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1.
Br J Surg ; 104(10): 1293-1306, 2017 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-28681962

RESUMEN

BACKGROUND: Pain present for at least 3 months after a surgical procedure is considered chronic postsurgical pain (CPSP) and affects 10-50 per cent of patients. Interventions for CPSP may focus on the underlying condition that indicated surgery, the aetiology of new-onset pain or be multifactorial in recognition of the diverse causes of this pain. The aim of this systematic review was to identify RCTs of interventions for the management of CPSP, and synthesize data across treatment type to estimate their effectiveness and safety. METHODS: MEDLINE, Embase, PsycINFO, CINAHL and the Cochrane Library were searched from inception to March 2016. Trials of pain interventions received by patients at 3 months or more after surgery were included. Risk of bias was assessed using the Cochrane risk-of-bias tool. RESULTS: Some 66 trials with data from 3149 participants were included. Most trials included patients with chronic pain after spinal surgery (25 trials) or phantom limb pain (21 trials). Interventions were predominantly pharmacological, including antiepileptics, capsaicin, epidural steroid injections, local anaesthetic, neurotoxins, N-methyl-d-aspartate receptor antagonists and opioids. Other interventions included acupuncture, exercise, postamputation limb liner, spinal cord stimulation, further surgery, laser therapy, magnetic stimulation, mindfulness-based stress reduction, mirror therapy and sensory discrimination training. Opportunities for meta-analysis were limited by heterogeneity. For all interventions, there was insufficient evidence to draw conclusions on effectiveness. CONCLUSION: There is a need for more evidence about interventions for CPSP. High-quality trials of multimodal interventions matched to pain characteristics are needed to provide robust evidence to guide management of CPSP.


Asunto(s)
Dolor Crónico/terapia , Dolor Postoperatorio/terapia , Terapia por Acupuntura , Terapia Conductista , Dolor Crónico/tratamiento farmacológico , Dolor Crónico/cirugía , Terapia Combinada , Terapia por Ejercicio , Humanos , Terapia por Láser , Dolor Postoperatorio/tratamiento farmacológico , Dolor Postoperatorio/cirugía , Estimulación de la Médula Espinal
2.
Int Nurs Rev ; 62(1): 28-35, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25440317

RESUMEN

AIM: The study aimed to identify the potential for aged care placements to deliver benefits for second year nursing students when conducted within a supportive framework with debriefing and critical reflection opportunities. BACKGROUND: Given the ageing population and complex care needs of aged care facility residents, exacerbated by the high prevalence of dementia, the healthcare workforce's ability to meet older people's care needs is paramount. Yet research shows that nursing students are disengaged from aged care. METHODS: Using a quasi-experimental mixed method design within an action research framework, 40 students were allocated a 3-week supported placement in 2011-2012 at one of the two intervention residential aged care facilities in Tasmania, Australia. Staff formed mentor action research groups in each facility and participated in a pre-placement capacity-building programme. Thirty-nine students were placed across 14 control facilities. Data were collected via meetings with students and pre-post placement questionnaires on placement experiences, attitudes and dementia knowledge. RESULTS: The intervention facility placement programme led to mentors and students being well prepared for the placement and to students experiencing enhanced teaching and learning derived from high levels of mentor support and increased autonomy. Students' knowledge, understanding and attitudes around aged care and dementia improved. DISCUSSION: Mentors working together within an action research framework can provide a supported residential aged care placement for nursing students that improves students' aged care attitudes and understandings. CONCLUSION AND IMPLICATIONS FOR NURSING AND HEALTH POLICY: Provision of quality, supported aged care student placements is vital to prepare a new generation of nurses who will have to deal with the complex chronic healthcare needs associated with an ageing population.


Asunto(s)
Demencia/enfermería , Bachillerato en Enfermería/organización & administración , Enfermería Geriátrica/educación , Hogares para Ancianos , Casas de Salud , Preceptoría/organización & administración , Estudiantes de Enfermería , Adulto , Anciano , Anciano de 80 o más Años , Competencia Clínica , Estudios de Cohortes , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Masculino , Mentores , Investigación en Evaluación de Enfermería , Investigación Metodológica en Enfermería , Tasmania , Adulto Joven
3.
Child Care Health Dev ; 40(4): 572-9, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-23663232

