Cross-sectional household transmission study of Cryptosporidium shows that C. hominis infections are a key risk factor for spread.

BACKGROUND: Infection with the Cryptosporidium parasite causes over 4000 cases of diagnosed illness (cryptosporidiosis) in England and Wales each year. The incidence of sporadic disease has not been sufficiently established, and how frequently this arises from contact with other infected people is not well documented. This project aimed to explore potential transmission in the home and attempt to identify asymptomatic infections, which might play a role in transmission. Risk factors and characteristics associated with spread of infection in the home were described including any differences between Cryptosporidium species. METHODS: The study identified cryptosporidiosis cases from North West England and Wales over a year and invited them and their household to take part. Each household was sent a study pack containing study information and a questionnaire, and stool sample kits to provide samples from consenting household members. Cryptosporidium-positive stool samples, identified by immunofluorescence microscopy, were characterised using molecular methods to help describe any patterns of transmission. Characteristics of households with and without additional cases were described, and compared using odds ratios (OR) and a multivariable logistic regression identified independent risk factors for household transmission. Data collection ran for one year, beginning in September 2018 with an initial pilot phase. RESULTS: We enrolled 128 index cases and their households. Additional illness occurred in over a quarter of homes, each reporting an average of two additional cases. The majority of these were undiagnosed and unreported to surveillance. This burden was even greater in households where the index case was infected with C. hominis versus C. parvum, or the index case was under five years old, with mums and siblings most at risk of secondary infection. Only having an index case of C. hominis was independently associated with transmission in the multivariable model (OR 4.46; p = 0.01). CONCLUSIONS: Cryptosporidium was a considerable burden in the home. At-risk homes were those where the index was less than five years old and/or infected with C. hominis. Of particular risk were female caregivers and siblings. Hygiene advice should be specifically directed here. This work provides evidence for humans as sources of C. hominis infection and that person-person is a key pathway. We recommend that all stools submitted for the investigation of gastrointestinal pathogens are tested for Cryptosporidium to better capture cases, inclusion of speciation data in routine surveillance, and the consideration of specific clinical advice on prevention for high-risk homes.

A cross-sectional study of factors associated with regular dog walking and intention to walk the dog.

BACKGROUND: Dog walking is important for public health and dog welfare, yet some owners do not walk with their dogs regularly. This study examined factors associated with participation in regular dog walking and intention to dog walk, in order to inform physical activity interventions. METHODS: 191 dog-owning adults from a UK community were surveyed about their participation in dog walking, intention to dog walk, attitudes and behavioural beliefs regarding dog walking, and dog and owner demographics. Principal components analysis identified owner profiles regarding attitudes and behavioural beliefs about dog walking. Univariable and multivariable logistic regression were used to identify factors associated with being a regular dog walker (achieving 150mins per week of dog walking) and having a high intention to dog walk (at least 30 mins per day for at least 5 days per week over the next month). RESULTS: Participants walked with their dogs for a median 7 times/week and 230 total minutes/week; regular dog walkers 9 times/week (400 minutes/week), compared to twice/week for irregular dog walkers (45 minutes/week). Being a regular dog walker was positively associated with having a high level of intention to walk the dog in the next month (OR=12.1 95%CI=3.5-42.4, P<0.001), being married or living with a partner (OR=33.5, 95%CI=2.5-458.8, P=0.01), and higher scores on a dog walking habit index (OR=2.1, 95%CI=1.3-3.5, P<0.01). However, higher support from friends for walking was negatively associated with being a regular dog walker (OR=0.3, 95%CI=0.1-0.7, P<0.01). High intention to dog walk was associated with female owners (OR=4.7, 95%CI=1.2-18.5, P=0.03), dogs that lay on the sofa (OR=6.9, 95%CI=1.5-31.8, P=0.01), high levels of self-efficacy to walk the dog over the next month (OR=5.8, 95%CI=1.5-21.9, P=0.01), owner type with an attitude of high responsibility and enjoyment from walking (OR=2.1, 95%CI=1.2-3.8, P=0.02), and higher scores on a dog walking habit index (OR=1.9, 95%CI=1.0-3.7, P=0.05). Reporting someone else walks the dog was negatively associated with high intention (OR=0.1, 95%CI=0.0-0.7, P=0.02). CONCLUSIONS: Interventions to promote dog walking may benefit from increasing intention to dog walk in male owners, forming schedules and routines that involve multiple household members in dog walking, and establishing habits around dog walking. Interventions may also need to address how to overcome barriers and perceived challenges in regards to self-efficacy of dog walking, that may prevent intention from being translated into action.

