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1.

Perinatal thymic-derived CD8αß-expressing Î³Î´ T cells are innate IFN-Î³ producers that expand in IL-7R-STAT5B-driven neoplasms.

Sumaria, Nital; Fiala, Gina J; Inácio, Daniel; Curado-Avelar, Marta; Cachucho, Ana; Pinheiro, Rúben; Wiesheu, Robert; Kimura, Shunsuke; Courtois, Lucien; Blankenhaus, Birte; Darrigues, Julie; Suske, Tobias; Almeida, Afonso R M; Minguet, Susana; Asnafi, Vahid; Lhermitte, Ludovic; Mullighan, Charles G; Coffelt, Seth B; Moriggl, Richard; Barata, João T; Pennington, Daniel J; Silva-Santos, Bruno.

Nat Immunol; 2024 May 27.

Artículo en Inglés | MEDLINE | ID: mdl-38802512

2.

Stressed out neutrophils drive metastasis.

Lupo, Federico; Coffelt, Seth B.

Immunity; 57(4): 840-842, 2024 Apr 09.

Artículo en Inglés | MEDLINE | ID: mdl-38599176

3.

IL-27 maintains cytotoxic Ly6C⁺ Î³Î´ T cells that arise from immature precursors.

Wiesheu, Robert; Edwards, Sarah C; Hedley, Ann; Hall, Holly; Tosolini, Marie; Fares da Silva, Marcelo Gregorio Filho; Sumaria, Nital; Castenmiller, Suzanne M; Wardak, Leyma; Optaczy, Yasmin; Lynn, Amy; Hill, David G; Hayes, Alan J; Hay, Jodie; Kilbey, Anna; Shaw, Robin; Whyte, Declan; Walsh, Peter J; Michie, Alison M; Graham, Gerard J; Manoharan, Anand; Halsey, Christina; Blyth, Karen; Wolkers, Monika C; Miller, Crispin; Pennington, Daniel J; Jones, Gareth W; Fournie, Jean-Jacques; Bekiaris, Vasileios; Coffelt, Seth B.

EMBO J; 2024 May 30.

Artículo en Inglés | MEDLINE | ID: mdl-38816652

4.

Revving Up Dendritic Cells while Braking PD-L1 to Jump-Start the Cancer-Immunity Cycle Motor.

Coffelt, Seth B; de Visser, Karin E.

Immunity; 44(4): 722-4, 2016 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-27096314

5.

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.

Wellenstein, Max D; Coffelt, Seth B; Duits, Danique E M; van Miltenburg, Martine H; Slagter, Maarten; de Rink, Iris; Henneman, Linda; Kas, Sjors M; Prekovic, Stefan; Hau, Cheei-Sing; Vrijland, Kim; Drenth, Anne Paulien; de Korte-Grimmerink, Renske; Schut, Eva; van der Heijden, Ingrid; Zwart, Wilbert; Wessels, Lodewyk F A; Schumacher, Ton N; Jonkers, Jos; de Visser, Karin E.

Nature; 572(7770): 538-542, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-31367040

6.

Gut Î³Î´ T cells as guardians, disruptors, and instigators of cancer.

Suzuki, Toshiyasu; Hayman, Liam; Kilbey, Anna; Edwards, Joanne; Coffelt, Seth B.

Immunol Rev; 298(1): 198-217, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32840001

7.

Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model.

Johnson, Síle A; Ormsby, Michael J; Wessel, Hannah M; Hulme, Heather E; Bravo-Blas, Alberto; McIntosh, Anne; Mason, Susan; Coffelt, Seth B; Tait, Stephen W G; Mowat, Allan McI; Milling, Simon W F; Blyth, Karen; Wall, Daniel M.

Eur J Immunol; 51(12): 3228-3238, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34633664

8.

Emerging immunotherapies for metastasis.

Edwards, Sarah C; Hoevenaar, Wilma H M; Coffelt, Seth B.

Br J Cancer; 124(1): 37-48, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33262520

9.

IL-17-producing Î³Î´ T cells and neutrophils conspire to promote breast cancer metastasis.

Coffelt, Seth B; Kersten, Kelly; Doornebal, Chris W; Weiden, Jorieke; Vrijland, Kim; Hau, Cheei-Sing; Verstegen, Niels J M; Ciampricotti, Metamia; Hawinkels, Lukas J A C; Jonkers, Jos; de Visser, Karin E.

Nature; 522(7556): 345-348, 2015 Jun 18.

Artículo en Inglés | MEDLINE | ID: mdl-25822788

10.

LOXL2 in pancreatic tumourigenesis: the complexity of tumour-stromal crosstalk exemplified.

Coffelt, Seth B; Morton, Jennifer P.

Gut; 72(2): 221-222, 2023 02.

Artículo en Inglés | MEDLINE | ID: mdl-35428658

11.

Immune-mediated mechanisms influencing the efficacy of anticancer therapies.

Coffelt, Seth B; de Visser, Karin E.

Trends Immunol; 36(4): 198-216, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25857662

12.

Cancer: Inflammation lights the way to metastasis.

Coffelt, Seth B; de Visser, Karin E.

Nature; 507(7490): 48-9, 2014 Mar 06.

Artículo en Inglés | MEDLINE | ID: mdl-24572360

13.

Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue.

Kumar, Saumya; Basto, Afonso P; Ribeiro, Filipa; Almeida, Silvia C P; Campos, Patricia; Peres, Carina; Pulvirenti, Nadia; Al-Khalidi, Sarwah; Kilbey, Anna; Tosello, Jimena; Piaggio, Eliane; Russo, Momtchilo; Gama-Carvalho, Margarida; Coffelt, Seth B; Roberts, Ed W; Geginat, Jens; Florindo, Helena F; Graca, Luis.

