Detalles de la búsqueda
1.
Mitophagy in Alzheimer's disease: Molecular defects and therapeutic approaches.
Mol Psychiatry;
28(1): 202-216, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35665766
2.
The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aß production.
Cell Mol Life Sci;
80(4): 97, 2023 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36930302
3.
Dipeptidyl peptidase 4 contributes to Alzheimer's disease-like defects in a mouse model and is increased in sporadic Alzheimer's disease brains.
J Biol Chem;
297(2): 100963, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34265307
4.
Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer's disease (AD) mouse model and is increased at early stage in sporadic AD brain.
Acta Neuropathol;
141(6): 823-839, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33881611
5.
Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains.
Acta Neuropathol;
141(1): 39-65, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33079262
6.
Molecular Dysfunctions of Mitochondria-Associated Membranes (MAMs) in Alzheimer's Disease.
Int J Mol Sci;
21(24)2020 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33327665
7.
Amyloid ß production is regulated by ß2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.
J Biol Chem;
292(24): 10153-10168, 2017 06 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-28476886
8.
Epidermal TRPM8 channel isoform controls the balance between keratinocyte proliferation and differentiation in a cold-dependent manner.
Proc Natl Acad Sci U S A;
112(26): E3345-54, 2015 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-26080404
9.
Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Acta Neuropathol;
134(5): 749-767, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28631094
10.
Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress.
Mol Cell;
32(5): 641-51, 2008 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-19061639
11.
Ryanodine receptor blockade reduces amyloid-ß load and memory impairments in Tg2576 mouse model of Alzheimer disease.
J Neurosci;
32(34): 11820-34, 2012 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22915123
12.
Nuclear factor-κB regulates ßAPP and ß- and γ-secretases differently at physiological and supraphysiological Aß concentrations.
J Biol Chem;
287(29): 24573-84, 2012 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-22654105
13.
Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer's disease patients are associated with cognitive impairment.
Transl Psychiatry;
13(1): 54, 2023 02 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36788216
14.
Identification of CANT1 mutations in Desbuquois dysplasia.
Am J Hum Genet;
85(5): 706-10, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19853239
15.
Nuclear factor-κB regulates ßAPP and ß- and γ-secretases differently at physiological and supraphysiological Aß concentrations.
J Biol Chem;
290(50): 29758, 2015 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26657754
16.
Calcium Signalling in Alzheimer's Disease: From Pathophysiological Regulation to Therapeutic Approaches.
Cells;
10(1)2021 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33445705
17.
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.
Autophagy;
17(12): 4363-4385, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34030589
18.
Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimer's Disease.
Cells;
9(12)2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33271984
19.
Targeting Post-Translational Remodeling of Ryanodine Receptor: A New Track for Alzheimer's Disease Therapy?
Curr Alzheimer Res;
17(4): 313-323, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32096743
20.
Upregulation of the Sarco-Endoplasmic Reticulum Calcium ATPase 1 Truncated Isoform Plays a Pathogenic Role in Alzheimer's Disease.
Cells;
8(12)2019 11 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-31795302