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Int J Legal Med ; 133(3): 803-805, 2019 May.
Artículo en Inglés | MEDLINE | ID: mdl-30762220

RESUMEN

Performance of PowerPlex Fusion 6C kit (PP F6C) was assessed in 374 unrelated individuals belonging to Madhya Pradesh, an Indian state. The study evaluated the forensic parameters for the loci included in PP F6C Multiplex System. The combined discrimination power (CPD) and combined exclusion power (CPE) were 1 and 0.999999995, respectively, for all 23 autosomal STR loci. SE33 showed the greatest power of discrimination (0.990) in the studied population, whereas TPOX showed the lowest (0.843). The availability of three Y-STR loci in the Multiplex System is suitable for assessing male contribution and amelogenin deletion in a single Multiplex PCR simultaneously. The study also presents the first global report on polymorphism in the Indian population on SE 33 autosomal STR loci and PP Fusion 6C Multiplex System. The results revealed that the studied STR Multiplex System is highly polymorphic and suitable for forensic purposes.


Asunto(s)
Genética de Población , Repeticiones de Microsatélite , Reacción en Cadena de la Polimerasa Multiplex , Dermatoglifia del ADN , Frecuencia de los Genes , Humanos , India , Polimorfismo Genético
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