Detalles de la búsqueda
1.
Fungal Ball in the Urinary Bladder.
N Engl J Med;
387(1): e2, 2022 07 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35775997
2.
Repeated centrifuging and washing concentrates bacterial samples in peritoneal dialysis for optimal culture: an original article.
BMC Microbiol;
20(1): 365, 2020 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-33246404
3.
Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.
J Biol Chem;
290(17): 11061-74, 2015 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-25762719
4.
Discovery of furo[2,3-d][1,3]thiazinamines as beta amyloid cleaving enzyme-1 (BACE1) inhibitors.
Bioorg Med Chem Lett;
26(23): 5729-5731, 2016 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27816517
5.
Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2).
Bioorg Med Chem Lett;
25(19): 4265-9, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26320619
6.
Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases.
Bioorg Med Chem Lett;
24(9): 2206-11, 2014 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24685542
7.
Gut microbiota and clinical response to immune checkpoint inhibitor therapy in patients with advanced cancer.
Biomed J;
: 100698, 2024 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38280521
8.
Nutritional status of vegetarians on maintenance haemodialysis.
Nephrology (Carlton);
16(6): 582-7, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21457399
9.
Using yeast surface display to engineer a soluble and crystallizable construct of hematopoietic progenitor kinase 1 (HPK1).
Acta Crystallogr F Struct Biol Commun;
77(Pt 1): 22-28, 2021 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33439152
10.
Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase.
Bioorg Med Chem Lett;
20(17): 5027-30, 2010 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20675137
11.
Synthesis and structure-activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARalpha selective activators- PPARalpha and PPARgamma selectivity modulation.
Bioorg Med Chem Lett;
20(9): 2933-7, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20356736
12.
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches.
J Med Chem;
63(23): 15050-15071, 2020 12 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33261314
13.
Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists.
Bioorg Med Chem Lett;
19(5): 1451-6, 2009 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19201606
14.
Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2).
J Med Chem;
62(20): 8953-8972, 2019 10 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31314518
15.
Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors.
ACS Med Chem Lett;
10(3): 383-388, 2019 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30891145
16.
Discovery of azetidinone acids as conformationally-constrained dual PPARalpha/gamma agonists.
Bioorg Med Chem Lett;
18(6): 1939-44, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18291645
17.
Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine ß-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors.
J Med Chem;
59(18): 8593-600, 2016 09 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27559936
18.
Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain Aß Reduction in Rodents.
ACS Med Chem Lett;
7(3): 271-6, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26985314
19.
Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177).
J Med Chem;
59(17): 7915-35, 2016 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27531604
20.
Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist.
ACS Med Chem Lett;
7(6): 590-4, 2016 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27326332