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1.

Sex-Specific Differences in Lipoprotein Production and Clearance.

Conlon, Donna M; Welty, Francine K; Reyes-Soffer, Gissette; Amengual, Jaume.

Arterioscler Thromb Vasc Biol; 43(9): 1617-1625, 2023 09.

Artículo en Inglés | MEDLINE | ID: mdl-37409532

2.

Functional Characterization of Organoids Derived From Irreversibly Damaged Liver of Patients With NASH.

McCarron, Sarah; Bathon, Brooke; Conlon, Donna M; Abbey, Deepti; Rader, Daniel J; Gawronski, Katerina; Brown, Christopher D; Olthoff, Kim M; Shaked, Abraham; Raabe, Tobias D.

Hepatology; 74(4): 1825-1844, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-33901295

3.

Role of sortilin in lipid metabolism.

Conlon, Donna M.

Curr Opin Lipidol; 30(3): 198-204, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30946050

4.

Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy.

Palmer, Elizabeth E; Jarrett, Kelsey E; Sachdev, Rani K; Al Zahrani, Fatema; Hashem, Mais Omar; Ibrahim, Niema; Sampaio, Hugo; Kandula, Tejaswi; Macintosh, Rebecca; Gupta, Rajat; Conlon, Donna M; Billheimer, Jeffrey T; Rader, Daniel J; Funato, Kouichi; Walkey, Christopher J; Lee, Chang Seok; Loo, Christine; Brammah, Susan; Elakis, George; Zhu, Ying; Buckley, Michael; Kirk, Edwin P; Bye, Ann; Alkuraya, Fowzan S; Roscioli, Tony; Lagor, William R.

Hum Mol Genet; 25(14): 3042-3054, 2016 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-27270415

5.

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans.

Cuchel, Marina; Raper, Anna C; Conlon, Donna M; Pryma, Daniel A; Freifelder, Richard H; Poria, Rahul; Cromley, Debra; Li, Xiaoyu; Dunbar, Richard L; French, Benjamin; Qu, Liming; Farver, William; Su, Ching-Chiang; Lund-Katz, Sissel; Baer, Amanda; Ruotolo, Giacomo; Akerblad, Peter; Ryan, Carol S; Xiao, Lan; Kirchgessner, Todd G; Millar, John S; Billheimer, Jeffrey T; Rader, Daniel J.

J Lipid Res; 58(4): 752-762, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28167703

6.

A coding variant in the microsomal triglyceride transfer protein reduces both hepatic steatosis and plasma lipids.

Schneider, Carolin V; Hehl, Leonida; Creasy, Kate T; Vitali, Cecilia; Vell, Mara S; Vujkovic, Marijana; Park, Joseph; Scorletti, Eleonora; Seeling, Katharina S; Rendel, Miriam D; Conlon, Donna M; Huang, Helen; Zandvakili, Inuk; Valmiki, Swati; Schneider, Kai Markus; Hussain, M Mahmood; Rader, Daniel J.

Aliment Pharmacol Ther; 58(2): 238-249, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-37248657

7.

Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions.

Conlon, Donna M; Schneider, Carolin V; Ko, Yi-An; Rodrigues, Amrith; Guo, Kathy; Hand, Nicholas J; Rader, Daniel J.

J Clin Invest; 132(6)2022 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-35113816

8.

Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy.

Caviglia, Jorge Matias; Gayet, Constance; Ota, Tsuguhito; Hernandez-Ono, Antonio; Conlon, Donna M; Jiang, Hongfeng; Fisher, Edward A; Ginsberg, Henry N.

J Lipid Res; 52(9): 1636-51, 2011 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-21719579

9.

TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes.

Quiroz-Figueroa, Katherine; Vitali, Cecilia; Conlon, Donna M; Millar, John S; Tobias, John W; Bauer, Robert C; Hand, Nicholas J; Rader, Daniel J.

J Clin Invest; 131(22)2021 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-34779419

10.

A genome-first approach to mortality and metabolic phenotypes in MTARC1 p.Ala165Thr (rs2642438) heterozygotes and homozygotes.

Schneider, Carolin V; Schneider, Kai Markus; Conlon, Donna M; Park, Joseph; Vujkovic, Marijana; Zandvakili, Inuk; Ko, Yi-An; Trautwein, Christian; Center, Regerneron; Carr, Rotonya M; Strnad, Pavel; Thaiss, Christoph A; Rader, Daniel J.

Med; 2(7): 851-863.e3, 2021 07 09.

Artículo en Inglés | MEDLINE | ID: mdl-34258604

11.

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.

Liu, Ying; Conlon, Donna M; Bi, Xin; Slovik, Katherine J; Shi, Jianting; Edelstein, Hailey I; Millar, John S; Javaheri, Ali; Cuchel, Marina; Pashos, Evanthia E; Iqbal, Jahangir; Hussain, M Mahmood; Hegele, Robert A; Yang, Wenli; Duncan, Stephen A; Rader, Daniel J; Morrisey, Edward E.

Cell Rep; 19(7): 1456-1466, 2017 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-28514664

12.

Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis.

Conlon, Donna M; Thomas, Tiffany; Fedotova, Tatyana; Hernandez-Ono, Antonio; Di Paolo, Gilbert; Chan, Robin B; Ruggles, Kelly; Gibeley, Sarah; Liu, Jing; Ginsberg, Henry N.

J Clin Invest; 126(10): 3852-3867, 2016 10 03.

Artículo en Inglés | MEDLINE | ID: mdl-27599291

13.

Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-Ig(TM)) molecule that specifically and potently neutralizes both IL-1α and IL-1ß.

Lacy, Susan E; Wu, Chengbin; Ambrosi, Dominic J; Hsieh, Chung-Ming; Bose, Sahana; Miller, Renee; Conlon, Donna M; Tarcsa, Edit; Chari, Ravi; Ghayur, Tariq; Kamath, Rajesh V.

MAbs; 7(3): 605-19, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25764208

14.

Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.

Ai, Ding; Baez, Juan M; Jiang, Hongfeng; Conlon, Donna M; Hernandez-Ono, Antonio; Frank-Kamenetsky, Maria; Milstein, Stuart; Fitzgerald, Kevin; Murphy, Andrew J; Woo, Connie W; Strong, Alanna; Ginsberg, Henry N; Tabas, Ira; Rader, Daniel J; Tall, Alan R.

J Clin Invest; 122(5): 1677-87, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22466652

15.

Translocation efficiency of apolipoprotein B is determined by the presence of beta-sheet domains, not pause transfer sequences.

Yamaguchi, Junji; Conlon, Donna M; Liang, John J; Fisher, Edward A; Ginsberg, Henry N.

J Biol Chem; 281(37): 27063-71, 2006 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-16854991

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