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1.
PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA.
Mol Ther;
29(3): 1086-1101, 2021 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33221436
2.
Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform.
Bioorg Med Chem Lett;
24(23): 5450-4, 2014 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25454270
3.
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries.
Bioorg Med Chem Lett;
23(5): 1407-11, 2013 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23337601
4.
Rare case of coexisting ovarian Brenner tumour and ovarian stromal hyperplasia presenting with persistent endometrial hyperplasia following treatment with levonorgestrel-intrauterine system.
BMJ Case Rep;
15(12)2022 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36543369
5.
Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11ß-hydroxydehydrogenase 1 (11ß-HSD1).
Bioorg Med Chem Lett;
21(22): 6693-8, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21983444
6.
A selective cannabinoid-1 receptor antagonist, PF-95453, reduces body weight and body fat to a greater extent than pair-fed controls in obese monkeys.
J Pharmacol Exp Ther;
335(1): 103-13, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20605903
7.
Discovery of N-benzyl-2-[(4S)-4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]-N-isopropylacetamide, an orally active, gut-selective CCK1 receptor agonist for the potential treatment of obesity.
Bioorg Med Chem Lett;
20(22): 6797-801, 2010 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20851601
8.
Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy.
PLoS Curr;
92017 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28228973
9.
Galanin function in the central nervous system.
Curr Opin Drug Discov Devel;
9(5): 560-70, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17002216
10.
Potent histone deacetylase inhibitors derived from 4-(aminomethyl)-N-hydroxybenzamide with high selectivity for the HDAC6 isoform.
J Med Chem;
56(18): 7201-11, 2013 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23964961
11.
Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example.
ACS Med Chem Lett;
4(11): 1079-84, 2013 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900608
12.
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists.
ACS Med Chem Lett;
4(1): 63-8, 2013 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900564
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