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1.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

Skrott, Zdenek; Mistrik, Martin; Andersen, Klaus Kaae; Friis, Søren; Majera, Dusana; Gursky, Jan; Ozdian, Tomas; Bartkova, Jirina; Turi, Zsofia; Moudry, Pavel; Kraus, Marianne; Michalova, Martina; Vaclavkova, Jana; Dzubak, Petr; Vrobel, Ivo; Pouckova, Pavla; Sedlacek, Jindrich; Miklovicova, Andrea; Kutt, Anne; Li, Jing; Mattova, Jana; Driessen, Christoph; Dou, Q Ping; Olsen, Jørgen; Hajduch, Marian; Cvek, Boris; Deshaies, Raymond J; Bartek, Jiri.

Nature; 552(7684): 194-199, 2017 12 14.

Artículo en Inglés | MEDLINE | ID: mdl-29211715

2.

The Promiscuity of Disulfiram in Medicinal Research.

Cvek, Boris.

ACS Med Chem Lett; 14(12): 1610-1614, 2023 Dec 14.

Artículo en Inglés | MEDLINE | ID: mdl-38116411

3.

Multiple deadlocks in the development of nonprofit drugs.

Cvek, Boris.

Drug Discov Today; 27(9): 2411-2414, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35667629

4.

Drug Repurposing for Terminal-Stage Cancer Patients.

Cvek, Boris.

Am J Public Health; 106(6): e3, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-27153031

5.

The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?

Cvek, Boris; Dvorak, Zdenek.

Drug Discov Today; 13(15-16): 716-22, 2008 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-18579431

6.

Antabuse (disulfiram) as a pilot case of nonprofit drug.

Cvek, Boris.

Int J Cancer; 127(10): 2486, 2010 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-20143396

7.

Deubiquitinases (DUBs) and DUB inhibitors: a patent review.

Farshi, Pershang; Deshmukh, Rahul R; Nwankwo, Joseph O; Arkwright, Richard T; Cvek, Boris; Liu, Jinbao; Dou, Q Ping.

Expert Opin Ther Pat; 25(10): 1191-1208, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26077642

8.

Combating endometriosis by blocking proteasome and nuclear factor-kappaB pathways.

Cvek, Boris.

Hum Reprod; 24(11): 2967; author reply 2967-8, 2009 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-19687055

9.

Linking the activity of bortezomib in multiple myeloma and autoimmune diseases.

Skrott, Zdenek; Cvek, Boris.

Crit Rev Oncol Hematol; 92(2): 61-70, 2014 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-24890785

10.

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.

Kast, Richard E; Boockvar, John A; Brüning, Ansgar; Cappello, Francesco; Chang, Wen-Wei; Cvek, Boris; Dou, Q Ping; Duenas-Gonzalez, Alfonso; Efferth, Thomas; Focosi, Daniele; Ghaffari, Seyed H; Karpel-Massler, Georg; Ketola, Kirsi; Khoshnevisan, Alireza; Keizman, Daniel; Magné, Nicolas; Marosi, Christine; McDonald, Kerrie; Muñoz, Miguel; Paranjpe, Ameya; Pourgholami, Mohammad H; Sardi, Iacopo; Sella, Avishay; Srivenugopal, Kalkunte S; Tuccori, Marco; Wang, Weiguang; Wirtz, Christian R; Halatsch, Marc-Eric.

Oncotarget; 4(4): 502-30, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23594434

11.

Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfiram).

Cvek, Boris.

Drug Discov Today; 17(9-10): 409-12, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22192884

12.

Searching for Positive Side Effects of Common Drugs.

Cvek, Boris.

Trends Pharmacol Sci; 38(2): 111, 2017 02.

Artículo en Inglés | MEDLINE | ID: mdl-27823801

13.

Promoting Medical Innovation.

Cvek, Boris.

Health Aff (Millwood); 36(8): 1518, 2017 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-28784748

14.

Proteasome inhibitors.

Cvek, Boris.

Prog Mol Biol Transl Sci; 109: 161-226, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22727422

15.

Diethyldithiocarbamate complex with copper: the mechanism of action in cancer cells.

Skrott, Zdenek; Cvek, Boris.

Mini Rev Med Chem; 12(12): 1184-92, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22931589

16.

The Raffles Dialogue on Human Wellbeing and Security.

Cvek, Boris.

Lancet Glob Health; 4(2): e92, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26823224

17.

The ubiquitin-proteasome system (UPS) and the mechanism of action of bortezomib.

Cvek, Boris; Dvorak, Zdenek.

Curr Pharm Des; 17(15): 1483-99, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-21504411

18.

Low-Income Countries And Repurposed Drugs.

Cvek, Boris.

Health Aff (Millwood); 34(11): 2004, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26526267

19.

Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.

Bachleda, Petr; Vrzal, Radim; Pivnicka, Jakub; Cvek, Boris; Dvorak, Zdenek.

Toxicol Lett; 191(1): 74-8, 2009 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-19686824

20.

Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells.

Cvek, Boris; Milacic, Vesna; Taraba, Jan; Dou, Q Ping.

J Med Chem; 51(20): 6256-8, 2008 Oct 23.

Artículo en Inglés | MEDLINE | ID: mdl-18816109

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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

The Promiscuity of Disulfiram in Medicinal Research.

Multiple deadlocks in the development of nonprofit drugs.

Drug Repurposing for Terminal-Stage Cancer Patients.

The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?

Antabuse (disulfiram) as a pilot case of nonprofit drug.

Deubiquitinases (DUBs) and DUB inhibitors: a patent review.

Combating endometriosis by blocking proteasome and nuclear factor-kappaB pathways.

Linking the activity of bortezomib in multiple myeloma and autoimmune diseases.

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.

Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfiram).

Searching for Positive Side Effects of Common Drugs.

Promoting Medical Innovation.

Proteasome inhibitors.

Diethyldithiocarbamate complex with copper: the mechanism of action in cancer cells.

The Raffles Dialogue on Human Wellbeing and Security.

The ubiquitin-proteasome system (UPS) and the mechanism of action of bortezomib.

Low-Income Countries And Repurposed Drugs.

Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.

Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells.