Detalles de la búsqueda
1.
The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia.
Blood;
142(7): 629-642, 2023 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37172201
2.
Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Blood;
138(23): 2313-2326, 2021 12 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34110416
3.
NG2 Proteoglycan Ablation Reduces Foam Cell Formation and Atherogenesis via Decreased Low-Density Lipoprotein Retention by Synthetic Smooth Muscle Cells.
Arterioscler Thromb Vasc Biol;
36(1): 49-59, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26543095
4.
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nat Commun;
15(1): 482, 2024 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38228616
5.
Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan.
Breast Cancer Res;
14(2): R67, 2012 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-22531600
6.
Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs.
ACS Med Chem Lett;
13(3): 475-482, 2022 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35300081
7.
ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia.
Blood Cancer Discov;
3(3): 240-263, 2022 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35247902
8.
Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord.
J Neuroinflammation;
8: 158, 2011 Nov 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-22078261
9.
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.
Blood;
113(9): 1992-2002, 2009 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19060246
10.
Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators.
J Med Chem;
64(11): 7296-7311, 2021 06 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34042448
11.
Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth.
Prostate;
70(2): 190-9, 2010 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19790232
12.
Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment.
Proc Natl Acad Sci U S A;
104(26): 10888-93, 2007 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17578909
13.
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.
Nat Genet;
48(12): 1481-1489, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27776115
14.
LFIRE-1/HFREP-1, a liver-specific gene, is frequently downregulated and has growth suppressor activity in hepatocellular carcinoma.
Oncogene;
23(10): 1939-49, 2004 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-14981537
15.
Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.
Cancer Cell;
28(3): 343-56, 2015 Sep 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26321221
16.
Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
PLoS One;
8(12): e82684, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24340053
17.
Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity.
PLoS One;
7(1): e30637, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22295099
18.
Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.
Cell Metab;
14(2): 219-30, 2011 Aug 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-21803292
19.
Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts.
Cell Cycle;
6(23): 2877-83, 2007 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18156802
20.
Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation.
J Biol Chem;
282(39): 28683-28690, 2007 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-17681947