Cell Discov; 10(1): 64, 2024 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-38834551

14.

Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.

Dawson, Amy; Zarou, Martha M; Prasad, Bodhayan; Bittencourt-Silvestre, Joana; Zerbst, Désirée; Himonas, Ekaterini; Hsieh, Ya-Ching; van Loon, Isabel; Blanco, Giovanny Rodriguez; Ianniciello, Angela; Kerekes, Zsombor; Krishnan, Vaidehi; Agarwal, Puneet; Almasoudi, Hassan; McCluskey, Laura; Hopcroft, Lisa E M; Scott, Mary T; Baquero, Pablo; Dunn, Karen; Vetrie, David; Copland, Mhairi; Bhatia, Ravi; Coffelt, Seth B; Tiong, Ong Sin; Wheadon, Helen; Zanivan, Sara; Kirschner, Kristina; Helgason, G Vignir.

Nat Commun; 15(1): 1090, 2024 Feb 05.

Artículo en Inglés | MEDLINE | ID: mdl-38316788

15.

Generation of a novel mouse model for the inducible depletion of macrophages in vivo.

Gheryani, Nabeia; Coffelt, Seth B; Gartland, Alison; Rumney, Robin M H; Kiss-Toth, Endre; Lewis, Claire E; Tozer, Gillian M; Greaves, David R; Dear, T Neil; Miller, Gaynor.

Genesis; 51(1): 41-9, 2013 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-22927121

16.

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

Coffelt, Seth B; Chen, Yung-Yi; Muthana, Munitta; Welford, Abigail F; Tal, Andrea O; Scholz, Alexander; Plate, Karl H; Reiss, Yvonne; Murdoch, Craig; De Palma, Michele; Lewis, Claire E.

J Immunol; 186(7): 4183-90, 2011 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-21368233

17.

Î³Î´ T cells turn the tables on immune-evasive colon cancer.

Coffelt, Seth B; Suzuki, Toshiyasu.

Med; 4(3): 141-142, 2023 03 10.

Artículo en Inglés | MEDLINE | ID: mdl-36905925

18.

PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing Î³Î´ T cells.

Edwards, Sarah C; Hedley, Ann; Hoevenaar, Wilma H M; Wiesheu, Robert; Glauner, Teresa; Kilbey, Anna; Shaw, Robin; Boufea, Katerina; Batada, Nizar; Hatano, Shinya; Yoshikai, Yasunobu; Blyth, Karen; Miller, Crispin; Kirschner, Kristina; Coffelt, Seth B.

J Exp Med; 220(2)2023 02 06.

Artículo en Inglés | MEDLINE | ID: mdl-36480166

19.

Î³Î´ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection.

Quintana, Juan F; Sinton, Matthew C; Chandrasegaran, Praveena; Lestari, Agatha Nabilla; Heslop, Rhiannon; Cheaib, Bachar; Ogunsola, John; Ngoyi, Dieudonne Mumba; Kuispond Swar, Nono-Raymond; Cooper, Anneli; Mabbott, Neil A; Coffelt, Seth B; MacLeod, Annette.

Nat Commun; 14(1): 5279, 2023 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-37644007

20.

ß-Catenin Drives Butyrophilin-like Molecule Loss and Î³Î´ T-cell Exclusion in Colon Cancer.

Suzuki, Toshiyasu; Kilbey, Anna; Casa-Rodríguez, Nuria; Lawlor, Amy; Georgakopoulou, Anastasia; Hayman, Hannah; Yin Swe, Kyi Lai; Nordin, Anna; Cantù, Claudio; Vantourout, Pierre; Ridgway, Rachel A; Byrne, Ryan M; Chen, Lei; Verzi, Michael P; Gay, David M; Gil Vázquez, Ester; Belnoue-Davis, Hayley L; Gilroy, Kathryn; Køstner, Anne Helene; Kersten, Christian; Thuwajit, Chanitra; Andersen, Ditte K; Wiesheu, Robert; Jandke, Anett; Blyth, Karen; Roseweir, Antonia K; Leedham, Simon J; Dunne, Philip D; Edwards, Joanne; Hayday, Adrian; Sansom, Owen J; Coffelt, Seth B.

Cancer Immunol Res; 11(8): 1137-1155, 2023 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-37309673

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Perinatal thymic-derived CD8αß-expressing Î³Î´ T cells are innate IFN-Î³ producers that expand in IL-7R-STAT5B-driven neoplasms.

Stressed out neutrophils drive metastasis.

IL-27 maintains cytotoxic Ly6C⁺ Î³Î´ T cells that arise from immature precursors.

Revving Up Dendritic Cells while Braking PD-L1 to Jump-Start the Cancer-Immunity Cycle Motor.

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.

Gut Î³Î´ T cells as guardians, disruptors, and instigators of cancer.

Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model.

Emerging immunotherapies for metastasis.

IL-17-producing Î³Î´ T cells and neutrophils conspire to promote breast cancer metastasis.

LOXL2 in pancreatic tumourigenesis: the complexity of tumour-stromal crosstalk exemplified.

Immune-mediated mechanisms influencing the efficacy of anticancer therapies.

Cancer: Inflammation lights the way to metastasis.

Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue.

Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.

Generation of a novel mouse model for the inducible depletion of macrophages in vivo.

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

Î³Î´ T cells turn the tables on immune-evasive colon cancer.

PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing Î³Î´ T cells.

Î³Î´ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection.

ß-Catenin Drives Butyrophilin-like Molecule Loss and Î³Î´ T-cell Exclusion in Colon Cancer.