Functional and recreational dog walking practices in the UK.

Dog walking is a popular everyday activity known to contribute considerably to human health through motivating substantial additional physical activity. However, despite recognition that walking with a dog is substantially different from walking without a dog, little is known sociologically about the practices of dog walking. This study used in-depth interviews with 38 dog owners, combined with autoethnographical observation of dog walking. The aim was to investigate the types of dog walks that occur and the implications of this for the promotion of dog walking to increase human and animal wellbeing. Two distinct types of dog walking were found that had differing influencers and resulting experiences. Functional walks were purposed through feelings of guilt to provide the dog with a convenient form of exercise but were less pleasurable for the owner. In contrast, recreational walks provided significant owner stress-relief and were longer, typically during pleasant weather and at weekends, in less urban environments, and involved more members of the household. Limitations on time availability, conducive weather or accessibility of desirable physical environments for dog walking, generated functional rather than recreational dog walks. These findings have implications for interventions aiming to promote dog walking and for policy relating to the availability of safe and suitable green spaces for encouraging dog walking.

A descriptive epidemiological study of the incidence of newly diagnosed Lyme disease cases in a UK primary care cohort, 1998-2016.

BACKGROUND: Primary care is likely to see the highest number of Lyme disease patients. Despite this, there is limited published data regarding Lyme disease patients accessing primary care in the UK. We aim to describe trends in the incidence of a new diagnosis, and demographics of patients identified in a primary care electronic health database. METHODS: A descriptive epidemiological study of Lyme disease coded patients in UK primary care. 3725 patients coded for Lyme disease during 1998-2016 were identified within The Health Improvement Network (THIN). Incidence rates and the demographics of cases identified were described. Poisson regression was used to analyse socio-demographic characteristics of the cases. RESULTS: There was an increase in annual crude incidence rates, peaking in 2015 at 5.47 (95% CI 4.85-6.14) cases per 100,000 population per year. Multivariable analysis showed there were significant differences in the ages of those affected, incidence of a new diagnosis rose as deprivation levels improved, and that there was a higher incidence of cases living in rural areas compared to urban areas. There was no significant difference between sexes for the UK. Cases were significantly more likely to identify with being white compared to the national population. CONCLUSIONS: An increasing incidence of patients newly coded with Lyme disease related Read codes was identified using data from a UK national primary care database. By comparing these incidence figures with national laboratory-confirmed surveillance data, a multiplication factor of 2.35 (95%CI 1.81-2.88) can be calculated in order to estimate the annual number of cases seen in primary care. The significant socio-demographic variables associated with a Lyme disease diagnosis likely reflect a complex interplay of socio-economic issues, which needs to be further explored. Future work is needed to examine the treatment and management of patients within this database.

Factors associated with daily walking of dogs.

