RESUMEN
Executive functioning is one of the most researched and debated topics in neuropsychology. Although neuropsychologists routinely consider executive functioning and intelligence in their assessment process, more information is needed regarding the relationship between these constructs. This study reports the results of a canonical correlation study between the most widely used measure of adult intelligence, the Wechsler Adult Intelligence Scale, 3rd edition (WAIS-III; Wechsler, 1997), and the Delis-Kaplan Executive Function System (D-KEFS; Delis, Kaplan, & Kramer, 2001). The results suggest that, despite considerable shared variability, the measures of executive functioning maintain unique variance that is not encapsulated in the construct of global intelligence.
Asunto(s)
Función Ejecutiva , Pruebas de Inteligencia/estadística & datos numéricos , Inteligencia , Escalas de Wechsler/estadística & datos numéricos , Adolescente , Adulto , Femenino , Humanos , MasculinoRESUMEN
Statistical prediction of an outcome variable using multiple independent variables is a common practice in the social and behavioral sciences. For example, neuropsychologists are sometimes called upon to provide predictions of preinjury cognitive functioning for individuals who have suffered a traumatic brain injury. Typically, these predictions are made using standard multiple linear regression models with several demographic variables (e.g., gender, ethnicity, education level) as predictors. Prior research has shown conflicting evidence regarding the ability of such models to provide accurate predictions of outcome variables such as full-scale intelligence (FSIQ) test scores. The present study had two goals: (1) to demonstrate the utility of a set of alternative prediction methods that have been applied extensively in the natural sciences and business but have not been frequently explored in the social sciences and (2) to develop models that can be used to predict premorbid cognitive functioning in preschool children. Predictions of Stanford-Binet 5 FSIQ scores for preschool-aged children is used to compare the performance of a multiple regression model with several of these alternative methods. Results demonstrate that classification and regression trees provided more accurate predictions of FSIQ scores than does the more traditional regression approach. Implications of these results are discussed.
Asunto(s)
Pruebas de Inteligencia , Inteligencia , Modelos Psicológicos , Preescolar , Femenino , Humanos , Masculino , Valor Predictivo de las PruebasRESUMEN
The assessment of sensory-motor functions is a key component of pediatric neuropsychological evaluations following traumatic brain injury (TBI). Sensory-motor processes have recently been shown to be related to larger neural structures and functions, rather than a secondary role played in the past. Recent research has shown sensory-motor functioning serves as a marker for the integrity of the central nervous system. Children's behavior following a TBI has greater variation than seen in adults, which may well relate to greater natural variation and maturational effects. With the recent findings of greater importance of sensory-motor functions, the need for psychometrically sound measures is stressed and various measures are outlined.
Asunto(s)
Lesiones Encefálicas/complicaciones , Lesiones Encefálicas/psicología , Trastornos del Conocimiento/diagnóstico , Pruebas Neuropsicológicas/normas , Desempeño Psicomotor , Niño , Trastornos del Conocimiento/complicaciones , HumanosRESUMEN
Sensory and motor functions are good markers of neurocognitive decline due to their proximity and hierarchical relationship to high-order processes. The current study investigated if patients with Alzheimer's disease (AD) differed from a healthy control group in two tactile perceptual processes: astereognosis and agraphesthesia. Analyses were also conducted to see if these tactile processes were predictive of higher-order cognitive functioning. Twenty-eight patients with AD (mean age = 75.86) were compared to 28 healthy control subjects (mean age = 76.38) and were administered the Dean-Woodcock Sensory Motor Battery and the Woodcock-Johnson Psychoeducational Battery-Revised. Results suggest the patients with AD demonstrated significantly higher levels of tactile disturbance and astereognosis while agraphesthesia was able to predict a substantial portion of the variance in 3/7 cognitive tests and 4/7 cognitive tests, respectively. This included measures of fluid reasoning, visual processing, crystallized language, short-term memory, and auditory processing. These results suggest that astereognosis and agraphesthesia may be good markers of the extent of cognitive impairment in AD and should be included in neuropsychological evaluations due to their functional importance.
