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1.

SLC26A4-linked CEVA haplotype correlates with phenotype in patients with enlargement of the vestibular aqueduct.

Chao, Janet R; Chattaraj, Parna; Munjal, Tina; Honda, Keiji; King, Kelly A; Zalewski, Christopher K; Chien, Wade W; Brewer, Carmen C; Griffith, Andrew J.

BMC Med Genet; 20(1): 118, 2019 07 02.

Artículo en Inglés | MEDLINE | ID: mdl-31266487

2.

Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.

Isgrig, Kevin; Shteamer, Jack W; Belyantseva, Inna A; Drummond, Meghan C; Fitzgerald, Tracy S; Vijayakumar, Sarath; Jones, Sherri M; Griffith, Andrew J; Friedman, Thomas B; Cunningham, Lisa L; Chien, Wade W.

Mol Ther; 30(2): 975, 2022 Feb 02.

Artículo en Inglés | MEDLINE | ID: mdl-35063081

3.

Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.

Isgrig, Kevin; Shteamer, Jack W; Belyantseva, Inna A; Drummond, Meghan C; Fitzgerald, Tracy S; Vijayakumar, Sarath; Jones, Sherri M; Griffith, Andrew J; Friedman, Thomas B; Cunningham, Lisa L; Chien, Wade W.

Mol Ther; 25(3): 780-791, 2017 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-28254438

4.

Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice.

Chien, Wade W; Isgrig, Kevin; Roy, Soumen; Belyantseva, Inna A; Drummond, Meghan C; May, Lindsey A; Fitzgerald, Tracy S; Friedman, Thomas B; Cunningham, Lisa L.

Mol Ther; 24(1): 17-25, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26307667

5.

A CRISPR Way to Restore Hearing.

Chien, Wade W.

N Engl J Med; 378(13): 1255-1256, 2018 03 29.

Artículo en Inglés | MEDLINE | ID: mdl-29601257

6.

Hearing Loss after Round Window Surgery in Mice Is due to Middle Ear Effusion.

Zhu, Bovey Z; Saleh, Jasmine; Isgrig, Kevin T; Cunningham, Lisa L; Chien, Wade W.

Audiol Neurootol; 21(6): 356-364, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-28068659

7.

Gene therapy for sensorineural hearing loss.

Chien, Wade W; Monzack, Elyssa L; McDougald, Devin S; Cunningham, Lisa L.

Ear Hear; 36(1): 1-7, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25166629

8.

Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B.

Lau, Samantha C; Grati, Mhamed; Isgrig, Kevin; Sinan, Moaz; Calabro, Kaitlyn R; Zhu, Jianliang; Ishibashi, Yasuko; Ozgur, Zeynep; Wafa, Talah; Belyantseva, Inna A; Fitzgerald, Tracy; Friedman, Thomas B; Boye, Sanford L; Boye, Shannon E; Chien, Wade W.

Mol Ther Methods Clin Dev; 30: 534-545, 2023 Sep 14.

Artículo en Inglés | MEDLINE | ID: mdl-37693946

9.

GATA3 haploinsufficiency does not block allergic sensitization or atopic disease.

Lawrence, Monica G; Leiding, Jennifer W; Lyons, Jonathan J; Hsu, Amy P; Nelson, Celeste C; Jones, Nina; Fitzgerald, Alan; Chien, Wade W; Workman, Lisa; Platts-Mills, Thomas A; Brewer, Carmen; Gafni, Rachel I; Stone, Kelly D; Milner, Joshua D; Holland, Steven M.

J Allergy Clin Immunol; 137(2): 627-629.e2, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26282285

10.

AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency.

Isgrig, Kevin; Ishibashi, Yasuko; Lee, Hyun Jae; Zhu, Jianliang; Grati, Mhamed; Bennett, Jean; Griffith, Andrew J; Roux, Isabelle; Chien, Wade W.

