RESUMEN
Polyunsaturated fatty acids (PUFAs) found in microalgae, primarily omega-3 (ω-3) and omega-6 (ω-6) are essential nutrients with positive effects on diseases such as hyperlipidemia, atherosclerosis, and coronary risk. Researchers still seek improvement in PUFA yield at a large scale for better commercial prospects. This review summarizes advancements in microalgae PUFA research for their cost-effective production and potential applications. Moreover, it discusses the most promising cultivation modes using organic and inorganic sources. It also discusses biomass hydrolysates to increase PUFA production as an alternative and sustainable organic source. For cost-effective PUFA production, heterotrophic, mixotrophic, and photoheterotrophic cultivation modes are assessed with traditional photoautotrophic production modes. Also, mixotrophic cultivation has fascinating sustainable attributes over other trophic modes. Furthermore, it provides insight into growth phase (stage I) improvement strategies to accumulate biomass and the complementing effects of other stress-inducing strategies during the production phase (stage II) on PUFA enhancement under these cultivation modes. The role of an excessive or limiting range of salinity, nutrients, carbon source, and light intensity were the most effective parameter in stage II for accumulating higher PUFAs such as ω-3 and ω-6. This article outlines the commercial potential of microalgae for omega PUFA production. They reduce the risk of diabetes, cardiovascular diseases (CVDs), cancer, and hypertension and play an important role in their emerging role in healthy lifestyle management.
RESUMEN
Rapidly changing bioremediation prospects are key drive to develop sustainable options that can offer extra benefits rather than only environmental remediation. Algal remediating is gaining utmost attention due to its mesmerising sustainable features, removing odour and toxicity, co-remediating numerous common and emerging inorganic and organic pollutants from gaseous and aqueous environments, and yielding biomass for a range of valuable products refining. Moreover, it also improves carbon footprint via carbon-capturing offers a better option than any other non-algal process for several high CO2-emitting industries. Bio-uptake, bioadsorption, photodegradation, and biodegradation are the main mechanisms to remediate a range of common and emerging pollutants by various algae species. Bioadsorption was a dominant remediation mechanism among others implicating surface properties of pollutants and algal cell walls. Photodegradable pollutants were photodegraded by microalgae by adsorbing photons on the surface and intracellularly via stepwise photodissociation and breakdown. Biodegradation involves the transportation of selective pollutants intracellularly, and enzymes help to convert them into simpler non-toxic forms. Robust models are from the green microalgae group and are dominated by Chlorella species. This article compiles the advancements in microalgae-assisted pollutants remediation and value-addition under sustainable biorefinery prospects. Moreover, filling the knowledge gaps, and recommendations for developing an effective platform for emerging pollutants remediation and realization of commercial-scale algal bioremediation.