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1.

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.

Nguyen, Phuong H; Ramamoorthy, Ayyalusamy; Sahoo, Bikash R; Zheng, Jie; Faller, Peter; Straub, John E; Dominguez, Laura; Shea, Joan-Emma; Dokholyan, Nikolay V; De Simone, Alfonso; Ma, Buyong; Nussinov, Ruth; Najafi, Saeed; Ngo, Son Tung; Loquet, Antoine; Chiricotto, Mara; Ganguly, Pritam; McCarty, James; Li, Mai Suan; Hall, Carol; Wang, Yiming; Miller, Yifat; Melchionna, Simone; Habenstein, Birgit; Timr, Stepan; Chen, Jiaxing; Hnath, Brianna; Strodel, Birgit; Kayed, Rakez; Lesné, Sylvain; Wei, Guanghong; Sterpone, Fabio; Doig, Andrew J; Derreumaux, Philippe.

Chem Rev; 121(4): 2545-2647, 2021 02 24.

Artículo en Inglés | MEDLINE | ID: mdl-33543942

2.

Raman Spectroscopy to Monitor Post-Translational Modifications and Degradation in Monoclonal Antibody Therapeutics.

McAvan, Bethan S; Bowsher, Leo A; Powell, Thomas; O'Hara, John F; Spitali, Mariangela; Goodacre, Royston; Doig, Andrew J.

Anal Chem; 92(15): 10381-10389, 2020 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-32614170

3.

Quantification of protein glycation using vibrational spectroscopy.

McAvan, Bethan S; France, Aidan P; Bellina, Bruno; Barran, Perdita E; Goodacre, Royston; Doig, Andrew J.

Analyst; 145(10): 3686-3696, 2020 May 21.

Artículo en Inglés | MEDLINE | ID: mdl-32319996

4.

Effect of IAPP on the proteome of cultured Rin-5F cells.

Miraee-Nedjad, Samaneh; Sims, Paul F G; Schwartz, Jean-Marc; Doig, Andrew J.

BMC Biochem; 19(1): 9, 2018 11 12.

Artículo en Inglés | MEDLINE | ID: mdl-30419808

5.

Determination of Protein Secondary Structure from Infrared Spectra Using Partial Least-Squares Regression.

Wilcox, Kieaibi E; Blanch, Ewan W; Doig, Andrew J.

Biochemistry; 55(27): 3794-802, 2016 07 12.

Artículo en Inglés | MEDLINE | ID: mdl-27322779

6.

Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies.

Davies, Heather S; Singh, Prabha; Deckert-Gaudig, Tanja; Deckert, Volker; Rousseau, Karine; Ridley, Caroline E; Dowd, Sarah E; Doig, Andrew J; Pudney, Paul D A; Thornton, David J; Blanch, Ewan W.

Anal Chem; 88(23): 11609-11615, 2016 12 06.

Artículo en Inglés | MEDLINE | ID: mdl-27791356

7.

Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp.

Berthoumieu, Olivia; Nguyen, Phuong H; Castillo-Frias, Maria P Del; Ferre, Sabrina; Tarus, Bogdan; Nasica-Labouze, Jessica; Noël, Sabrina; Saurel, Olivier; Rampon, Claire; Doig, Andrew J; Derreumaux, Philippe; Faller, Peter.

Chemistry; 21(36): 12657-66, 2015 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-26179053

8.

Essentiality, protein-protein interactions and evolutionary properties are key predictors for identifying cancer-associated genes using machine learning.

Safadi, Amro; Lovell, Simon C; Doig, Andrew J.

Sci Rep; 14(1): 9199, 2024 04 22.

Artículo en Inglés | MEDLINE | ID: mdl-38649399

9.

Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.

Tait, Shirley; Dutta, Kaushik; Cowburn, David; Warwicker, Jim; Doig, Andrew J; McCarthy, John E G.

Proc Natl Acad Sci U S A; 107(41): 17627-32, 2010 Oct 12.

Artículo en Inglés | MEDLINE | ID: mdl-20880835

10.

