1.
Org Biomol Chem
; 12(29): 5458-63, 2014 Aug 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-24942670
RESUMEN
A series of phosphaisocoumarin amidates were synthesized for the first time via DIBAL-H-mediated direct amidation of phosphaisocoumarin esters under mild conditions in good to excellent yields. The present reaction showed high selectivity. In each case, the phostone ring was intact and only the exocyclic ethoxy group was amidated. A plausible mechanism of the reaction was provided.