Búsqueda | Portal de Búsqueda de la BVS España

1.

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

Chio, Iok In Christine; Jafarnejad, Seyed Mehdi; Ponz-Sarvise, Mariano; Park, Youngkyu; Rivera, Keith; Palm, Wilhelm; Wilson, John; Sangar, Vineet; Hao, Yuan; Öhlund, Daniel; Wright, Kevin; Filippini, Dea; Lee, Eun Jung; Da Silva, Brandon; Schoepfer, Christina; Wilkinson, John Erby; Buscaglia, Jonathan M; DeNicola, Gina M; Tiriac, Herve; Hammell, Molly; Crawford, Howard C; Schmidt, Edward E; Thompson, Craig B; Pappin, Darryl J; Sonenberg, Nahum; Tuveson, David A.

Cell; 166(4): 963-976, 2016 Aug 11.

Artículo en Inglés | MEDLINE | ID: mdl-27477511

2.

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.

Emerling, Brooke M; Hurov, Jonathan B; Poulogiannis, George; Tsukazawa, Kazumi S; Choo-Wing, Rayman; Wulf, Gerburg M; Bell, Eric L; Shim, Hye-Seok; Lamia, Katja A; Rameh, Lucia E; Bellinger, Gary; Sasaki, Atsuo T; Asara, John M; Yuan, Xin; Bullock, Andrea; Denicola, Gina M; Song, Jiaxi; Brown, Victoria; Signoretti, Sabina; Cantley, Lewis C.

Cell; 155(4): 844-57, 2013 Nov 07.

Artículo en Inglés | MEDLINE | ID: mdl-24209622

3.

Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges.

Torrente, Laura; DeNicola, Gina M.

Annu Rev Pharmacol Toxicol; 62: 279-300, 2022 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-34499527

4.

Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools.

Pezacki, Aidan T; Matier, Carson D; Gu, Xingxing; Kummelstedt, Eric; Bond, Sarah E; Torrente, Laura; Jordan-Sciutto, Kelly L; DeNicola, Gina M; Su, Timothy A; Brady, Donita C; Chang, Christopher J.

Proc Natl Acad Sci U S A; 119(43): e2202736119, 2022 10 25.

Artículo en Inglés | MEDLINE | ID: mdl-36252013

5.

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w.

Van Oss, S Branden; Parikh, Saurin Bipin; Castilho Coelho, Nelson; Wacholder, Aaron; Belashov, Ivan; Zdancewicz, Sara; Michaca, Manuel; Xu, Jiazhen; Kang, Yun Pyo; Ward, Nathan P; Yoon, Sang Jun; McCourt, Katherine M; McKee, Jake; Ideker, Trey; VanDemark, Andrew P; DeNicola, Gina M; Carvunis, Anne-Ruxandra.

J Biol Chem; 298(12): 102697, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36379252

6.

A PI3K gene expression signature predicts for recurrence in early-stage non-small cell lung cancer treated with stereotactic body radiation therapy.

Sebastian, Nikhil T; Webb, Amy; Shilo, Konstantin; Robb, Ryan; Xu-Welliver, Meng; Haglund, Karl; Brownstein, Jeremy; DeNicola, Gina M; Shen, Changxian; Williams, Terence M.

Cancer; 129(24): 3971-3977, 2023 12 15.

Artículo en Inglés | MEDLINE | ID: mdl-37560930

7.

Long-sought mediator of vitamin K recycling discovered.

Ward, Nathan P; DeNicola, Gina M.

Nature; 608(7924): 673-674, 2022 08.

Artículo en Inglés | MEDLINE | ID: mdl-35922487

8.

Cancer's Fuel Choice: New Flavors for a Picky Eater.

DeNicola, Gina M; Cantley, Lewis C.

Mol Cell; 60(4): 514-23, 2015 Nov 19.

Artículo en Inglés | MEDLINE | ID: mdl-26590711

9.

Genetic tools for the stable overexpression of circular RNAs.

Mecozzi, Nicol; Nenci, Arianna; Vera, Olga; Bok, Ilah; Falzone, Aimee; DeNicola, Gina M; Karreth, Florian A.

RNA Biol; 19(1): 353-363, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35289721

10.

The microbiome(s) and cancer: know thy neighbor(s).

González-Sánchez, Paloma; DeNicola, Gina M.

J Pathol; 254(4): 332-343, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-33723873

11.

Establishing a living biobank of patient-derived organoids of intraductal papillary mucinous neoplasms of the pancreas.