BACKGROUND: Regular physical activity is beneficial to the health of both people and animals. The role of regular exercise undertaken together, such as dog walking, is a public health interest of mutual benefit. Exploration of barriers and incentives to regular dog walking by owners is now required so that effective interventions to promote it can be designed. This study explored a well-characterised cross-sectional dataset of 276 dogs and owners from Cheshire, UK, for evidence of factors associated with the dog being walked once or more per day. RESULTS: Factors independently associated with daily walking included: number of dogs owned (multiple (vs. single) dogs negatively associated); size (medium and possibly large dogs (vs. small) positively associated); and number of people in the household (more people negatively associated). Furthermore, a number of factors related to the dog-owner relationship and the dog's behaviour were associated with daily walking, including: having acquired the dog for a hobby (positively associated); dog lying on furniture (positively associated); dog lying on laps (negatively associated); growling at household members (negatively associated); and playing chase games with the dog (negatively associated). CONCLUSIONS: These findings are consistent with the hypothesis that the strength and nature of the human-dog relationship incentivises dog walking, and that behavioural and demographic factors may affect dog walking via this mechanism. Future studies need to investigate how dog demographic and behavioural factors, plus owner behavioural factors and perceptions of the dog, influence the dog-human relationship in respect to the perceived support and motivation a dog can provide for walking.

How might we increase physical activity through dog walking?: A comprehensive review of dog walking correlates.

BACKGROUND: Physical inactivity and sedentary behaviour are major threats to population health. A considerable proportion of people own dogs, and there is good evidence that dog ownership is associated with higher levels of physical activity. However not all owners walk their dogs regularly. This paper comprehensively reviews the evidence for correlates of dog walking so that effective interventions may be designed to increase the physical activity of dog owners. METHODS: Published findings from 1990-2012 in both the human and veterinary literature were collated and reviewed for evidence of factors associated with objective and self-reported measures of dog walking behaviour, or reported perceptions about dog walking. Study designs included cross-sectional observational, trials and qualitative interviews. RESULTS: There is good evidence that the strength of the dog-owner relationship, through a sense of obligation to walk the dog, and the perceived support and motivation a dog provides for walking, is strongly associated with increased walking. The perceived exercise requirements of the dog may also be a modifiable point for intervention. In addition, access to suitable walking areas with dog supportive features that fulfil dog needs such as off-leash exercise, and that also encourage human social interaction, may be incentivising. CONCLUSION: Current evidence suggests that dog walking may be most effectively encouraged through targeting the dog-owner relationship and by providing dog-supportive physical environments. More research is required to investigate the influence of individual owner and dog factors on 'intention' to walk the dog as well as the influence of human social interaction whilst walking a dog. The effects of policy and cultural practices relating to dog ownership and walking should also be investigated. Future studies must be of a higher quality methodological design, including accounting for the effects of confounding between variables, and longitudinal designs and testing of interventions in a controlled design in order to infer causality.

Could it be colic? Horse-owner decision making and practices in response to equine colic.

BACKGROUND: Little is known about lay understanding and decision making in response to colic. Horse-owners/carers are key to identifying colic and initiating veterinary intervention. Understanding how owners think and act in relation to colic could assist veterinary surgeons in tailoring information about colic with the aim of improving colic outcomes. METHODS: A mixed methods approach was employed including qualitative in-depth interviews and a cross-sectional questionnaire. Qualitative data were analysed using Grounded theory to conceptualise processes involved in horse-owner management of colic. Following this, a cross-sectional survey was designed to test these concepts. Cluster analysis explored the role of the human-horse relationship upon colic management strategies. RESULTS: Fifteen horse-owners with a range of colic experience participated in the interviews. A theoretical conceptual model was developed and described how horse-owners' recognised, assessed and responded to colic. Three main management strategies were used including 'wait and see', 'lay treatments' and 'seek veterinary assistance'. Actions in response to colic were moderated by owners' experience of colic and interpretation of the severity of colic signs. A postal questionnaire gathered data from 673 horse-owners from the North-West of the UK. The majority (605, 89.9%) of respondents were female. Cluster analysis revealed 5 meaningful groups of horse-owners based upon assessment of questionnaire items on the human-horse relationship. These groups included 2 professional and 3 amateur owner typologies. There were differences in the responses to some questionnaire items among the identified groups. CONCLUSIONS: This study describes lay understanding and management of colic among a population of horse-owners from the North-West of the UK. The information may serve as a basis upon which to tailor existing programmes designed to educate owners about colic management strategies, and may inform veterinarians' interactions with horse-owners.

