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1.
Preclinical pharmacokinetics and metabolism of MAK683, a clinical stage selective oral embryonic ectoderm development (EED) inhibitor for cancer treatment.
Xenobiotica;
52(1): 65-78, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34761729
2.
All Ion Differential Analysis Refines the Detection of Terminal and Internal Diagnostic Fragment Ions for the Characterization of Biologics Product-Related Variants and Impurities by Middle-down Mass Spectrometry.
Anal Chem;
91(14): 8845-8852, 2019 07 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31187983
3.
Restoring the biological activity of crizanlizumab at physiological conditions through a pH-dependent aspartic acid isomerization reaction.
MAbs;
15(1): 2151075, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36519228
4.
Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery.
J Mass Spectrom;
52(4): 210-217, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28152561
5.
Micropreparative isolation and NMR structure elucidation of metabolites of the drug candidate 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-yn-1-yloxy) quinazolin-2(1H)-one from rat bile and urine.
J Chromatogr B Analyt Technol Biomed Life Sci;
989: 1-10, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25797717
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