Asunto(s)
Agnosia/etiología , Enfermedad de Alzheimer/complicaciones , Trastornos del Conocimiento/etiología , Pruebas Neuropsicológicas , Tacto/fisiología , Anciano , Anciano de 80 o más Años , Femenino , Lateralidad Funcional , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Valor Predictivo de las PruebasRESUMEN
Assessment of patients with depression tends to focus on the psychiatric symptoms of the disorder to quantify distress, potential for suicide, and helps determine the appropriate course of treatment. However, research increasingly reveals comorbid organic and biological deficits in higher order cortical skills and subcortical processes which should be considered when assessing the depressed patient. The current study investigated the presence of cortical and subcortical sensory deficits in a group of 36 patients with Major Depressive Disorder as compared to a group of normal controls. The results of a MANOVA indicated a significant performance difference between depressed and nondepressed participants (Wilks' Lambda = .437, F = 3.68, p > .001). Subsequent univariate tests showed normals performed better on 29 of 35 variables of a sensory-motor battery. Deficits in sensory and motor functioning can have a profound impact on patient functioning and may remit with treatment. Thus, a comprehensive neuropsychological battery for patients with depression should include standardized and psychometrically sound measures of sensory and motor functioning.
Asunto(s)
Encéfalo/fisiopatología , Corteza Cerebral/fisiopatología , Trastorno Depresivo Mayor/fisiopatología , Actividad Motora/fisiología , Desempeño Psicomotor/fisiología , Trastornos de la Sensación/fisiopatología , Trastorno Depresivo Mayor/complicaciones , Femenino , Humanos , Masculino , Persona de Mediana Edad , Proyectos PilotoRESUMEN
Visual disturbance is one of the hallmarks of multiple sclerosis (MS), yet clinical neuropsychologists rarely quantitatively assess visual acuity using standardized and norm-referenced measures. This is a significant oversight because disturbances in visual acuity can have an obvious and profound impact on neuropsychological tests which rely upon visual attention and/or scanning. This study investigated the relationship between corrected visual acuity and a widely used measure of visual attention and incidental learning in a group of 35 patients with MS. Regression analysis indicated that corrected visual acuity accounted for 21.3% of the variance in a Coding subtest. The results suggest neuropsychologists and other health care providers should exercise caution in interpreting visually based tests for patients with MS and should assess visual acuity with standardized and norm-referenced measures.
Asunto(s)
Atención/fisiología , Aprendizaje/fisiología , Trastornos de la Visión/rehabilitación , Agudeza Visual/fisiología , Adulto , Evaluación de la Discapacidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Esclerosis Múltiple/complicaciones , Pruebas Neuropsicológicas , Estimulación Luminosa/métodos , Estadística como Asunto , Trastornos de la Visión/etiología , Pruebas de Visión/métodosRESUMEN
Healthcare for poor children, also known as Medicaid, is disproportionately relied upon by citizens of poor states such as New Mexico, where (a) there are more unintended pregnancies, (b) domestic violence during and after pregnancies occurs with regularity, (c) youth substance use is much more common, (d) crime rates are some of the worst in the country, (e) many never graduate from high school, and (f) incarceration is often inevitable. Yet, there is a dearth of research into the neuropsychological health of these children. Meanwhile, nonneuropsychologists working for managed care organizations routinely deny authorization for neuropsychological testing based on a lack of medical necessity. The present article addresses the question of neuropsychological medical necessity using community-based neuropsychological data from New Mexico collected on Medicaid and non-Medicaid youth via retroactive chart review. Downstream fiscal implications that are related to the eventual cost of mental illness and crime among those with poor neuropsychological health are discussed.