RESUMEN

BACKGROUND: Adolescents are routinely recognized as native to online technologies. However, we know from previous research that this familiarity does not often translate into its use for help-seeking around health. We designed this study to examine the experience of adolescents in using the Internet to access pain management information, specifically why some adolescents may be reluctant to use these resources. METHODS: Twenty-six healthy, school attending, adolescents aged between 14 and 17 years old were recruited to a qualitative study of focus groups. Seventeen participants were female and nine were male. Participation was limited to those who self-selected as frequent users of the Internet, but who were loath to use it as a resource for health information as we wished to explore reasons for non-use. All data were thematically analysed. RESULTS: Most participants reported using the Internet to seek health information at least once. Experiences with online content were typically negative and drawn on only when all other sources of information and pain coping were exhausted. Three themes emerged, Drivers of Internet use, Barriers, and Anxiety around use. Adolescent health websites were reported to be confusing, anxiety provoking and hard to negotiate. The Internet was judged to be less accessible than other forms of pain and health coping information. Secondary themes related to topic embarrassment, the strive for independence and reassurance, preferred information source failure, curiosity, website design, availability of OTC analgesics, effort, fear-provoking narratives, mistrust of quality of online content and pain-related anxiety. CONCLUSIONS: Counter to many positive reports of the health benefits of Internet use during information seeking, its value is questionable to some adolescents. Typical experience was anxiety provoking, unlikely to yield helpful results, and wasteful comparative to off-line resources for pain.


Asunto(s)
Conducta en la Búsqueda de Información , Internet , Dolor/psicología , Autocuidado/psicología , Adolescente , Conducta del Adolescente , Información de Salud al Consumidor , Inglaterra/epidemiología , Femenino , Conductas Relacionadas con la Salud , Conocimientos, Actitudes y Práctica en Salud , Humanos , Internet/estadística & datos numéricos , Masculino , Investigación Cualitativa , Calidad de la Atención de Salud , Autocuidado/estadística & datos numéricos , Encuestas y Cuestionarios
4.
Br J Anaesth ; 111(1): 59-63, 2013 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-23794646

RESUMEN

Psychological interventions are a mainstay of modern pain management practice and a recommended feature of a modern pain treatment service. Systematic reviews for the evidence of psychological interventions are reviewed in this article. The evidence for effectiveness is strongest for cognitive behavioural therapy with a focus on cognitive coping strategies and behavioural rehearsal. Most evidence is available for treatments of adult pain, although adolescent chronic pain treatments are also reviewed. It is clear that treatment benefit can be achieved with cognitive behavioural methods. It is possible to effect change in pain, mood, and disability, changes not achieved by chance or by exposure to any other treatment. However, the overall effect sizes of treatments for adults, across all trials, are modest. Reasons for the relatively modest treatment effects are discussed within the context of all treatments for chronic pain being disappointing when measured by the average. Suggestions for improving both trials and evidence summaries are made. Finally, consideration is given to what can be achieved by the pain specialist without access to specialist psychology resource.


Asunto(s)
Adaptación Psicológica , Dolor Crónico/psicología , Dolor Crónico/terapia , Terapia Cognitivo-Conductual/métodos , Manejo del Dolor/métodos , Humanos , Resultado del Tratamiento
5.
Occup Med (Lond) ; 63(7): 501-6, 2013 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-24027219

RESUMEN

BACKGROUND: The sickness certification and return to work (RTW) of people with chronic pain are important health and economic issues for employees, employers, taxpayers and the UK government. The 'fit note' and a national educational programme promoting RTW were introduced in 2010 to curb rising rates of sickness absence. AIMS: To investigate employers' and employees' experiences of managing RTW when someone has taken sick leave for chronic pain and to explore the perceived efficacy of the fit note. METHODS: A qualitative study, comprising semi-structured interviews with employers who had managed sick leave cases and employees who had experienced sick leave for chronic pain. Interviews were recorded, transcribed and the data analysed using constructivist grounded theory principles. RESULTS: Five themes were elicited. Firstly, frequent enquiry after health status was seen as intrusive by some employees but part of good practice by employers and acknowledging this difference was useful. Secondly, being able to trust employees due to their performance track record was helpful for employers when dealing with complex chronic pain conditions. Thirdly, feeling valued increased employees' motivation to RTW. Fourthly, guidelines about maintaining contact with absent employees were useful if used flexibly. Finally, both parties valued the fit note for its positive language, interrogative format and biomedical authority. CONCLUSIONS: The fit note was perceived to be helpful if used in combination with other strategies for managing sick leave and RTW for people with chronic pain. These strategies may be applicable to other fluctuating, long-term conditions with medically unexplained elements.


Asunto(s)
Actitud , Dolor Crónico , Empleo , Reinserción al Trabajo , Ausencia por Enfermedad , Adulto , Femenino , Guías como Asunto , Estado de Salud , Humanos , Entrevistas como Asunto , Masculino , Motivación , Privacidad , Investigación Cualitativa , Confianza , Reino Unido
6.
Int J Clin Pract Suppl ; (178): 47-50, 2013 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-23163549

RESUMEN

Proposed is a psychology of pain that focusses on normal psychological reactions to pain. A normal psychology of pain seeks to explain what normal people (those who would not meet any criteria for any psychological disorder) do when faced with pain. Herein, we focus on everyday pain defined as pain that is clinically unimportant that arises from normal everyday activity. Pain functions to interrupt current concerns and promote problem solving typically in the form of escape, pain management, or request for assistance. A model of analgesic problem solving is described. Focussing on pain as an interruption leads us to think about the purpose of analgesics in repairing attention and returning function. New endpoints for analgesic performance are offered. Similarly, a focus on pain as a motivation for analgesia demands that we understand how people self-medicate its relative success, and what influences patterns of self-medication. Finally, the problem of pain in children and adolescents, including self-medication in youth, is discussed. Although there is limited small-scale research on young people and their knowledge about analgesics, very little is known about their beliefs, attitudes to analgesics and their self-medication behaviour. Adolescents in most societies are left largely unguided. There is little child-specific communication about how to manage pain. Most children rely on parental knowledge, although increasingly the internet is becoming a source of advice for young people learning about analgesics.


Asunto(s)
Adaptación Psicológica , Analgésicos/uso terapéutico , Manejo del Dolor , Dolor , Automedicación/psicología , Actividades Cotidianas , Adaptación Psicológica/efectos de los fármacos , Adaptación Psicológica/fisiología , Adolescente , Adulto , Niño , Humanos , Modelos Psicológicos , Dolor/tratamiento farmacológico , Dolor/psicología , Manejo del Dolor/métodos , Manejo del Dolor/psicología , Educación del Paciente como Asunto , Conocimiento de la Medicación por el Paciente
7.
BMJ Mil Health ; 2022 Jul 22.
Artículo en Inglés | MEDLINE | ID: mdl-35868710

RESUMEN

INTRODUCTION: The military includes lower extremity amputees requiring arthroplasty; however, there is little literature on this population. The primary aim of this study was to report demographics and clinical factors in amputees who undergo total hip or knee arthroplasty (THA/TKA) in the Military Health System (MHS). Second, patient-reported outcome measures (PROMs) are reported. METHODS: The Military Data Repository was queried for patients with lower extremity amputations and TKA or THA between 1 October 2014 and 12 October 2020. The medical records were reviewed and patients were contacted to complete PROMs. Mean follow-up for TKA and THA was 5.5 and 2.5 years, respectively. RESULTS: Nineteen TKAs (76%) and eight THAs (28%) were performed in 25 patients. Mean age of TKA and THA patients at the time of arthroplasty was 57 years old. A majority of TKA (68%) and THA (57%) patients underwent amputations secondary to trauma. Nearly all TKAs were performed on the contralateral side to the amputation (95%), while half of THAs were performed on the ipsilateral side (50%). Two THAs (29%) were revised due to periprosthetic fractures, whereas six TKAs (32%) were revised or reoperated on due to infection. Ten TKA patients completed PROMs. The mean score on Knee Osteoarthritis Outcome Score for Joint Replacement (KOOS JR) was 41.8 and Patient-Reported Outcomes Measurement Information System Global-10 (PROMIS-10) was 41.6 (Global Physical Health) and 49.6 (Global Mental Health). CONCLUSIONS: Most TKAs were performed on the contralateral limb, suggesting increased demand on the joint. The most common indication for amputation and post-TKA complication was trauma and infection, respectively. KOOS JR may not accurately capture the outcomes of this population, or they simply do worse. However, PROMIS-10 scores were similar to the non-amputee population, suggesting that the PROMIS-10 may be more useful than the KOOS JR.

8.
Int J Obes (Lond) ; 35(5): 728-35, 2011 May.
Artículo en Inglés | MEDLINE | ID: mdl-20820169

RESUMEN

OBJECTIVE: This study examined the independent effect of a patient's weight on medical students' attitudes, beliefs and interpersonal behavior toward the patient, in addition to the clinical recommendations they make for her care. DESIGN: A total of 76 clinical-level medical students were randomly assigned to interact with a digital, virtual female patient who was visibly either obese or non-obese. METHODS: Interactions with the patient took place in an immersive virtual (virtual reality) clinical environment that allowed standardization of all patient behaviors and characteristics except for weight. Visual contact behavior was automatically recorded during the interaction. Afterward, participants filled out a battery of self-report questionnaires. RESULTS: Analyses revealed more negative stereotyping, less anticipated patient adherence, worse perceived health, more responsibility attributed for potentially weight-related presenting complaints and less visual contact directed toward the obese version of a virtual patient than the non-obese version of the patient. In contrast, there was no clear evidence of bias in clinical recommendations made for the patient's care. CONCLUSION: Biases in attitudes, beliefs and interpersonal behavior have important implications because they can influence the tone of clinical encounters and rapport in the patient-provider relationship, which can have important downstream consequences. Gaining a clear understanding of the nature and source of weight bias in the clinical encounter is an important first step toward the development of strategies to address it.


Asunto(s)
Actitud del Personal de Salud , Simulación por Computador , Obesidad/psicología , Estudiantes de Medicina/psicología , Análisis de Varianza , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Relaciones Interpersonales , Masculino , Obesidad/terapia , Estereotipo , Encuestas y Cuestionarios
9.
Eur J Pain ; 21(10): 1668-1677, 2017 11.
Artículo en Inglés | MEDLINE | ID: mdl-28695655

RESUMEN

BACKGROUND: Pain can be detected through nonverbal cues, including facial expressions, vocalisations, and body posture. While there are sex differences in how emotional expressions are recognized, these differences have not always been found for pain. One reason for this inconsistency may be methodological, as pain studies tend not to be designed to investigate individual differences in expression recognition. Also, few studies consider sex differences outside facial expression. METHODS: This study applied an image degradation method used to examine individual differences in emotion recognition, to investigate sex differences in the decoding of pain body postures. Forty participants (20 male) were presented with a series of body posture images depicting pain at differing levels of image degradation. Happiness, anger and sadness expressions were also included for comparison. RESULTS: Results showed significant effects of image degradation, affect type, and actor sex. Females were rated as presenting more intense pain than males; this pattern was also found for fear, but not anger or happiness. The accuracy of pain intensity judgements was reduced as image clarity decreased. Male actors depicting pain were recognized with greater accuracy than female actors. Interestingly, similar patterns were found for anger and fear expressions. CONCLUSIONS: We conclude that sex has a significant influence on pain decoding under certain conditions, and while there are similarities with the way pain and core emotions are decoded, this may depend on the type of emotion presented. This also suggests that sex-related effects in the recognition of pain expressions may include body postural cues. SIGNIFICANCE: Observer's judgements of pain displayed through body postures are driven by the sex of the person in pain.


Asunto(s)
Dolor/psicología , Postura , Factores Sexuales , Adulto , Señales (Psicología) , Emociones , Expresión Facial , Femenino , Humanos , Masculino , Adulto Joven
10.
Pain ; 158(3): 471-478, 2017 03.
Artículo en Inglés | MEDLINE | ID: mdl-28067692

RESUMEN

Adult patients with chronic pain are consistently shown to interpret ambiguous health and bodily information in a pain-related and threatening way. This interpretation bias may play a role in the development and maintenance of pain and disability. However, no studies have yet investigated the role of interpretation bias in adolescent patients with pain, despite that pain often first becomes chronic in youth. We administered the Adolescent Interpretations of Bodily Threat (AIBT) task to adolescents with chronic pain (N = 66) and adolescents without chronic pain (N = 74). Adolescents were 10 to 18 years old and completed the study procedures either at the clinic (patient group) or at school (control group). We found that adolescents with chronic pain were less likely to endorse benign interpretations of ambiguous pain and bodily threat information than adolescents without chronic pain, particularly when reporting on the strength of belief in those interpretations being true. These differences between patients and controls were not evident for ambiguous social situations, and they could not be explained by differences in anxious or depressive symptoms. Furthermore, this interpretation pattern was associated with increased levels of disability among adolescent patients, even after controlling for severity of chronic pain and pain catastrophizing. The current findings extend our understanding of the role and nature of cognition in adolescent pain, and provide justification for using the AIBT task in longitudinal and training studies to further investigate causal associations between interpretation bias and chronic pain.


Asunto(s)
Sesgo , Catastrofización/psicología , Dolor Crónico/psicología , Trastornos del Humor/etiología , Sensación/fisiología , Adolescente , Análisis de Varianza , Catastrofización/etiología , Niño , Dolor Crónico/complicaciones , Evaluación de la Discapacidad , Personas con Discapacidad/psicología , Femenino , Humanos , Masculino , Trastornos del Humor/psicología , Dimensión del Dolor , Escalas de Valoración Psiquiátrica , Estudios Retrospectivos
11.
Eur J Pain ; 21(2): 250-263, 2017 02.
Artículo en Inglés | MEDLINE | ID: mdl-27463940

RESUMEN

BACKGROUND: Pain is common and can be debilitating in childhood. Theoretical models propose that attention to pain plays a key role in pain outcomes, however, very little research has investigated this in youth. This study examined how anxiety-related variables and attention control interacted to predict children's attention to pain cues using eye-tracking methodology, and their pain tolerance on the cold pressor test (CPT). METHODS: Children aged 8-17 years had their eye-gaze tracked whilst they viewed photographs of other children displaying painful facial expressions during the CPT, before completing the CPT themselves. Children also completed self-report measures of anxiety and attention control. RESULTS: Findings indicated that anxiety and attention control did not impact children's initial fixations on pain or neutral faces, but did impact how long they dwelled on pain versus neutral faces. For children reporting low levels of attention control, higher anxiety was associated with less dwell time on pain faces as opposed to neutral faces, and the opposite pattern was observed for children with high attention control. Anxiety and attention control also interacted to predict pain outcomes. For children with low attention control, increasing anxiety was associated with anticipating more pain and tolerating pain for less time. CONCLUSIONS: This is the first study to examine children's attention to pain cues using eye-tracking technology in the context of a salient painful experience. Data suggest that attention control is an important moderator of anxiety on multiple outcomes relevant to young people's pain experiences. SIGNIFICANCE: This study uses eye tracking to study attention to pain cues in children. Attention control is an important moderator of anxiety on attention bias to pain and tolerance of cold pressor pain in youth.


Asunto(s)
Ansiedad/psicología , Atención/fisiología , Percepción del Dolor/fisiología , Umbral del Dolor/psicología , Dolor/psicología , Adolescente , Niño , Expresión Facial , Femenino , Humanos , Masculino , Dimensión del Dolor/métodos , Autoinforme
12.
Eur J Pain ; 19(6): 842-51, 2015 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-25380528

RESUMEN

BACKGROUND: Anxiety, in particular pain-related anxiety, plays an important role in explaining the severity of pain complaints and pain-related disability in both adults and children with chronic pain. The fear-avoidance model (FAM) describes how pain-related anxiety plays a critical role in the maintenance of pain-avoidance behaviour, which in turn influences pain-related disability. However, the FAM does not take into account broader aspects of adolescence, such as social functioning, which could be negatively impacted by anxiety. In addition, most studies examining the role of anxiety in pain have used small convenience or clinical samples. By using a large UK epidemiological database, this study investigated the associations between pain-related anxiety, disability and judgements of social impairment. METHODS: Participants (n = 856) with recurrent pain were selected from a larger epidemiological study (Avon Longitudinal Study of Parents and Children) of adolescents attending a research clinic at the age of 17 (n = 5170). Adolescents completed a self-report questionnaire on pain-related anxiety, disability and perceived social impairment. RESULTS: High levels of pain-related anxiety were associated with more disability. In girls, higher levels of pain-related anxiety were also related to the self-perception of greater impairment in social functioning compared with their peers. CONCLUSIONS: Pain-related anxiety was associated with greater pain-related disability and impaired social functioning. Social functioning should be explored as an integral part of fear-avoidance models of adolescent chronic pain.


Asunto(s)
Trastornos de Ansiedad/psicología , Ansiedad/psicología , Reacción de Prevención/fisiología , Dolor Crónico/psicología , Miedo/psicología , Autoimagen , Adolescente , Trastornos de Ansiedad/complicaciones , Dolor Crónico/complicaciones , Evaluación de la Discapacidad , Femenino , Humanos , Estudios Longitudinales , Masculino , Dimensión del Dolor/métodos , Encuestas y Cuestionarios
13.
Pain ; 80(1-2): 1-13, 1999 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-10204712

RESUMEN

A computer and a hand search of the literature recovered 33 papers from which 25 trials suitable for meta-analysis were identified. We compared the effectiveness of cognitive-behavioural treatments with the waiting list control and alternative treatment control conditions. There was a great diversity of measurements which we grouped into domains representing major facets of pain. Effect sizes, corrected for measurement unreliability, were estimated for each domain. When compared with the waiting list control conditions cognitive-behavioural treatments were associated with significant effect sizes on all domains of measurement (median effect size across domains = 0.5). Comparison with alternative active treatments revealed that cognitive-behavioural treatments produced significantly greater changes for the domains of pain experience, cognitive coping and appraisal (positive coping measures), and reduced behavioural expression of pain. Differences on the following domains were not significant; mood/affect (depression and other, non-depression, measures), cognitive coping and appraisal (negative, e.g. catastrophization), and social role functioning. We conclude that active psychological treatments based on the principle of cognitive behavioural therapy are effective. We discuss the results with reference to the complexity and quality of the trials.


Asunto(s)
Terapia Conductista , Terapia Cognitivo-Conductual , Manejo del Dolor , Adulto , Enfermedad Crónica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dolor/etiología , Ensayos Clínicos Controlados Aleatorios como Asunto , Proyectos de Investigación , Tamaño de la Muestra
14.
Pain ; 72(1-2): 209-15, 1997 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-9272805

RESUMEN

Empirical methods are used to explore the relationship between chronic pain, somatic awareness and attention. Using a primary task paradigm, 46 chronic pain patients performed an attentionally demanding task. Patients were classified according to self reported pain intensity and the extent of their reporting of the perception of bodily sensations (somatic awareness). Results showed that, as predicted, disruption of attentional performance was most pronounced in those who reported high pain intensity and high somatic awareness. Further analysis revealed that these patients also reported high negative affect. These findings are discussed in terms of their theoretical implications for the concept of hypervigilance and their clinical implications for chronic pain control.


Asunto(s)
Atención/fisiología , Concienciación/fisiología , Dolor/psicología , Sensación/fisiología , Adulto , Anciano , Enfermedad Crónica , Femenino , Humanos , Masculino , Persona de Mediana Edad
15.
Pain ; 70(2-3): 149-54, 1997 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-9150288

RESUMEN

Pain interrupts, distracts and is difficult to disengage from. In this experiment the attentional interference during pain is studied with a primary task paradigm. We were interested in the strength of attentional interference with repeated presentations of pain. Healthy volunteers (n = 24) performed a tone discrimination task in the presence of two types of distractors (an electrical pain stimulus and a control stimulus) which they were instructed to ignore. On some trials, tone probes were presented immediately (250 ms) after distractor onset, further on (750 ms) during the distractor, and immediately (250 ms) after distractor offset. Habituation of the task interference during the early processing of both the pain and the control stimulus was observed. It was also found that the attentional interference during pain did not completely disappear with repeated presentations. Finally, results clearly showed a more prolonged processing time of the tones during pain trials than during control trials. These results are discussed in terms of cognitive theories of habituation.


Asunto(s)
Habituación Psicofisiológica , Dolor/psicología , Análisis y Desempeño de Tareas , Estimulación Acústica , Adolescente , Adulto , Atención , Conducta , Estimulación Eléctrica , Femenino , Humanos , Masculino , Autoimagen
16.
Pain ; 75(2-3): 187-98, 1998 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-9583754

RESUMEN

Styles of catastrophic thinking about pain have been related to an inability to divert attention away from pain. We investigated whether pain catastrophizers displayed high attentional interference during a threatening low-intensity electrocutaneous stimulus (ES). In Experiment 1, 44 undergraduates performed a tone discrimination task whilst experiencing several times an ES on the left or right arms. Tones were also presented 250 ms and 750 ms after ES onset. Participants were threatened that a high-intensity painful stimulus would occur at one site. As predicted, pain catastrophizers displayed pronounced task interference immediately after threat stimulus onset. In Experiment 2, threat was induced in 36 undergraduates by informing them that an ES excites pain fibres. Again, catastrophizers had marked interference immediately after onset. The results are discussed in terms of how catastrophizing amplifies somatosensory information and primes fear mechanisms.


Asunto(s)
Ansiedad/psicología , Atención , Pensamiento , Adolescente , Adulto , Conducta , Femenino , Humanos , Masculino , Autoevaluación (Psicología)
17.
Psychol Bull ; 125(3): 356-66, 1999 May.
Artículo en Inglés | MEDLINE | ID: mdl-10349356

RESUMEN

Pain interrupts and demands attention. The authors review evidence for how and why this interruption of attention is achieved. The interruptive function of pain depends on the relationship between pain-related characteristics (e.g., the threat value of pain) and the characteristics of the environmental demands (e.g., emotional arousal). A model of the interruptive function of pain is developed that holds that pain is selected for action from within complex affective and motivational environments to urge escape. The implications of this model for research and therapy are outlined with an emphasis on the redefinition of chronic pain as chronic interruption.


Asunto(s)
Afecto , Atención/fisiología , Cognición/fisiología , Dolor/psicología , Enfermedad Crónica , Humanos
18.
J Appl Physiol (1985) ; 70(4): 1483-9, 1991 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-1711521

RESUMEN

The purpose of this study was to examine whether antioxidants attenuate endotoxin-induced microvascular hyper-permeability for macromolecules in the hamster cheek pouch. Twenty-two adult male Syrian hamsters were anesthetized, and a removable plastic chamber was placed in the cheek pouch to observe and collect suffusate from the microvasculature. Fluorescent-labeled dextran (FITC-D; mol wt 150,000) was injected intravenously, and changes in the number of microvascular leaky sites and microvascular clearance of FITC-D were measured in five groups: saline control (group 1, n = 4), endotoxin (0.1 mg/ml) suffusion for 120 min (group 2, n = 6), endotoxin plus dimethyl sulfoxide (1.0 g/kg iv; group 3, n = 4), endotoxin plus allopurinol (30 mg/kg ip; group 4, n = 4), and endotoxin plus dimethyl sulfoxide and allopurinol (group 5, n = 4). The number of leaky sites and the FITC-D clearance were significantly higher in group 2 [45 +/- 18 (SD) sites/cm2 and 20 +/- 6 X 10(-6) ml/min, respectively; P less than 0.01] than in group 1 (7 +/- 6 sites/cm2 and 7 +/- 5 X 10(-6) ml/min), group 3 (9 +/- 5 sites/cm2 and 8 +/- 2 X 10(-6) ml/min), group 4 (11 +/- 7 sites/cm2 and 9 +/- 4 X 10(-6) ml/min), and group 5 (11 +/- 6 sites/cm2 and 7 +/- 1 x 10(-6) ml/min). The leaky sites appeared predominantly in postcapillary venules. There was a positive and significant correlation between the number of leaky sites and FITC-D clearance.(ABSTRACT TRUNCATED AT 250 WORDS)


Asunto(s)
Antioxidantes/farmacología , Permeabilidad Capilar/efectos de los fármacos , Endotoxinas/toxicidad , Fluoresceína-5-Isotiocianato/análogos & derivados , Alopurinol/farmacología , Animales , Cricetinae , Dextranos , Dimetilsulfóxido/farmacología , Endotoxinas/antagonistas & inhibidores , Fluoresceínas , Radicales Libres , Masculino , Mesocricetus , Oxígeno/metabolismo
19.
Health Technol Assess ; 1(6): i-iv, 1-135, 1997.
Artículo en Inglés | MEDLINE | ID: mdl-9483161

RESUMEN

AIM OF REPORT. This report reviews the evidence about the effectiveness of treatments for chronic pain. While treatment of chronic pain is usually seen as an integrated service, this report concentrates on the individual interventions that constitute the service. HOW THE RESEARCH WAS CONDUCTED. Searches of databases and journals identified over 15,000 randomised studies with pain as an outcome, and many more which were not randomised. Over 150 systematic reviews relevant to chronic pain treatment were identified and their quality assessed using a simple scoring system. Systematic reviews conducted for this report were based mainly on randomised trials. The number needed to treat (NNT) was chosen as the output for the report. NNTs of 2-4 indicate effective treatments. Because NNT is treatment-specific it overcomes problems associated with highly variable placebo or control event rates in pain trials. Such variability is predominantly due to the limited numbers of patients in the clinical trials. Dichotomous outcome measures are important in synthesising information from many studies, and in deriving NNTs. Methods have been developed which allow mean information on pain relief and intensity to be converted reliably into the simple dichotomous outcome of at least 50% pain relief. RESEARCH FINDINGS. PHYSICAL INTERVENTIONS. Transcutaneous electrical nerve stimulation (TENS) has been shown not to be effective in postoperative and labour pain. In chronic pain, there is evidence that TENS effectiveness increases slowly, and that large doses need to be used. There is lack of evidence for the effectiveness of TENS in chronic pain. There is a lack of evidence for the effectiveness of relaxation. Intravenous systemic regional blockade with guanethidine has been shown to be without effect. Epidural corticosteroids are effective in the short term for back pain and sciatica. Injections of corticosteroids in or around shoulder joints for shoulder pain have been shown not to be effective. There is a lack of evidence supporting spinal cord stimulators. Case series are of poor quality and do not provide evidence of effectiveness, although at least 50% pain relief at 5 years is reported in over 50% of patients. PHARMACOLOGICAL INTERVENTIONS. Minor analgesics are important in chronic pain. NNTs were calculated for analgesics given orally for moderate or severe acute postoperative pain. The NNTs found ranged from 17 (poor) for codeine, 60 mg, to 2.5 (good) for ibuprofen, 400 mg. Anticonvulsant and antidepressant drugs are prescribed for neuropathic pains like diabetic neuropathy. NNTs are of the order of 2.5, showing them to be effective treatments. However, there are too few studies with too few patients to determine which is the best drug. Minor adverse events are common, and major adverse events occur in about 1 in 20 patients. There are no studies comparing antidepressants and anticonvulsants directly. Systemic local anaesthetic-type drugs have been shown to be effective in nerve injury pain but there is little or no evidence to support their use in migraine or cancer-related pain. Topical NSAIDs (for example, gels, creams) are effective in rheumatological conditions with an overall NNT of 3. There are too few studies to determine which is the best agent. Topical NSAIDs have few adverse events; most importantly they are without the major gastrointestinal adverse events found with oral NSAIDs, which might make them an important choice for some patients with peripheral arthritis. (ABSTRACT TRUNCATED)


Asunto(s)
Atención Ambulatoria/normas , Clínicas de Dolor/normas , Manejo del Dolor , Calidad de la Atención de Salud , Atención Ambulatoria/economía , Atención Ambulatoria/métodos , Analgésicos/uso terapéutico , Anestésicos Locales/uso terapéutico , Antiinflamatorios no Esteroideos/uso terapéutico , Anticonvulsivantes/uso terapéutico , Antidepresivos/uso terapéutico , Enfermedad Crónica , Interpretación Estadística de Datos , Investigación sobre Servicios de Salud , Humanos , Dolor/psicología , Dimensión del Dolor/métodos , Dimensión del Dolor/normas , Ensayos Clínicos Controlados Aleatorios como Asunto/normas , Relajación , Estimulación Eléctrica Transcutánea del Nervio , Reino Unido
20.
Eur J Pain ; 5(3): 309-18, 2001.
Artículo en Inglés | MEDLINE | ID: mdl-11558986

RESUMEN

Patients with chronic pain often report negative and aversive rumination about pain and its consequences. Little is known about how and why patients with chronic pain worry. This study provides a description of worrying by chronic pain patients. Eighteen female and 16 male chronic pain patients reported, over a 7-day period, their experience of pain-related and non-pain-related worry. Results indicated that, in comparison with non-pain related worry, worry about chronic pain is experienced as more difficult to dismiss, more distracting, more attention grabbing, more intrusive, more distressing and less pleasant. Further analyses suggest that these characteristics of worry about chronic pain do not arise from a general disposition to worry or from a general disposition to anxiety. Worry is, however, related to awareness of somatic sensations. These results are discussed within an attentional model in which worry functions to maintain vigilance to threat.


Asunto(s)
Ansiedad/psicología , Dimensión del Dolor/psicología , Dolor/psicología , Adulto , Anciano , Atención/fisiología , Enfermedad Crónica , Femenino , Humanos , Masculino , Escala de Ansiedad Manifiesta , Persona de Mediana Edad , Dolor/fisiopatología , Encuestas y Cuestionarios
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