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1.
Use of pharmacodynamic modeling for Bayesian information borrowing in pediatric clinical trials.
J Biopharm Stat;
33(6): 726-736, 2023 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36524777
2.
Concentration-QT modelling shows no evidence of clinically significant QT interval prolongation with capivasertib at expected therapeutic concentrations.
Br J Clin Pharmacol;
88(2): 858-864, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34309049
3.
Structural identifiability for mathematical pharmacology: models of myelosuppression.
J Pharmacokinet Pharmacodyn;
45(1): 79-90, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-29396780
4.
Characterization of the disposition of fostamatinib in Japanese subjects including pharmacokinetic assessment in dry blood spots: results from two phase I clinical studies.
Eur J Clin Pharmacol;
72(1): 61-71, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26490353
5.
The design and analysis of parallel experiments to produce structurally identifiable models.
J Pharmacokinet Pharmacodyn;
40(1): 93-100, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23300030
6.
Supporting Prospective Pregnancy Trials via Modeling and Simulation: Lessons From the Past and Recommendations for the Future.
J Clin Pharmacol;
63 Suppl 1: S51-S61, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37317497
7.
Pediatric oncology drug development and dosage optimization.
Front Oncol;
13: 1235947, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38348118
8.
Moving Toward a Question-Centric Approach for Regulatory Decision Making in the Context of Drug Assessment.
Clin Pharmacol Ther;
114(1): 41-50, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36708100
9.
Cost effectiveness analyses of pharmacological treatments in heart failure.
Front Pharmacol;
13: 919974, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36133814
10.
Accelerating model-informed decisions for COVID-19 vaccine candidates using a model-based meta-analysis approach.
EBioMedicine;
84: 104264, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-36182824
11.
Epstein-Barr Virus Reactivation After Paediatric Haematopoietic Stem Cell Transplantation: Risk Factors and Sensitivity Analysis of Mathematical Model.
Front Immunol;
13: 903063, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35903096
12.
A meta-analysis of tumour response and relapse kinetics based on 34,881 patients: A question of cancer type, treatment and line of treatment.
Eur J Cancer;
150: 42-52, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33892406
13.
V2 ACHER: Visualization of complex trial data in pharmacometric analyses with covariates.
CPT Pharmacometrics Syst Pharmacol;
10(9): 1092-1106, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34242494
14.
Harnessing formulation and clinical pharmacology knowledge for efficient pediatric drug development: Overview and discussions from M-CERSI pediatric formulation workshop 2019.
Eur J Pharm Biopharm;
164: 66-74, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33878434
15.
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
Clin Cancer Res;
27(19): 5213-5224, 2021 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34301752
16.
Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis.
EBioMedicine;
73: 103651, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34775220
17.
Correction to: How is the Pharmaceutical Industry Structured to Optimize Pediatric Drug Development? Existing Pediatric Structure Models and Proposed Recommendations for Structural Enhancement.
Ther Innov Regul Sci;
54(5): 1085, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32865808
18.
Artificial Intelligence and Machine Learning Applied at the Point of Care.
Front Pharmacol;
11: 759, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32625083
19.
How is the Pharmaceutical Industry Structured to Optimize Pediatric Drug Development? Existing Pediatric Structure Models and Proposed Recommendations for Structural Enhancement.
Ther Innov Regul Sci;
54(5): 1076-1084, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32030690
20.
Proliferation and AKT Activity Biomarker Analyses after Capivasertib (AZD5363) Treatment of Patients with ER+ Invasive Breast Cancer (STAKT).
Clin Cancer Res;
26(7): 1574-1585, 2020 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31836609