Owner expectations and surprises of dog ownership experiences in the United Kingdom.

Introduction: Although many owners are satisfied by dog ownership, large numbers of dogs are relinquished annually, with an estimated 130,000 dogs cared for each year by rescue organisations in the UK. Unrealistic ownership expectations are a potential factor in the decision to relinquish and therefore understanding what surprises owners about the realities of ownership and how this meets their expectations is vital. Methods: Using a retrospective cross-sectional cohort study design, as part of Dogs Trust's National Dog Survey 2021, owners were asked 'what has surprised you most about owning a dog?' and to classify how their experiences had compared with their expectations on a list of aspects of ownership as either more than, less than or as expected. Free text responses (n= 2,000) were analysed using reflexive thematic analysis in NVivo Pro (v.12 QSR) and a quantitative summary of classified expectations (n=354,224) was conducted in R. Results: Many aspects of ownership were reported to be as expected, however a discrepancy between expectation and reality regarding some aspects was revealed. The cost of vet visits was greater than expected for the majority of respondents (52%), whilst other factors that often exceeded expectations included buying/rehoming cost (33%) and amount of patience needed (25%). Damage to furniture was less than expected for many (50%) as was damage to garden (33%). From the thematic analysis, four themes were generated that reflected what surprised owners most about ownership: emotional connectedness of human-dog relationships; dog's impact on human health/wellbeing; understanding what dogs are like; and meeting the demands of ownership. Conclusion: Overall these results aid our understanding of dog-human interactions, highlighting the complexity of the dog-owner relationship which may come with unanticipated costs. Whilst this study's results are reassuring given many aspects of ownership were as expected, and surprises were often positive, some areas had greater impacts than expected, raising opportunities for intervention, resources or support. The aim would be to manage owners' expectations prior to acquisition or ensure these are more realistically met, reducing the likelihood of negative welfare implications for both dog and owner.

UK Dog Owners' Pre-Acquisition Information- and Advice-Seeking: A Mixed Methods Study.

Dogs are the most common pet animal species in the UK. Little is known about information and advice gathering within the process of dog acquisition, nor what pre-acquisition research encompasses. This study aimed to better understand the preparatory research undertaken by prospective dog owners in the UK. A 2019 online survey collected quantitative and qualitative data about dog acquisition. Analyses within this study focused on a subset of these current (n = 4381) and potential (n = 2350) owners who had undertaken research, or who reported planning to do so, before acquiring a dog. Additional qualitative data were collected through semi-structured interviews with current (n = 24) and potential (n = 8) dog owners. Among those current owners who had sought information or advice, websites were the most common source of information (76%), followed by family and friends (70%), and online forums (51%). Similar patterns were seen among potential owners. Qualitative data revealed that information was commonly sought on the following: general information about dogs; information about breeds or types of dogs; owner requirements and dog suitability; aspects of dog ownership; and how to source a dog. The majority of prospective owners stated that they had found all the information they wanted (96% of current owners and 90% of potential owners) but some respondents found conflicting advice from different sources and did not know which sources to trust. Our study shows that, for some prospective owners, research into various aspects of dog acquisition and ownership is important. Knowing where to look for correct and unbiased advice, particularly online, is particularly important. Understanding the pre-acquisition research that owners undertake, including the sources they use, information they are interested in finding, and the challenges they face, is of interest to animal welfare and veterinary organisations and those involved in rehoming and selling dogs. This information may help inform interventions aimed at improving the knowledge and decisions made by potential dog owners.

Longevity of companion dog breeds: those at risk from early death.

