Detalles de la búsqueda
1.
PI3Kδ and mTOR dual inhibitors: Design, synthesis and anticancer evaluation of 3-substituted aminomethylquinoline analogues.
Bioorg Chem;
147: 107323, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38583254
2.
Sesquiterpene from Artemisia argyi seed extracts: A new anti-acute peritonitis agent that suppresses the MAPK pathway and promotes autophagy.
Inflammopharmacology;
32(1): 447-460, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37578619
3.
Fluorescence probe for real-time malonaldehyde detection in epilepsy model.
Analyst;
149(1): 196-204, 2023 Dec 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38013467
4.
Design, synthesis and biological evaluation of novel tubulin inhibitors targeting colchicine sites.
Bioorg Med Chem Lett;
83: 129166, 2023 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36736495
5.
Design, synthesis, and biological activity evaluation of novel tubulin polymerization inhibitors based on pyrimidine ring skeletons.
Bioorg Med Chem Lett;
84: 129195, 2023 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36828299
6.
Recent advances in small-molecule fluorescent probes for studying ferroptosis.
Chem Soc Rev;
51(18): 7752-7778, 2022 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36052828
7.
Alterations in the gut microbiome and metabolome profiles of septic rats treated with aminophylline.
J Transl Med;
20(1): 69, 2022 02 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35115021
8.
2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response.
Bioorg Chem;
120: 105625, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35078046
9.
Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colchicine binding site inhibitors.
J Enzyme Inhib Med Chem;
37(1): 652-665, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35109719
10.
Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors.
J Enzyme Inhib Med Chem;
37(1): 339-354, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34979843
11.
The role of MOZ/KAT6A in hematological malignancies and advances in MOZ/KAT6A inhibitors.
Pharmacol Res;
174: 105930, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34626770
12.
Synthesis and biological evaluation of new 2-methoxyestradiol derivatives: Potent inhibitors of angiogenesis and tubulin polymerization.
Bioorg Chem;
113: 104988, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34034135
13.
Discovery of novel sulfonamide-containing aminophosphonate derivatives as selective COX-2 inhibitors and anti-tumor candidates.
Bioorg Chem;
105: 104390, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33137555
14.
Discovery and development of novel rhodanine derivatives targeting enoyl-acyl carrier protein reductase.
Bioorg Med Chem;
27(8): 1509-1516, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30846404
15.
Design and biological evaluation of novel hybrids of 1, 5-diarylpyrazole and Chrysin for selective COX-2 inhibition.
Bioorg Med Chem;
26(14): 4264-4275, 2018 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30031652
16.
Design, synthesis and biological evaluation of pyrazolyl-nitroimidazole derivatives as potential EGFR/HER-2 kinase inhibitors.
Bioorg Med Chem Lett;
26(2): 677-683, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26652482
17.
Design, synthesis and molecular modeling of biquinoline-pyridine hybrids as a new class of potential EGFR and HER-2 kinase inhibitors.
Bioorg Med Chem Lett;
24(18): 4472-4476, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25172421
18.
Synthesis, biological evaluation, and molecular docking studies of novel 2-styryl-5-nitroimidazole derivatives containing 1,4-benzodioxan moiety as FAK inhibitors with anticancer activity.
Bioorg Med Chem;
22(11): 2947-54, 2014 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24792811
19.
Restoration of nNOS Expression Rescues Autistic-Like Phenotypes Through Normalization of AMPA Receptor-Mediated Neurotransmission.
Mol Neurobiol;
2024 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38329681
20.
A comprehensive review of natural product-derived compounds acting on P2X7R: The promising therapeutic drugs in disorders.
Phytomedicine;
128: 155334, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38554573