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1.

Contrast coding in the electrosensory system: parallels with visual computation.

Clarke, Stephen E; Longtin, André; Maler, Leonard.

Nat Rev Neurosci; 16(12): 733-44, 2015 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-26558527

2.

Balanced ionotropic receptor dynamics support signal estimation via voltage-dependent membrane noise.

Marcoux, Curtis M; Clarke, Stephen E; Nesse, William H; Longtin, Andre; Maler, Leonard.

J Neurophysiol; 115(1): 530-45, 2016 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-26561607

3.

Speed-invariant encoding of looming object distance requires power law spike rate adaptation.

Clarke, Stephen E; Naud, Richard; Longtin, André; Maler, Leonard.

Proc Natl Acad Sci U S A; 110(33): 13624-9, 2013 Aug 13.

Artículo en Inglés | MEDLINE | ID: mdl-23898185

4.

A neural code for looming and receding motion is distributed over a population of electrosensory ON and OFF contrast cells.

Clarke, Stephen E; Longtin, André; Maler, Leonard.

J Neurosci; 34(16): 5583-94, 2014 Apr 16.

Artículo en Inglés | MEDLINE | ID: mdl-24741048

5.

Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.

Sakatis, Melanie Z; Reese, Melinda J; Harrell, Andrew W; Taylor, Maxine A; Baines, Ian A; Chen, Liangfu; Bloomer, Jackie C; Yang, Eric Y; Ellens, Harma M; Ambroso, Jeffrey L; Lovatt, Cerys A; Ayrton, Andrew D; Clarke, Stephen E.

Chem Res Toxicol; 25(10): 2067-82, 2012 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-22931300

6.

Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation.

Callan, Hayley E; Jenkins, Rosalind E; Maggs, James L; Lavergne, Sidonie N; Clarke, Stephen E; Naisbitt, Dean J; Park, B Kevin.

Chem Res Toxicol; 22(5): 937-48, 2009 May.

Artículo en Inglés | MEDLINE | ID: mdl-19358516

7.

Cellular and Network Mechanisms May Generate Sparse Coding of Sequential Object Encounters in Hippocampal-Like Circuits.

Trinh, Anh-Tuan; Clarke, Stephen E; Harvey-Girard, Erik; Maler, Leonard.

eNeuro; 6(4)2019.

Artículo en Inglés | MEDLINE | ID: mdl-31324676

8.

Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.

Sanderson, Joseph P; Hollis, Frank J; Maggs, James L; Clarke, Stephen E; Naisbitt, Dean J; Park, B Kevin.

Drug Metab Dispos; 36(12): 2424-8, 2008 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-18765684

9.

Analog Signaling With the "Digital" Molecular Switch CaMKII.

Clarke, Stephen E.

Front Comput Neurosci; 12: 92, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30524260

10.

Investigation of the immunogenicity of diclofenac and diclofenac metabolites.

Naisbitt, Dean J; Sanderson, Louise S; Meng, Xiaoli; Stachulski, Andrew V; Clarke, Stephen E; Park, B Kevin.

Toxicol Lett; 168(1): 45-50, 2007 Jan 10.

Artículo en Inglés | MEDLINE | ID: mdl-17123753

11.

Feedback Synthesizes Neural Codes for Motion.

Clarke, Stephen E; Maler, Leonard.

Curr Biol; 27(9): 1356-1361, 2017 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-28457872

12.

The neural dynamics of sensory focus.

Clarke, Stephen E; Longtin, André; Maler, Leonard.

Nat Commun; 6: 8764, 2015 Nov 09.

Artículo en Inglés | MEDLINE | ID: mdl-26549346

13.

Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation.

Naisbitt, Dean J; Yang, Emma L; Alhaidari, Mohammad; Berry, Neil G; Lawrenson, Alexandre S; Farrell, John; Martin, Philip; Strebel, Klaus; Owen, Andrew; Pye, Matthew; French, Neil S; Clarke, Stephen E; O'Neill, Paul M; Park, B Kevin.

AIDS; 29(18): 2385-95, 2015 Nov 28.

Artículo en Inglés | MEDLINE | ID: mdl-26372480

14.

Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.

Kenny, Jane R; Maggs, James L; Meng, Xiaoli; Sinnott, Deborah; Clarke, Stephen E; Park, B Kevin; Stachulski, Andrew V.

J Med Chem; 47(11): 2816-25, 2004 May 20.

Artículo en Inglés | MEDLINE | ID: mdl-15139759

15.

Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.

Sanderson, Joseph P; Naisbitt, Dean J; Farrell, John; Ashby, Charlotte A; Tucker, M Jane; Rieder, Michael J; Pirmohamed, Munir; Clarke, Stephen E; Park, B Kevin.

J Immunol; 178(9): 5533-42, 2007 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-17442935

16.

Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan).

Baldwin, Sandra J; Bramhall, Jo L; Ashby, Charlotte A; Yue, Lin; Murdock, Paul R; Hood, Steven R; Ayrton, Andrew D; Clarke, Stephen E.

Drug Metab Dispos; 34(6): 1063-9, 2006 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-16531474

17.

Activation of T cells by carbamazepine and carbamazepine metabolites.

Wu, Ying; Sanderson, Joseph P; Farrell, John; Drummond, Nicola S; Hanson, Anita; Bowkett, Elizabeth; Berry, Neil; Stachulski, Andrew V; Clarke, Stephen E; Pichler, Werner J; Pirmohamed, Munir; Park, B Kevin; Naisbitt, Dean J.

J Allergy Clin Immunol; 118(1): 233-41, 2006 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-16815161

18.

Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity.

Kenny, Jane R; Maggs, James L; Tettey, Justice N A; Harrell, Andrew W; Parker, Steven G; Clarke, Stephen E; Park, B Kevin.

Drug Metab Dispos; 33(2): 271-81, 2005 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-15523047

19.

Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine.

Galetin, Aleksandra; Clarke, Stephen E; Houston, J Brian.

Drug Metab Dispos; 31(9): 1108-16, 2003 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-12920166

20.

Quinidine and haloperidol as modifiers of CYP3A4 activity: multisite kinetic model approach.

Galetin, Aleksandra; Clarke, Stephen E; Houston, J Brian.

Drug Metab Dispos; 30(12): 1512-22, 2002 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-12433827

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Contrast coding in the electrosensory system: parallels with visual computation.

Balanced ionotropic receptor dynamics support signal estimation via voltage-dependent membrane noise.

Speed-invariant encoding of looming object distance requires power law spike rate adaptation.

A neural code for looming and receding motion is distributed over a population of electrosensory ON and OFF contrast cells.

Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.

Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation.

Cellular and Network Mechanisms May Generate Sparse Coding of Sequential Object Encounters in Hippocampal-Like Circuits.

Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.

Analog Signaling With the "Digital" Molecular Switch CaMKII.

Investigation of the immunogenicity of diclofenac and diclofenac metabolites.

Feedback Synthesizes Neural Codes for Motion.

The neural dynamics of sensory focus.

Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation.

Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.

Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.

Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan).

Activation of T cells by carbamazepine and carbamazepine metabolites.

Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity.

Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine.

Quinidine and haloperidol as modifiers of CYP3A4 activity: multisite kinetic model approach.