The companion dog is one of the most phenotypically diverse species. Variability between breeds extends not only to morphology and aspects of behaviour, but also to longevity. Despite this fact, little research has been devoted to assessing variation in life expectancy between breeds or evaluating the potential for phylogenetic characterisation of longevity. Using a dataset of 584,734 unique dogs located within the UK, including 284,734 deceased, we present variation in longevity estimates within the following: parental lineage (purebred = 1 breed, crossbred ≥ 2 breeds), breed (n = 155), body size (large, medium, small), sex (male, female) and cephalic index (brachycephalic, mesocephalic, dolichocephalic). Survival estimates were then partitioned amongst phylogenetic clades: providing evidence that canine evolutionary history (via domestication and associated artificial selection) is associated with breed lifespan. This information provides evidence to inform discussions regarding pedigree health, whilst helping current/prospective owners, breeders, policy makers, funding bodies and welfare organisations improve decision making regarding canine welfare.

Cattle producers' perceptions of biosecurity.

BACKGROUND: The limited use of biosecurity practices by many in the farming community is likely to be due to a range of factors; further understanding of this issue is required. In this study, attitudes and behaviours of producers relating to selected biosecurity practices and the farming industry were studied by interviewing cattle farmers within a 100 km2 study area in north-west England using an interview-based questionnaire. RESULTS: Most producers appeared to be familiar with the broad concept of the term biosecurity, although risks due to indirect contacts, rather than direct (animal) contacts, were more frequently highlighted. Most producers felt the nominated biosecurity practices were in some way useful, however there was not always agreement between the usefulness of a practice and it being undertaken, and vice versa. In agreement with other studies conducted in the UK, farmers most preferred to obtain information and advice on biosecurity from private veterinarians, but also highlighted DEFRA as a source. CONCLUSIONS: This study highlights the importance of understanding the motivators and barriers behind the uptake of biosecurity practices on farms, as perceptions are variable. Further understanding of these issues is needed in order to more effectively communicate information in regards to herd health and disease prevention. By identifying differences in producers' attitudes, programs can be tailored specifically to individuals' needs.

Prevalence and molecular characterisation of Eimeria species in Ethiopian village chickens.

BACKGROUND: Coccidiosis, caused by species of the apicomplexan parasite Eimeria, is a major disease of chickens. Eimeria species are present world-wide, and are ubiquitous under intensive farming methods. However, prevalence of Eimeria species is not uniform across production systems. In developing countries such as Ethiopia, a high proportion of chicken production occurs on rural smallholdings (i.e. 'village chicken production') where infectious diseases constrain productivity and surveillance is low. Coccidiosis is reported to be prevalent in these areas. However, a reliance on oocyst morphology to determine the infecting species may impede accurate diagnosis. Here, we used cross-sectional and longitudinal studies to investigate the prevalence of Eimeria oocyst shedding at two rural sites in the Ethiopian highlands. RESULTS: Faecal samples were collected from 767 randomly selected chickens in May or October 2011. In addition, 110 chickens were sampled in both May and October. Eimeria oocysts were detected microscopically in 427 (56%, 95% confidence interval (95% CI) 52-59%) of the 767 faecal samples tested. Moderate clustering of positive birds was detected within households, perhaps suggesting common risk factors or exposure pathways. Seven species of Eimeria were detected by real time PCR in a subset of samples further analysed, with the prevalence of some species varying by region. Co-infections were common; 64% (23/36, 95% CI 46-79%) of positive samples contained more than one Eimeria spp. Despite frequent infection and co-infection overt clinical disease was not reported. Eimeria oocysts were detected significantly more frequently in October (248/384, 65%, 95% CI 60-69%), following the main rainy season, compared to May (179/383, 47%, 95% CI 42-52%, p < 0.001). Eimeria oocyst positivity in May did not significantly affect the likelihood of detecting Eimeria oocyst five months later perhaps suggesting infection with different species or immunologically distinct strains. CONCLUSIONS: Eimeria spp oocysts may be frequently detected in faecal samples from village chickens in Ethiopia. Co-infection with multiple Eimeria spp was common and almost half of Eimeria positive birds had at least one highly pathogenic species detected. Despite this, all sampled birds were free of overt disease. Although there was no evidence of a difference in the prevalence of oocysts in faecal samples between study regions, there was evidence of variation in the prevalence of some species, perhaps suggesting regional differences in exposure to risk factors associated with the birds, their management and/or location-specific environmental and ecological factors.

Pooches on a platform: Text mining twitter for sector perceptions of dogs during a global pandemic.

Introduction: Businesses commonly text mine Twitter data to identify patterns and extract valuable information. However, this method is rarely applied to the animal welfare sector. Here, we describe Twitter conversations regarding dogs during a global pandemic, assess the evolution of sentiment, and examine the dynamics of sector influence. Methods: Between March and August 2020, we gathered 61,088 unique tweets from the United Kingdom and Republic of Ireland, relating to COVID-19 and dogs. Tweets were assigned to one of four pandemic phases and active accounts were assigned to a sector: Personal (i.e., UK and ROI public), Press (i.e., mass media), State (i.e., Government, Police, and NHS), and Other (i.e., welfare organizations, social enterprises, research organizations, charity, and business). Results: Word frequency and sentiment analysis between phases and sectors were assessed, and cross correlation functions and lagged regressions were used to evaluate sector influence. Topical foci of conversations included: meat trade, separation anxiety and dog theft. Sentiment score remained stable until the last phase where sentiment decreased (F 3, 78, 508 = 44.4, p < 0.001), representing an increased use of negative language. Sentiment differed between the four sectors (F 3, 11, 794 = 52.2, p < 0.001), with Personal and Press accounts presenting the greatest use of negative language. Personal accounts were initially partly influenced by State accounts (R = -0.26; p = 0.05), however this altered to Press accounts by the last phase (R = -0.31; p = 0.02). Discussion: Our findings highlight that whilst Personal accounts may affect sector-specific messaging online, perhaps more importantly: language used, and sentiment expressed by Press, State and Other accounts may influence public perception. This draws attention to the importance of sector responsibility regarding accurate and appropriate messaging, as irresponsible/ill-considered comments or campaigns may impact future human-animal interaction.

"Do Your Homework as Your Heart Takes over When You Go Looking": Factors Associated with Pre-Acquisition Information-Seeking among Prospective UK Dog Owners.

The factors influencing why and how people decide to acquire a dog are not well understood and little is known about the extent to which prospective owners undertake preparatory research. This study aimed to better understand what factors influence whether prospective dog owners in the UK conduct preparatory research. A 2019 online survey of current (n = 8050) and potential (n = 2884) dog owners collected quantitative and qualitative data. Additional qualitative data were collected through semi-structured interviews with current (n = 166) and potential (n = 10) dog owners. Of the current owners surveyed, 54% stated that they had looked for advice or information prior to acquiring their dog. Of potential owners, 68% reported already having looked for information, while a further 14% were planning to undertake research prior to acquiring a dog. Those with previous dog ownership experience were less likely to undertake pre-acquisition research, as were those who had worked with dogs. Demographic factors were also associated with the likelihood of conducting pre-acquisition research, with younger prospective owners being more likely to have undertaken research, as well as those with formal education qualifications. Among current owners, pre-acquisition research was more likely among those who acquired their dog through a breeder; a specific breed or a mix of two breeds; or as a puppy. Qualitative data were consistent with and added additional understanding and context to these findings. Almost half of current owners did not conduct pre-acquisition research, highlighting the need for increased awareness of its importance and the development of targeted interventions to encourage this activity. Understanding the different factors that influence whether dog owners undertake research may be of interest to animal welfare and veterinary organisations, in order to inform interventions to better prepare people for dog acquisition.

National Dog Survey: Describing UK Dog and Ownership Demographics.

