Detalles de la búsqueda
1.
Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency.
Adv Exp Med Biol;
1415: 353-358, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37440056
2.
Preservation of endoplasmic reticulum (ER) Ca2+ stores by deletion of inositol-1,4,5-trisphosphate receptor type 1 promotes ER retrotranslocation, proteostasis, and protein outer segment localization in cyclic nucleotide-gated channel-deficient cone photoreceptors.
FASEB J;
35(6): e21579, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33960001
3.
Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency.
FASEB J;
34(5): 6335-6350, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32173907
4.
The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia.
Int J Mol Sci;
22(1)2020 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33374621
5.
Deficiency of type 2 iodothyronine deiodinase reduces necroptosis activity and oxidative stress responses in retinas of Leber congenital amaurosis model mice.
FASEB J;
: fj201800484RR, 2018 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29874126
6.
Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.
J Biol Chem;
292(27): 11189-11205, 2017 07 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28495882
7.
Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.
FASEB J;
31(8): 3425-3438, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28428265
8.
Overexpression of Type 3 Iodothyronine Deiodinase Reduces Cone Death in the Leber Congenital Amaurosis Model Mice.
Adv Exp Med Biol;
1074: 125-131, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29721936
9.
The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility.
J Biol Chem;
291(16): 8721-34, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26893377
10.
Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia.
Hum Mol Genet;
24(13): 3699-707, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25855802
11.
Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.
FASEB J;
30(12): 4313-4325, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27623928
12.
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.
Proc Natl Acad Sci U S A;
111(9): 3602-7, 2014 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24550448
13.
cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.
J Biol Chem;
290(34): 20880-20892, 2015 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26124274
14.
Thyroid Hormone Signaling and Cone Photoreceptor Viability.
Adv Exp Med Biol;
854: 613-8, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26427466
15.
Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study.
Hum Mol Genet;
22(19): 3906-19, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23740940
16.
cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function.
J Neurosci;
33(37): 14939-48, 2013 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24027293
17.
Cones respond to light in the absence of transducin ß subunit.
J Neurosci;
33(12): 5182-94, 2013 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23516284
18.
Exploration of cone cyclic nucleotide-gated channel-interacting proteins using affinity purification and mass spectrometry.
Adv Exp Med Biol;
801: 57-65, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24664681
19.
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.
J Biol Chem;
287(22): 18018-29, 2012 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22493484
20.
Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy.
Hum Mol Genet;
20(16): 3161-75, 2011 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21576125