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1.

VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

English, Justin G; Olsen, Reid H J; Lansu, Katherine; Patel, Michael; White, Karoline; Cockrell, Adam S; Singh, Darshan; Strachan, Ryan T; Wacker, Daniel; Roth, Bryan L.

Cell; 178(3): 748-761.e17, 2019 07 25.

Artículo en Inglés | MEDLINE | ID: mdl-31280962

2.

VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

English, Justin G; Olsen, Reid H J; Lansu, Katherine; Patel, Michael; White, Karoline; Cockrell, Adam S; Singh, Darshan; Strachan, Ryan T; Wacker, Daniel; Roth, Bryan L.

Cell; 178(4): 1030, 2019 Aug 08.

Artículo en Inglés | MEDLINE | ID: mdl-31398329

3.

Hypergraph models of biological networks to identify genes critical to pathogenic viral response.

Feng, Song; Heath, Emily; Jefferson, Brett; Joslyn, Cliff; Kvinge, Henry; Mitchell, Hugh D; Praggastis, Brenda; Eisfeld, Amie J; Sims, Amy C; Thackray, Larissa B; Fan, Shufang; Walters, Kevin B; Halfmann, Peter J; Westhoff-Smith, Danielle; Tan, Qing; Menachery, Vineet D; Sheahan, Timothy P; Cockrell, Adam S; Kocher, Jacob F; Stratton, Kelly G; Heller, Natalie C; Bramer, Lisa M; Diamond, Michael S; Baric, Ralph S; Waters, Katrina M; Kawaoka, Yoshihiro; McDermott, Jason E; Purvine, Emilie.

BMC Bioinformatics; 22(1): 287, 2021 May 29.

Artículo en Inglés | MEDLINE | ID: mdl-34051754

4.

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice.

Cockrell, Adam S; Leist, Sarah R; Douglas, Madeline G; Baric, Ralph S.

Mamm Genome; 29(7-8): 367-383, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-30043100

5.

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Peck, Kayla M; Cockrell, Adam S; Yount, Boyd L; Scobey, Trevor; Baric, Ralph S; Heise, Mark T.

J Virol; 89(8): 4696-9, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25653445

6.

Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection.

Cockrell, Adam S; Peck, Kayla M; Yount, Boyd L; Agnihothram, Sudhakar S; Scobey, Trevor; Curnes, Nicole R; Baric, Ralph S; Heise, Mark T.

J Virol; 88(9): 5195-9, 2014 May.

Artículo en Inglés | MEDLINE | ID: mdl-24574399

7.

A compendium of multi-omics data illuminating host responses to lethal human virus infections.

Eisfeld, Amie J; Anderson, Lindsey N; Fan, Shufang; Walters, Kevin B; Halfmann, Peter J; Westhoff Smith, Danielle; Thackray, Larissa B; Tan, Qing; Sims, Amy C; Menachery, Vineet D; Schäfer, Alexandra; Sheahan, Timothy P; Cockrell, Adam S; Stratton, Kelly G; Webb-Robertson, Bobbie-Jo M; Kyle, Jennifer E; Burnum-Johnson, Kristin E; Kim, Young-Mo; Nicora, Carrie D; Peralta, Zuleyma; N'jai, Alhaji U; Sahr, Foday; van Bakel, Harm; Diamond, Michael S; Baric, Ralph S; Metz, Thomas O; Smith, Richard D; Kawaoka, Yoshihiro; Waters, Katrina M.

Sci Data; 11(1): 328, 2024 Apr 02.

Artículo en Inglés | MEDLINE | ID: mdl-38565538

8.

A randomized, controlled, feasibility study of RD-X19 in subjects with mild-to-moderate COVID-19 in the outpatient setting.

Stasko, Nathan; Cockrell, Adam S; Kocher, Jacob F; Henson, Ibrahim; Emerson, David; Wang, Ye; Smith, Jonathan R; Henderson, Nathan H; Wood, Hillary; Bradrick, Shelton S; Jones, Terry; Santander, Jorge; McNeil, John G.

Clin Transl Sci; 15(5): 1291-1303, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35137532

9.

Visible blue light inactivates SARS-CoV-2 variants and inhibits Delta replication in differentiated human airway epithelia.

Kocher, Jacob; Arwood, Leslee; Roberts, Rachel C; Henson, Ibrahim; Annas, Abigail; Emerson, David; Stasko, Nathan; Fulcher, M Leslie; Brotton, Marisa; Randell, Scott H; Cockrell, Adam S.

bioRxiv; 2022 Jan 31.

Artículo en Inglés | MEDLINE | ID: mdl-35132416

10.

The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles.

Cockrell, Adam S; van Praag, Henriette; Santistevan, Nicholas; Ma, Hong; Kafri, Tal.

Retrovirology; 8: 51, 2011 Jun 24.

Artículo en Inglés | MEDLINE | ID: mdl-21702950

11.

Visible blue light inhibits infection and replication of SARS-CoV-2 at doses that are well-tolerated by human respiratory tissue.