With dogs being the most commonly owned companion animal in the United Kingdom, knowledge about dog demographics is important in understanding the impact of dogs on society. Furthermore, understanding the demography of dog owners is also important to better target support to dogs and their owners to achieve optimal welfare in the canine population. Combining natural fluctuations in the population and unprecedented events such as the COVID-19 pandemic, the need for an up-to-date large-scale dataset is even more paramount. In order to address this, Dogs Trust launched the 'National Dog Survey' to provide a large population-level dataset that will help identify key areas of concern and needs of owners and their dogs. The online survey was completed by a total of 354,046 respondents owning dogs in the UK, providing data for 440,423 dogs. The results of this study highlight dog demographics, including acquisition and veterinary factors, as well as owner demographic and household information. Finally, general trends in ownership, and more specifically those following the COVID-19 pandemic, are described. This paper's findings provide valuable insight into the current population of dogs and their owners in the UK, allowing for the most appropriate products, services, interventions and regulations to be developed, reducing the likelihood of negative welfare outcomes such as health and behaviour issues, relinquishment or euthanasia. Furthermore, with significant changes to the dog population following the COVID-19 pandemic highlighted, this dataset serves as an up-to-date baseline for future study comparisons to continue to monitor trends and patterns of the dog population and dog owners going forwards.

Why Do People Want Dogs? A Mixed-Methods Study of Motivations for Dog Acquisition in the United Kingdom.

With an estimated 12. 5 million dogs in the UK alone, many people acquire a dog at some point during their lives. However, there are gaps in understanding about why UK owners decide to get dogs. Using a mixed-methods convergent design, this study identified the reasoning behind dog acquisition in a sample of UK current and prospective owners. An online survey of current (n = 8,050) and potential (n = 2,884) dog owners collected quantitative and qualitative data. Current owners were asked about the acquisition of their most recently acquired dog, whilst potential owners were asked about their dog ownership aspirations. Additional qualitative data were collected through semi-structured interviews with current (n = 166) and potential (n = 10) dog owners. Interviews focused on the factors that affected why and how people acquire dogs. Of survey responses, companionship for the respondent was the most common reason for wanting to get a dog, reported by 79.4 and 87.8% of current and potential owners, respectively. Facilitating exercise was reported as a reason for wanting to get a dog by 48.2 and 69.7% of current and potential owners, respectively. There were significant differences between current and potential owners in their likelihood of reporting pre-defined reasons, factors and influences involved in their decision to get a dog. Compared to current owners, potential owners were significantly more likely to report being motivated by most of the survey response options offered (including companionship for themselves or other adults in the household, helping a dog in need, lifestyle changes and previous experiences of meeting dogs), suggesting that current ownership status may affect experience and/or reporting expectations around dog ownership. Reflexive thematic analysis of qualitative data confirmed the importance of these motivations and identified additional reasons and factors that drive dog acquisition. These were organized into three overarching themes: Self-Related Motivation, Social-Based Motivation, and Dog-Related Positive Affect-Based Motivation. These findings provide insights into owners' expectations of ownership which may inform the development of interventions to support potential owners' decision-making around acquisition to maximize both dog and human welfare.

Impact of Changes in Time Left Alone on Separation-Related Behaviour in UK Pet Dogs.

Separation-related behaviours (SRBs), including but not limited to vocalisation, pacing, destruction and toileting, occur in the absence of human company. As well as being problematic for the dogs' owners, such behaviours indicate that the dogs' emotional state is compromised. As part of the COVID-19 pandemic, time spent alone decreased considerably for many pet dogs, leading to concerns about the development of SRBs when dogs are left alone more again. The main aim of this study was to test the hypothesis that dogs whose time left alone decreased most (compared to a February 2020 pre-COVID baseline) would be at greatest risk of developing new signs of SRB when time left alone increased again. To achieve this aim, we utilised survey data gathered from dog owners between 4th May and 3rd July 2020, during the first COVID-19 'lockdown' period in the United Kingdom (UK), and a follow-up survey of the same dog-owner cohort, completed when restrictions had eased between 10th October and 2nd November 2020. Individual dogs fluctuated considerably in whether they showed signs of SRB or not across the study period (n = 1807). Overall, the prevalence of SRB in the population decreased from 22.1% to 17.2%, as did the time dogs were left alone for between February and October 2020. However, 9.9% of dogs had developed new signs of SRB by the follow-up survey in October 2020, with dogs whose leaving hours decreased most during lockdown restrictions being at increased risk of developing SRBs. These findings have implications for our understanding of the etiology of SRB, by showing a link between changes in owner routine and SRB risk.

