochemistry; 50(35): 7536-45, 2011 Sep 06.

Artículo en Inglés | MEDLINE | ID: mdl-21800884

18.

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form.

Kerman, Aaron; Liu, Hsueh-Ning; Croul, Sidney; Bilbao, Juan; Rogaeva, Ekaterina; Zinman, Lorne; Robertson, Janice; Chakrabartty, Avijit.

Acta Neuropathol; 119(3): 335-44, 2010 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-20111867

19.

Putative one-pot prebiotic polypeptides with ribonucleolytic activity.

López-Alonso, Jorge P; Pardo-Cea, Miguel A; Gómez-Pinto, Irene; Fernández, Irene; Chakrabartty, Avijit; Pedroso, Enrique; González, Carlos; Laurents, Douglas V.

Chemistry; 16(18): 5314-23, 2010 May 10.

Artículo en Inglés | MEDLINE | ID: mdl-20232309

20.

Two distinct conformations of Abeta aggregates on the surface of living PC12 cells.

Bateman, David A; Chakrabartty, Avijit.

Biophys J; 96(10): 4260-7, 2009 May 20.

Artículo en Inglés | MEDLINE | ID: mdl-19450496

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