Stasko, Nathan; Kocher, Jacob F; Annas, Abigail; Henson, Ibrahim; Seitz, Theresa S; Miller, Joy M; Arwood, Leslee; Roberts, Rachel C; Womble, Thomas M; Keller, Emily G; Emerson, Soren; Bergmann, Michael; Sheesley, Ashley N Y; Strong, Rebecca J; Hurst, Brett L; Emerson, David; Tarbet, E Bart; Bradrick, Shelton S; Cockrell, Adam S.

Sci Rep; 11(1): 20595, 2021 10 18.

Artículo en Inglés | MEDLINE | ID: mdl-34663881

12.

Genetically Engineering a Susceptible Mouse Model for MERS-CoV-Induced Acute Respiratory Distress Syndrome.

Leist, Sarah R; Cockrell, Adam S.

Methods Mol Biol; 2099: 137-159, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-31883094

13.

Precision mouse models with expanded tropism for human pathogens.

Wahl, Angela; De, Chandrav; Abad Fernandez, Maria; Lenarcic, Erik M; Xu, Yinyan; Cockrell, Adam S; Cleary, Rachel A; Johnson, Claire E; Schramm, Nathaniel J; Rank, Laura M; Newsome, Isabel G; Vincent, Heather A; Sanders, Wes; Aguilera-Sandoval, Christian R; Boone, Allison; Hildebrand, William H; Dayton, Paul A; Baric, Ralph S; Pickles, Raymond J; Braunstein, Miriam; Moorman, Nathaniel J; Goonetilleke, Nilu; Victor Garcia, J.

Nat Biotechnol; 37(10): 1163-1173, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31451733

14.

Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease.

Douglas, Madeline G; Kocher, Jacob F; Scobey, Trevor; Baric, Ralph S; Cockrell, Adam S.

Virology; 517: 98-107, 2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29277291

15.

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques.

Cockrell, Adam S; Johnson, Joshua C; Moore, Ian N; Liu, David X; Bock, Kevin W; Douglas, Madeline G; Graham, Rachel L; Solomon, Jeffrey; Torzewski, Lisa; Bartos, Christopher; Hart, Randy; Baric, Ralph S; Johnson, Reed F.

Sci Rep; 8(1): 10727, 2018 Jul 16.

Artículo en Inglés | MEDLINE | ID: mdl-30013082

16.

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

Maurizio, Paul L; Ferris, Martin T; Keele, Gregory R; Miller, Darla R; Shaw, Ginger D; Whitmore, Alan C; West, Ande; Morrison, Clayton R; Noll, Kelsey E; Plante, Kenneth S; Cockrell, Adam S; Threadgill, David W; Pardo-Manuel de Villena, Fernando; Baric, Ralph S; Heise, Mark T; Valdar, William.

G3 (Bethesda); 8(2): 427-445, 2018 02 02.

Artículo en Inglés | MEDLINE | ID: mdl-29187420

17.

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis.

Chefer, Svetlana; Seidel, Jurgen; Cockrell, Adam S; Yount, Boyd; Solomon, Jeffrey; Hagen, Katie R; Liu, David X; Huzella, Louis M; Kumar, Mia R; Postnikova, Elena; Bohannon, J Kyle; Lackemeyer, Matthew G; Cooper, Kurt; Endlich-Frazier, Ariel; Sharma, Heema; Thomasson, David; Bartos, Christopher; Sayre, Philip J; Sims, Amy; Dyall, Julie; Holbrook, Michael R; Jahrling, Peter B; Baric, Ralph S; Johnson, Reed F.

mSphere; 3(6)2018 12 12.

Artículo en Inglés | MEDLINE | ID: mdl-30541777

18.

Gene delivery by lentivirus vectors.

Cockrell, Adam S; Kafri, Tal.

Mol Biotechnol; 36(3): 184-204, 2007 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-17873406

19.

Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses.

Cockrell, Adam S; Beall, Anne; Yount, Boyd; Baric, Ralph.

Methods Mol Biol; 1602: 59-81, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28508214

20.

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.

Menachery, Vineet D; Gralinski, Lisa E; Mitchell, Hugh D; Dinnon, Kenneth H; Leist, Sarah R; Yount, Boyd L; Graham, Rachel L; McAnarney, Eileen T; Stratton, Kelly G; Cockrell, Adam S; Debbink, Kari; Sims, Amy C; Waters, Katrina M; Baric, Ralph S.

mSphere; 2(6)2017.

Artículo en Inglés | MEDLINE | ID: mdl-29152578

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VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

Hypergraph models of biological networks to identify genes critical to pathogenic viral response.

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice.

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection.

A compendium of multi-omics data illuminating host responses to lethal human virus infections.

A randomized, controlled, feasibility study of RD-X19 in subjects with mild-to-moderate COVID-19 in the outpatient setting.

Visible blue light inactivates SARS-CoV-2 variants and inhibits Delta replication in differentiated human airway epithelia.

The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles.

Visible blue light inhibits infection and replication of SARS-CoV-2 at doses that are well-tolerated by human respiratory tissue.

Genetically Engineering a Susceptible Mouse Model for MERS-CoV-Induced Acute Respiratory Distress Syndrome.

Precision mouse models with expanded tropism for human pathogens.

Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease.

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques.

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis.

Gene delivery by lentivirus vectors.

Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses.

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.