Estimating the potential for global dissemination of pandemic pathogens using the global airline network and healthcare development indices.

Pandemics have the potential to incur significant health and economic impacts, and can reach a large number of countries from their origin within weeks. Early identification and containment of a newly emerged pandemic within the source country is key for minimising global impact. To identify a country's potential to control and contain a pathogen with pandemic potential, we compared the quality of a country's healthcare system against its global airline connectivity. Healthcare development was determined using three multi-factorial indices, while detailed airline passenger data was used to identify the global connectivity of all countries. Proximities of countries to a putative 'Worst Case Scenario' (extreme high-connectivity and low-healthcare development) were calculated. We found a positive relationship between a country's connectivity and healthcare metrics. We also identified countries that potentially pose the greatest risk for pandemic dissemination, notably Dominican Republic, India and Pakistan. China and Mexico, both sources of recent influenza and coronavirus pandemics were also identified as among the highest risk countries. Collectively, lower-middle and upper-middle income countries represented the greatest risk, while high income countries represented the lowest risk. Our analysis represents an alternative approach to identify countries where increased within-country disease surveillance and pandemic preparedness may benefit global health.

Accessing veterinary healthcare during the COVID-19 pandemic: A mixed-methods analysis of UK and Republic of Ireland dog owners' concerns and experiences.

BACKGROUND: This study explored dog owners' concerns and experiences related to accessing veterinary healthcare during the COVID-19 pandemic. METHODS: Data were obtained through two cross-sectional owner-completed surveys conducted in May (first nationwide lockdown) and October 2020 and owner-completed diaries (April-November 2020). Diaries and relevant open-ended survey questions were analysed qualitatively to identify themes. Survey responses concerning veterinary healthcare access were summarised and compared using chi-square tests. RESULTS: During the initial months of the pandemic, veterinary healthcare availability worried 32.4% (n = 1431/4922) of respondents. However, between 23 March and 4 November 2020, 99.5% (n = 1794/1843) of those needing to contact a veterinarian managed to do so. Delays/cancellations of procedures affected 28.0% (n = 82/293) of dogs that owners planned to neuter and 34.2% (n = 460/1346) of dogs that owners intended to vaccinate. Qualitative themes included COVID-19 safety precautions, availability of veterinary healthcare and the veterinarian-client relationship. CONCLUSION: Veterinary healthcare availability concerned many owners during the COVID-19 pandemic. Access to veterinary healthcare for emergencies remained largely available, but prophylactic treatments were delayed for some dogs.

A randomized triple blind trial to assess the effect of an anthelmintic programme for working equids in Morocco.

BACKGROUND: Gastro-intestinal parasitism has been identified as a significant cause of disease in working equids in many countries. This randomized triple-blind trial was designed to assess the impact of an anthelmintic treatment programme (using oral ivermectin and fenbendazole) comparing treated and placebo control populations of working donkeys, mules and horses in field conditions in Morocco. In particular, we assessed animal body weight and condition score, together with a questionnaire-based owner evaluation of number of subjective animal health parameters. Faecal worm egg count was also measured. RESULTS: 239 animals completed the full study, 130 in the treatment group and 109 in the control group. Although the average animal weight increased during the study, this change was not significantly different between the two groups. Animals in the treatment group had a significantly lower strongyle worm egg count and increased in body condition score compared to animals in the control group at each examination during the study period. Owners of animals in the treatment group reported improvement in health and work ability and a beneficial effect on pruritus during the early period of the study. These differences in owner perception between treatment groups had disappeared in the latter stages of the study. CONCLUSION: This study demonstrated that a routine anthelmintic treatment programme of three treatments annually can have a significant effect on faecal worm egg count. There may be beneficial consequences for the animal health and productivity. Further research on other populations of working equids in different environments would facilitate the objective planning of effective parasite control strategies for specific situations and provide better understanding of the likely clinical benefits of such programmes.