Asunto(s)
Disfunción Cognitiva/epidemiología , Entrevista Psicológica , Delincuencia Juvenil/estadística & datos numéricos , Medicaid/estadística & datos numéricos , Trastornos Mentales/epidemiología , Modelos Estadísticos , Trastornos del Neurodesarrollo/epidemiología , Pruebas Neuropsicológicas/estadística & datos numéricos , Complicaciones del Embarazo/epidemiología , Escalas de Wechsler/estadística & datos numéricos , Adolescente , Adulto , Niño , Preescolar , Femenino , Humanos , Masculino , Madres/estadística & datos numéricos , New Mexico/epidemiología , Embarazo , Embarazo no Planeado , Estudios Retrospectivos , Estados Unidos/epidemiología , Adulto JovenRESUMEN
Nocardia infection is a rare bacterial disorder that tends to affect the lungs and, in immunocompromised individuals, may progress to the brain. The brief, consecutive neuropsychological and neurobehavioral data of a 49-year-old male who developed multiple nocardia-related brain abscesses in the left frontal, occipital, and right cerebellar areas are reviewed. Neuropsychological findings indicated that he maintained mild-to-moderate impairments, primarily in executive functions, upon follow-up evaluation 43 days subsequent to baseline evaluation. This case demonstrates the utility of brief, serial neuropsychological screening in tracking the progression of an infectious process for the purposes of treatment planning and disposition.
Asunto(s)
Absceso Encefálico , Trastornos del Conocimiento/etiología , Nocardiosis/complicaciones , Absceso Encefálico/patología , Trastornos del Conocimiento/patología , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Nocardiosis/patología , Solución de Problemas/fisiología , Tomografía Computarizada por Rayos X/métodosRESUMEN
The present study assessed the ability of the Dean-Woodcock Sensory-Motor Battery (DWSMB) to distinguish between normal subjects and neurologically impaired individuals. Scores from the subtests of the DWSMB for 250 normal and 250 neurologically impaired individuals were randomly assigned to two equal groups to allow for cross-validation. The DWSMB was able to correctly identify 92.8% of the cases, identifying 94.4% of the normal population and 91.2% of the neurologically impaired subjects. The cross-validation correctly identified 87.2% of the total cases, identifying 91.2% of the normal subjects and 83.2% of the neurologically impaired subjects. An additional discriminant analysis indicated that the DWSMB correctly identified the following cases: 44.9% cardio-vascular accidents, 66.7% multiple sclerosis, 40% seizures, 42% traumatic brain injuries, 62.7% dementia, and 54.5% Parkinson's disease. The results add to the validity of the DWSMB by providing evidence of its ability to differentiate between neurologically impaired and normal individuals.
Asunto(s)
Encefalopatías/diagnóstico , Corteza Cerebral/fisiopatología , Pruebas Neuropsicológicas , Percepción/fisiología , Desempeño Psicomotor/fisiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Encefalopatías/fisiopatología , Encefalopatías/psicología , Niño , Preescolar , Análisis Discriminante , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Reproducibilidad de los ResultadosRESUMEN
The estimation of premorbid general intellectual functioning using word reading tests has a rich history of validation and is a common assessment practice for neuropsychologists. What is less well-researched is the approach used to estimate premorbid functioning of non-intellectual domains, such as executive functions, including verbal fluency. The current study evaluated this relationship with 41 adult college students who completed the Word Reading subtest of the Wechsler Individual Achievement Test-Second Edition (WIAT-II) and the Verbal Fluency test from the Delis-Kaplan Executive Function System (D-KEFS). Path analysis indicated that only Letter Fluency (a measure of phonemic fluency) was statistically significantly related to Word Reading and the relationship was somewhat weak. The relationship between Category Fluency (a measure of semantic fluency) and Category Switching (a measure of verbal fluency cognitive set-shifting) to Word Reading was nonsignificant. Participants also completed the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III), and as expected a strong relationship was found between Word Reading and the Verbal IQ (VIQ), Performance IQ (PIQ), and Full Scale Intelligence Quotient (FSIQ). Results of this study strongly suggest that caution be exercised when extrapolating an estimate of premorbid verbal fluency abilities from measures of word reading.