Beato, Francisca; Reverón, Dayana; Dezsi, Kaleena B; Ortiz, Antonio; Johnson, Joseph O; Chen, Dung-Tsa; Ali, Karla; Yoder, Sean J; Jeong, Daniel; Malafa, Mokenge; Hodul, Pamela; Jiang, Kun; Centeno, Barbara A; Abdalah, Mahmoud A; Balasi, Jodi A; Tassielli, Alexandra F; Sarcar, Bhaswati; Teer, Jamie K; DeNicola, Gina M; Permuth, Jennifer B; Fleming, Jason B.

Lab Invest; 101(2): 204-217, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33037322

12.

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.

Mullarky, Edouard; Lucki, Natasha C; Beheshti Zavareh, Reza; Anglin, Justin L; Gomes, Ana P; Nicolay, Brandon N; Wong, Jenny C Y; Christen, Stefan; Takahashi, Hidenori; Singh, Pradeep K; Blenis, John; Warren, J David; Fendt, Sarah-Maria; Asara, John M; DeNicola, Gina M; Lyssiotis, Costas A; Lairson, Luke L; Cantley, Lewis C.

Proc Natl Acad Sci U S A; 113(7): 1778-83, 2016 Feb 16.

Artículo en Inglés | MEDLINE | ID: mdl-26831078

13.

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.

DeNicola, Gina M; Karreth, Florian A; Humpton, Timothy J; Gopinathan, Aarthi; Wei, Cong; Frese, Kristopher; Mangal, Dipti; Yu, Kenneth H; Yeo, Charles J; Calhoun, Eric S; Scrimieri, Francesca; Winter, Jordan M; Hruban, Ralph H; Iacobuzio-Donahue, Christine; Kern, Scott E; Blair, Ian A; Tuveson, David A.

Nature; 475(7354): 106-9, 2011 Jul 06.

Artículo en Inglés | MEDLINE | ID: mdl-21734707

14.

C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

Karreth, Florian A; DeNicola, Gina M; Winter, Stephen P; Tuveson, David A.

Mol Cell; 36(3): 477-86, 2009 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-19917255

15.

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.

Massie, Charles E; Lynch, Andy; Ramos-Montoya, Antonio; Boren, Joan; Stark, Rory; Fazli, Ladan; Warren, Anne; Scott, Helen; Madhu, Basetti; Sharma, Naomi; Bon, Helene; Zecchini, Vinny; Smith, Donna-Michelle; Denicola, Gina M; Mathews, Nik; Osborne, Michelle; Hadfield, James; Macarthur, Stewart; Adryan, Boris; Lyons, Scott K; Brindle, Kevin M; Griffiths, John; Gleave, Martin E; Rennie, Paul S; Neal, David E; Mills, Ian G.

EMBO J; 30(13): 2719-33, 2011 May 20.

Artículo en Inglés | MEDLINE | ID: mdl-21602788

16.

MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability.

Jasani, Neel; Xu, Xiaonan; Posorske, Benjamin; Kim, Yumi; Vera, Olga; Tsai, Kenneth Y; DeNicola, Gina M; Karreth, Florian A.

bioRxiv; 2024 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-38659816

17.

Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC.

Ward, Nathan P; Yoon, Sang Jun; Flynn, Tyce; Sherwood, Amanda M; Olley, Maddison A; Madej, Juliana; DeNicola, Gina M.

Nat Commun; 15(1): 4244, 2024 May 18.

Artículo en Inglés | MEDLINE | ID: mdl-38762605

18.

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice.

Gopinathan, Aarthi; Denicola, Gina M; Frese, Kristopher K; Cook, Natalie; Karreth, Florian A; Mayerle, Julia; Lerch, Markus M; Reinheckel, Thomas; Tuveson, David A.

Gut; 61(6): 877-84, 2012 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-22157328

19.

Quantification and Tracing of Stable Isotope into Cysteine and Glutathione.

Kang, Yun Pyo; DeNicola, Gina M.

Methods Mol Biol; 2675: 51-63, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37258755

20.

Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.

Yoon, Sang Jun; Combs, Joseph A; Falzone, Aimee; Prieto-Farigua, Nicolas; Caldwell, Samantha; Ackerman, Hayley D; Flores, Elsa R; DeNicola, Gina M.

Cancer Res; 83(9): 1426-1442, 2023 05 02.

Artículo en Inglés | MEDLINE | ID: mdl-36862034

Portal de Búsqueda de la BVS España

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: