Detalles de la búsqueda
1.
Cardiotonic steroids on the road to anti-cancer therapy.
Biochim Biophys Acta;
1776(1): 32-57, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17706876
2.
Divergent and regioselective synthesis of 1,2,4- and 1,2,5-trisubstituted imidazoles.
J Org Chem;
73(17): 6816-23, 2008 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-18681408
3.
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
J Med Chem;
50(17): 4122-34, 2007 Aug 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-17658777
4.
The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells.
Mol Cancer Ther;
5(2): 391-9, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16505114
5.
Anti-galectin compounds as potential anti-cancer drugs.
Curr Med Chem;
13(29): 3513-27, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17168720
6.
A lactosylated steroid contributes in vivo therapeutic benefits in experimental models of mouse lymphoma and human glioblastoma.
J Med Chem;
49(5): 1800-7, 2006 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-16509595
7.
Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses.
J Med Chem;
48(3): 849-56, 2005 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-15689169
8.
Are syngeneic mouse tumor models still valuable experimental models in the field of anti-cancer drug discovery?
Int J Oncol;
27(3): 607-16, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16077908
9.
Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.
J Neurosurg;
102(4): 706-14, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15871514
10.
Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases.
J Neuropathol Exp Neurol;
61(7): 585-96, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12125737
11.
3-Aryl-2-quinolone derivatives: synthesis and characterization of in vitro and in vivo antitumor effects with emphasis on a new therapeutical target connected with cell migration.
J Med Chem;
45(12): 2543-55, 2002 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-12036363
12.
Synthesis and in vitro antitumor activity of phenanthrolin-7-one derivatives, analogues of the marine pyridoacridine alkaloids ascididemin and meridine: structure-activity relationship.
J Med Chem;
46(16): 3536-45, 2003 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-12877592
13.
Synthesis and in vitro antitumor activity of novel ring D analogues of the marine pyridoacridine ascididemin: structure-activity relationship.
J Med Chem;
45(17): 3765-71, 2002 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12166949
14.
In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cell migration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton.
Int J Oncol;
21(2): 417-25, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12118340
15.
Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents.
Transl Oncol;
1(1): 1-13, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18607503
16.
UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.
Neoplasia;
10(6): 573-86, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18516294
17.
The Amaryllidaceae isocarbostyril narciclasine induces apoptosis by activation of the death receptor and/or mitochondrial pathways in cancer cells but not in normal fibroblasts.
Neoplasia;
9(9): 766-76, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17898872
18.
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.
Neoplasia;
8(5): 402-12, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16790089
19.
Synthesis and cytotoxic evaluation of analogues of the marine pyridoacridine amphimedine.
Bioorg Med Chem;
10(9): 2845-53, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12110304
20.
Synthesis and in vitro antitumor activity of an isomer of the marine pyridoacridine alkaloid ascididemin and related compounds.
Bioorg Med Chem;
11(20): 4351-6, 2003 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-13129571