Detalles de la búsqueda
1.
Glioblastomas located in proximity to the subventricular zone (SVZ) exhibited enrichment of gene expression profiles associated with the cancer stem cell state.
J Neurooncol;
148(3): 455-462, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32556864
2.
The Thermodynamics of Ligand Binding to the Aminoglycoside O-Nucleotidyltransferase(4') and Variants Yields Clues about Thermophilic Properties.
Biochemistry;
58(12): 1579-1586, 2019 03 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30793594
3.
Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew Chem Int Ed Engl;
58(45): 16260-16266, 2019 11 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31515870
4.
Aminoglycoside binding and catalysis specificity of aminoglycoside 2â³-phosphotransferase IVa: A thermodynamic, structural and kinetic study.
Biochim Biophys Acta;
1860(4): 802-13, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26802312
5.
Thermodynamics of an aminoglycoside modifying enzyme with low substrate promiscuity: The aminoglycoside N3 acetyltransferase-VIa.
Proteins;
85(7): 1258-1265, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28316100
6.
Efficacy of metronomic vinorelbine in elderly patients with advanced non-small-cell lung cancer and poor performance status.
Curr Oncol;
24(3): e199-e204, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28680287
7.
Correction to Thermodynamic Characterization of a Thermostable Antibiotic Resistance Enzyme, the Aminoglycoside Nucleotidyltransferase (4').
Biochemistry;
54(32): 5120, 2015 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26252172
8.
Solvent reorganization plays a temperature-dependent role in antibiotic selection by a thermostable aminoglycoside nucleotidyltransferase-4'.
Biochemistry;
53(34): 5544-50, 2014 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25093604
9.
Protein dynamics are influenced by the order of ligand binding to an antibiotic resistance enzyme.
Biochemistry;
53(1): 30-8, 2014 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24320996
10.
Thermodynamic characterization of a thermostable antibiotic resistance enzyme, the aminoglycoside nucleotidyltransferase (4').
Biochemistry;
51(45): 9147-55, 2012 Nov 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23066871
11.
A strategy based on protein-protein interface motifs may help in identifying drug off-targets.
J Chem Inf Model;
52(8): 2273-86, 2012 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22817115
12.
Antibiotic selection by the promiscuous aminoglycoside acetyltransferase-(3)-IIIb is thermodynamically achieved through the control of solvent rearrangement.
Biochemistry;
50(43): 9309-17, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21958034
13.
Coenzyme A binding to the aminoglycoside acetyltransferase (3)-IIIb increases conformational sampling of antibiotic binding site.
Biochemistry;
50(48): 10559-65, 2011 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22026726
14.
The access rate to diagnosis and treatment modalities in breast cancer patients in Turkey; multicenter observational study.
J BUON;
16(4): 664-71, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22331719
15.
Thermodynamics and kinetics of association of antibiotics with the aminoglycoside acetyltransferase (3)-IIIb, a resistance-causing enzyme.
Biochemistry;
49(19): 4027-35, 2010 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20387903
16.
Interactions of coenzyme A with the aminoglycoside acetyltransferase (3)-IIIb and thermodynamics of a ternary system.
Biochemistry;
49(19): 4036-42, 2010 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20387904
17.
"Catch and Release": A Variation of the Archetypal Nucleotidyl Transfer Reaction.
ACS Catal;
10(6): 3548-3555, 2020 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38250052
18.
NMR detected hydrogen-deuterium exchange reveals differential dynamics of antibiotic- and nucleotide-bound aminoglycoside phosphotransferase 3'-IIIa.
J Am Chem Soc;
131(24): 8587-94, 2009 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-19463004
19.
Studies of enzymes that cause resistance to aminoglycosides antibiotics.
Methods Mol Med;
142: 261-71, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18437320
20.
A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad.
Sci Adv;
4(4): eaas8667, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29632894