Asunto(s)
Lectura , Conducta Verbal/fisiología , Vocabulario , Adolescente , Atención/fisiología , Función Ejecutiva , Femenino , Humanos , Inteligencia , Pruebas de Inteligencia , Masculino , Valor Predictivo de las Pruebas , Adulto JovenRESUMEN
Children with fetal alcohol spectrum disorder (FASD) often present with comorbid attention-deficit hyperactivity disorder (ADHD), which can complicate diagnosis and treatment planning. This study investigated the cognitive and adaptive profiles of 81 children with ADHD/FASD and 147 children with ADHD. Multivariate analysis of variance and follow-up discriminant analysis indicated that the two groups had similar profiles on the Wechsler Intelligence Scale for Children-Fourth Edition and Vineland Adaptive Behavior Scales, although the children with comorbid ADHD/FASD demonstrated significantly more impairment in verbal ability, perceptual reasoning, working memory, processing speed, and overall adaptive skills. The results suggested that when compared with children with ADHD alone, children with ADHD/FASD exhibit significantly more impaired cognitive processing and adaptive skill deficits that are essential for school success and healthy social, behavioral, and emotional functioning. Research evaluating the profiles of these groups is likely to facilitate earlier and more accurate diagnosis and intervention.
Asunto(s)
Adaptación Psicológica/fisiología , Trastorno por Déficit de Atención con Hiperactividad/fisiopatología , Cognición/fisiología , Trastornos del Espectro Alcohólico Fetal/fisiopatología , Adolescente , Escala de Evaluación de la Conducta , Niño , Femenino , Humanos , Masculino , Análisis Multivariante , Factores de Riesgo , Escalas de WechslerRESUMEN
Moyamoya disease is a rare progressive cerebrovascular disorder that can be congenital or acquired and involves progressive stenosis and occlusion of cerebral arteries. The brain through compensatory angeogenesis then attempts to compensate for ischemia by producing a local network of tiny blood vessels, which appear cloud-like on angiograms. Consistent with multifocal or diffuse areas of ischemia, people with moyamoya often have multiple areas of cognitive impairment. A thorough literature review of the neuropsychological profile in individuals diagnosed with moyamoya disease is provided. Medical and neuropsychological/neurobehavioral data of a middle-aged woman with moyamoya disease is also described. The patient (MA) suffered an embolic shower with insult to both cerebral hemispheres. Neuropsychological results suggested a multifocal decline, with both cortical and subcortical involvement. Data were consistent with impairments in attention, concentration, executive skills, processing speed, and memory encoding and retrieval, with relatively spared aspects of memory and language skills. This case study supports the literature and provides an additional example of the neuropsychological profile and deficit pattern of an individual with moyamoya following an embolic stroke shower.
Asunto(s)
Enfermedad de Moyamoya , Adulto , Trastornos del Conocimiento/diagnóstico , Trastornos del Conocimiento/etiología , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Enfermedad de Moyamoya/complicaciones , Enfermedad de Moyamoya/cirugía , Pruebas Neuropsicológicas , Tomógrafos Computarizados por Rayos XRESUMEN
The current study examined the performance of college students (N = 63) on the Coding subtest of the Wechsler Adult Intelligence Scale-Third Edition and examined whether differences in performance could in part be explained by performance on the Delis-Kaplan Executive Functions System Trail-Making Test. The results of a multiple regression analysis indicated that performance on Coding was correlated most with Letter-Number Sequencing and to a lesser extent with Visual Scanning and with Number Sequencing approaching significance. There was no significant relationship with Letter Sequencing or Motor Speed. The three significant predictor variables were then entered into a stepwise hierarchical regression analysis. Subsequent models using Visual Scanning and Number Sequencing did not improve the predictive value of the model. These results are consistent with other recent reports suggesting that performance on Coding taps cognitive skills and abilities beyond that of simple motor speed or paired-associative learning. The findings also suggest a limited improvement in understanding test performance using a process analysis approach.