Mol Ther Methods Clin Dev; 26: 371-383, 2022 Sep 08.

Artículo en Inglés | MEDLINE | ID: mdl-36034771

11.

Canal dehiscence.

Chien, Wade W; Carey, John P; Minor, Lloyd B.

Curr Opin Neurol; 24(1): 25-31, 2011 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-21124219

12.

Validation of a 3D-printed human temporal bone model for otology surgical skill training.

Chien, Wade W; da Cruz, Melville J; Francis, Howard W.

World J Otorhinolaryngol Head Neck Surg; 7(2): 88-93, 2021 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-33997717

13.

Adeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges.

Askew, Charles; Chien, Wade W.

Hear Res; 394: 107947, 2020 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-32247629

14.

Surgical Methods for Inner Ear Gene Delivery in Neonatal Mouse.

Isgrig, Kevin; Chien, Wade W.

Methods Mol Biol; 1937: 221-226, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30706399

15.

AAV2.7m8 is a powerful viral vector for inner ear gene therapy.

Isgrig, Kevin; McDougald, Devin S; Zhu, Jianliang; Wang, Hong Jun; Bennett, Jean; Chien, Wade W.

Nat Commun; 10(1): 427, 2019 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-30683875

16.

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse.

Isgrig, Kevin; Chien, Wade W.

J Vis Exp; (133)2018 03 02.

Artículo en Inglés | MEDLINE | ID: mdl-29553564

17.

Hearing loss associated with enlarged vestibular aqueduct and zero or one mutant allele of SLC26A4.

Rose, Jane; Muskett, Julie A; King, Kelly A; Zalewski, Christopher K; Chattaraj, Parna; Butman, John A; Kenna, Margaret A; Chien, Wade W; Brewer, Carmen C; Griffith, Andrew J.

Laryngoscope; 127(7): E238-E243, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-27859305

18.

Research Techniques Made Simple: The Application of CRISPR-Cas9 and Genome Editing in Investigative Dermatology.

Guitart, Joan Ramon; Johnson, Jodi L; Chien, Wade W.

J Invest Dermatol; 136(9): e87-e93, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27542298

19.

Racial Differences of Pigmentation in the Human Vestibular Organs.

Erbele, Isaac D; Lin, Frank R; Agrawal, Yuri; Francis, Howard W; Carey, John P; Chien, Wade W.

Otolaryngol Head Neck Surg; 155(3): 479-84, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27165682

20.

Use of Pericranial Flap Coverage in Cochlear Implantation of the Radical Cavity: Rationale, Technique, and Experience.

Nieman, Carrie L; Weinreich, Heather M; Sharon, Jeffrey D; Chien, Wade W; Francis, Howard W.

Otolaryngol Head Neck Surg; 155(3): 533-7, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-26980911

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SLC26A4-linked CEVA haplotype correlates with phenotype in patients with enlargement of the vestibular aqueduct.

Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.

Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.

Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice.

A CRISPR Way to Restore Hearing.

Hearing Loss after Round Window Surgery in Mice Is due to Middle Ear Effusion.

Gene therapy for sensorineural hearing loss.

Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B.

GATA3 haploinsufficiency does not block allergic sensitization or atopic disease.

AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency.

Canal dehiscence.

Validation of a 3D-printed human temporal bone model for otology surgical skill training.

Adeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges.

Surgical Methods for Inner Ear Gene Delivery in Neonatal Mouse.

AAV2.7m8 is a powerful viral vector for inner ear gene therapy.

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse.

Hearing loss associated with enlarged vestibular aqueduct and zero or one mutant allele of SLC26A4.

Research Techniques Made Simple: The Application of CRISPR-Cas9 and Genome Editing in Investigative Dermatology.

Racial Differences of Pigmentation in the Human Vestibular Organs.

Use of Pericranial Flap Coverage in Cochlear Implantation of the Radical Cavity: Rationale, Technique, and Experience.