Predicting congenital renal tract malformation genes using machine learning.

Kabir, Mitra; Stuart, Helen M; Lopes, Filipa M; Fotiou, Elisavet; Keavney, Bernard; Doig, Andrew J; Woolf, Adrian S; Hentges, Kathryn E.

Sci Rep; 13(1): 13204, 2023 08 14.

Artículo en Inglés | MEDLINE | ID: mdl-37580336

11.

The N-methylated peptide SEN304 powerfully inhibits Aß(1-42) toxicity by perturbing oligomer formation.

Amijee, Hozefa; Bate, Clive; Williams, Alun; Virdee, Jasmeet; Jeggo, Ross; Spanswick, David; Scopes, David I C; Treherne, J Mark; Mazzitelli, Sonia; Chawner, Ross; Eyers, Claire E; Doig, Andrew J.

Biochemistry; 51(42): 8338-52, 2012 Oct 23.

Artículo en Inglés | MEDLINE | ID: mdl-23025847

12.

Amyloid ß Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.

Nasica-Labouze, Jessica; Nguyen, Phuong H; Sterpone, Fabio; Berthoumieu, Olivia; Buchete, Nicolae-Viorel; Coté, Sébastien; De Simone, Alfonso; Doig, Andrew J; Faller, Peter; Garcia, Angel; Laio, Alessandro; Li, Mai Suan; Melchionna, Simone; Mousseau, Normand; Mu, Yuguang; Paravastu, Anant; Pasquali, Samuela; Rosenman, David J; Strodel, Birgit; Tarus, Bogdan; Viles, John H; Zhang, Tong; Wang, Chunyu; Derreumaux, Philippe.

Chem Rev; 115(9): 3518-63, 2015 May 13.

Artículo en Inglés | MEDLINE | ID: mdl-25789869

13.

Viral Involvement in Alzheimer's Disease.

Sait, Ahmad; Angeli, Cristian; Doig, Andrew J; Day, Philip J R.

ACS Chem Neurosci; 12(7): 1049-1060, 2021 04 07.

Artículo en Inglés | MEDLINE | ID: mdl-33687205

14.

Properties and identification of antibiotic drug targets.

Bakheet, Tala M; Doig, Andrew J.

BMC Bioinformatics; 11: 195, 2010 Apr 20.

Artículo en Inglés | MEDLINE | ID: mdl-20406434

15.

Accurate determination of protein secondary structure content from Raman and Raman optical activity spectra.

Kinalwa, Myra N; Blanch, Ewan W; Doig, Andrew J.

Anal Chem; 82(15): 6347-9, 2010 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-20669990

16.

Properties and identification of human protein drug targets.

Bakheet, Tala M; Doig, Andrew J.

Bioinformatics; 25(4): 451-7, 2009 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-19164304

17.

Deconvolution of conformational exchange from Raman spectra of aqueous RNA nucleosides.

Wilson, Alex L; Outeiral, Carlos; Dowd, Sarah E; Doig, Andrew J; Popelier, Paul L A; Waltho, Jonathan P; Almond, Andrew.

Commun Chem; 3(1): 56, 2020 May 06.

Artículo en Inglés | MEDLINE | ID: mdl-36703475

18.

SitesIdentify: a protein functional site prediction tool.

Bray, Tracey; Chan, Pedro; Bougouffa, Salim; Greaves, Richard; Doig, Andrew J; Warwicker, Jim.

BMC Bioinformatics; 10: 379, 2009 Nov 18.

Artículo en Inglés | MEDLINE | ID: mdl-19922660

19.

Inhibitors of protein aggregation and toxicity.

Amijee, Hozefa; Madine, Jill; Middleton, David A; Doig, Andrew J.

Biochem Soc Trans; 37(Pt 4): 692-6, 2009 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-19614577

20.

Fewer academics could be the answer to insufficient grants.

Doig, Andrew.

Nature; 453(7198): 978, 2008 Jun 19.

Artículo en Inglés | MEDLINE | ID: mdl-18563127

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