Asunto(s)
Función Ejecutiva/fisiología , Escalas de Wechsler , Adolescente , Adulto , Interpretación Estadística de Datos , Femenino , Humanos , Modelos Lineales , Masculino , Modelos Estadísticos , Desempeño Psicomotor , Reproducibilidad de los Resultados , Prueba de Secuencia Alfanumérica , Adulto JovenRESUMEN
Alien hand syndrome is a term used to describe a variety of rare conditions in which uncontrolled behavior or feelings of strangeness are felt in one extremity, most commonly the left hand. Etiology usually involves infarct of the right anterior or posterior cerebral arteries or cortical-basal degeneration. The medical and neuropsychological data of an elderly female who suffered a left middle cerebral artery stroke with resulting right-sided alien hand sign is presented. Neuropsychological assessment revealed declines in visual- and perceptual-based abilities and right-sided motor and sensory abilities consistent with the affected areas indicated on neuroimaging. This case demonstrates the utility of neuropsychological assessment in patients with unusual sensory/motor presentations.
Asunto(s)
Fenómeno de la Extremidad Ajena/complicaciones , Fenómeno de la Extremidad Ajena/diagnóstico , Trastornos del Conocimiento/etiología , Anciano , Fenómeno de la Extremidad Ajena/etiología , Trastornos del Conocimiento/diagnóstico , Femenino , Lateralidad Funcional , Humanos , Imagen por Resonancia Magnética , Pruebas Neuropsicológicas , Lóbulo Parietal/patología , Accidente Cerebrovascular/complicacionesRESUMEN
The purpose of this study was to examine the presence of finger agnosia in patients with Alzheimer's disease (AD) and to determine if level of finger agnosia was related to cognitive impairment. Finger agnosia is a sensitive measure of cerebral impairment and is associated with neurofunctional areas implicated in AD. Using a standardized and norm-referenced approach, results indicated that patients with AD evidenced significantly decreased performance on tests of bilateral finger agnosia compared with healthy age-matched controls. Finger agnosia was predictive of cognitive dysfunction on four of seven domains, including: Crystallized Language, Fluid Processing, Associative Learning, and Processing Speed. Results suggest that measures of finger agnosia, a short and simple test, may be useful in the early detection of AD.
Asunto(s)
Agnosia/etiología , Enfermedad de Alzheimer/complicaciones , Trastornos del Conocimiento/etiología , Anciano , Anciano de 80 o más Años , Agnosia/diagnóstico , Trastornos del Conocimiento/diagnóstico , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas NeuropsicológicasRESUMEN
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) typically exhibits a pattern of behavioral deficits, impairment in academic achievement, and cognitive processing, and presents with sensory-motor deficits. This study examined the relationships between sensory-motor tasks, cognitive processing, and academic achievement for a group of 67 children with ADHD. Strong canonical correlations emerged between sensory-motor functioning and academic achievement (.93) and sensory-motor functioning and cognitive processing (.98). An analysis of the redundancy coefficient showed that sensory-motor skills accounted for 65% of the variance in the achievement variables and 31% of the variance in the cognitive processing variables. The strong relationship between sensory-motor skills and higher order cognitive processes indicates that early assessment of sensory-motor skills may be useful in the identification of subsequent deficits in academic performance. Neuropsychologists should carefully consider the contribution of sensory-motor functioning to the more widely studied and assessed constructs of academic, behavioral, and emotional problems in children with ADHD.
Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad/psicología , Cognición , Desempeño Psicomotor , Adolescente , Niño , Estudios de Cohortes , Escolaridad , Femenino , Humanos , Masculino , Estadística como AsuntoRESUMEN
The ability to differentiate between neurologically impaired and normal individuals is an important component in a valid neuropsychological battery. However, limited research exists regarding the ability of sensory-motor batteries to differentiate between the two groups. This study used Classification and Regression Tree Analysis (CART) to identify which measures of sensory-motor functioning from the Dean-Woodcock Sensory Motor Battery (DWSMB) would best differentiate between neurologically impaired and normal individuals, as well as identify which subtests would provide the best pathognomic power. The results revealed that a number of clinically useful nodes emerged that enabled the differentiation between groups with a small number of tasks. The primary separation variable was the Gait and Station subtest, a measure of subcortical motor functioning. Auditory Acuity and Clock Construction also provide important pathognomic information. A cross validation was conducted to determine the integrity of the generated decision tree, and results revealed that the generated model correctly predicted 84.5% of the normal group and 71.4% of the neurologically impaired sample. The results from the present analysis provides further evidence for the construct validity of the DWSMB.
Asunto(s)
Árboles de Decisión , Pruebas Neuropsicológicas , Desempeño Psicomotor/fisiología , Trastornos Somatosensoriales/clasificación , Trastornos Somatosensoriales/diagnóstico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valores de Referencia , Análisis de Regresión , Reproducibilidad de los Resultados , Sensación/fisiología , Sensibilidad y EspecificidadAsunto(s)
Inhibidores de la Angiogénesis/administración & dosificación , Anticuerpos Monoclonales Humanizados/administración & dosificación , Neovascularización Coroidal/tratamiento farmacológico , Adulto , Anciano , Anciano de 80 o más Años , Bevacizumab , Neovascularización Coroidal/diagnóstico , Femenino , Angiografía con Fluoresceína , Humanos , Inyecciones Intravítreas , Degeneración Macular/diagnóstico , Degeneración Macular/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Retratamiento , Líquido Subretiniano , Tomografía de Coherencia Óptica , Resultado del Tratamiento , Factor A de Crecimiento Endotelial Vascular/antagonistas & inhibidores , Agudeza Visual/fisiologíaRESUMEN
The General Ability Measure for Adults (GAMA; Naglieri & Bardos, 1997) is a nonverbal brief measure of cognitive ability. Brief measures of cognitive ability are important in the assessment of individuals with impaired or limited test-taking skills. A sample of 50 adults with sudden-onset neurological impairment was compared to a demographically matched control group. The neurologically impaired adults scored significantly lower (t (98) = 6.2, p < .001) on the GAMA than did the control group. The Kaufman Brief Intelligence Test (K-BIT; Kaufman & Kaufman, 1990) was also administered to the neurologically impaired group. The K-BIT scores correlated significantly with the GAMA Total IQ score (K-BIT IQ, r = .59, p < .001; Matrices, r = .64, p < .001; Vocabulary, r = .30, p < .05). The study's findings suggested that the GAMA can be used successfully as a screening measure of cognitive ability with individuals with neurological impairment using a nonverbal means that is not dependent on prior academic knowledge or linguistic ability.
Asunto(s)
Cognición/fisiología , Pruebas de Inteligencia , Enfermedades del Sistema Nervioso/fisiopatología , Pruebas Neuropsicológicas , Adulto , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas/normas , Pruebas Neuropsicológicas/estadística & datos numéricos , Reproducibilidad de los Resultados , Sensibilidad y EspecificidadRESUMEN
The factor structure of the Dean-Woodcock Sensory Motor Battery was examined using exploratory factor analysis with promax rotation. Participants (n = 1,651) were composed of 701 neurologically impaired individuals and 950 normal individuals. Three factors, accounting for almost 58.2% of the total test variation, emerged from the data and were labeled Simple Sensory Skills, Motor and Complex Sensory Skills, and Subcortical Motor Skills and Auditory/Visual Acuity. Hypothesized cross loadings were present, especially between the first two factors, which highlighted the parallel nature of sensory-motor skills. The third factor demonstrated the least amount of cross loadings, which reinforced the demarcation of cortical and subcortical motor skills measured by the DWSMB. The results also indicated that the factors were separated by the complexity of the cortical sensory-motor tasks. The factor structure, combined with an analysis of the interfactor correlations, provides evidence for construct validity of the DWSMB.