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Can J Neurol Sci ; 41(2): 253-9, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24534039

RESUMEN

INTRODUCTION: We conducted a retrospective chart review of 53 patients diagnosed with sporadic Inclusion Body Myositis (sIBM) who have been followed at the McMaster Neuromuscular Clinic since 1996. OBJECTIVES: We reviewed patient medical histories in order to compare our findings with similar cohorts, and analyzed quantitative strength data to determine functionality in guiding decisions related to gait assistive devices. METHODS: Patient information was acquired through retrospective clinic chart review. RESULTS: Our study found knee extension strength decreased significantly as patients transitioned to using more supportive gait assistive devices (P < 0.05). A decline to below 30 Nm was particularly indicative of the need for a preliminary device (i.e. cane)(P < 0.05). Falls and fear of falling poses a significant threat to patient physical well-being. The prevalence of dysphagia increased as patients required more supportive gait devices, and finally a significant negative correlation was found between time after onset and creatine kinase (CK) levels (P < 0.01). CONCLUSION: This study supports that knee extension strength may be a useful tool in advising patients concerning ambulatory assistance. Further investigations concerning gait assistive device use and patient history of falling would be beneficial in preventing future falls and improving long-term patient outcomes.


Asunto(s)
Trastornos de Deglución/fisiopatología , Deambulación Dependiente , Fuerza Muscular , Miositis por Cuerpos de Inclusión/fisiopatología , Equipo Ortopédico/estadística & datos numéricos , Silla de Ruedas/estadística & datos numéricos , Bastones/estadística & datos numéricos , Estudios de Cohortes , Creatina Quinasa/sangre , Creatinina/sangre , Trastornos de Deglución/etiología , Femenino , Ortesis del Pié/estadística & datos numéricos , Fuerza de la Mano , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Miositis por Cuerpos de Inclusión/complicaciones , Estudios Retrospectivos , Andadores/estadística & datos numéricos
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