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1.

ATXN3 controls DNA replication and transcription by regulating chromatin structure.

Hernández-Carralero, Esperanza; Cabrera, Elisa; Rodríguez-Torres, Gara; Hernández-Reyes, Yeray; Singh, Abhay N; Santa-María, Cristina; Fernández-Justel, José Miguel; Janssens, Roel C; Marteijn, Jurgen A; Evert, Bernd O; Mailand, Niels; Gómez, María; Ramadan, Kristijan; Smits, Veronique A J; Freire, Raimundo.

Nucleic Acids Res; 51(11): 5396-5413, 2023 06 23.

Artículo en Inglés | MEDLINE | ID: mdl-36971114

2.

Spinocerebellar Ataxia Type 3 Pathophysiology-Implications for Translational Research and Clinical Studies.

Stahl, Fabian; Evert, Bernd O; Han, Xinyu; Breuer, Peter; Wüllner, Ullrich.

Int J Mol Sci; 25(7)2024 Apr 03.

Artículo en Inglés | MEDLINE | ID: mdl-38612794

3.

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.

Koch, Philipp; Breuer, Peter; Peitz, Michael; Jungverdorben, Johannes; Kesavan, Jaideep; Poppe, Daniel; Doerr, Jonas; Ladewig, Julia; Mertens, Jerome; Tüting, Thomas; Hoffmann, Per; Klockgether, Thomas; Evert, Bernd O; Wüllner, Ullrich; Brüstle, Oliver.

Nature; 480(7378): 543-6, 2011 Nov 23.

Artículo en Inglés | MEDLINE | ID: mdl-22113611

4.

The Alpha-Synuclein Gene (SNCA) is a Genomic Target of Methyl-CpG Binding Protein 2 (MeCP2)-Implications for Parkinson's Disease and Rett Syndrome.

Schmitt, Ina; Evert, Bernd O; Sharma, Amit; Khazneh, Hassan; Murgatroyd, Chris; Wüllner, Ullrich.

Mol Neurobiol; 2024 Mar 02.

Artículo en Inglés | MEDLINE | ID: mdl-38429622

5.

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

Araujo, Julieta; Breuer, Peter; Dieringer, Susanne; Krauss, Sybille; Dorn, Stephanie; Zimmermann, Katrin; Pfeifer, Alexander; Klockgether, Thomas; Wuellner, Ullrich; Evert, Bernd O.

Hum Mol Genet; 20(15): 2928-41, 2011 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-21536589

6.

Downregulation of MGMT expression by targeted editing of DNA methylation enhances temozolomide sensitivity in glioblastoma.

Han, Xinyu; Abdallah, Mohammed O E; Breuer, Peter; Stahl, Fabian; Bakhit, Yousuf; Potthoff, Anna-Laura; Pregler, Barbara E F; Schneider, Matthias; Waha, Andreas; Wüllner, Ullrich; Evert, Bernd O.

Neoplasia; 44: 100929, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37634280

7.

Nuclear aggregation of polyglutamine-expanded ataxin-3: fragments escape the cytoplasmic quality control.

Breuer, Peter; Haacke, Annette; Evert, Bernd O; Wüllner, Ullrich.

J Biol Chem; 285(9): 6532-7, 2010 Feb 26.

Artículo en Inglés | MEDLINE | ID: mdl-20064935

8.

CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.

Mueller, Thorsten; Breuer, Peter; Schmitt, Ina; Walter, Jochen; Evert, Bernd O; Wüllner, Ullrich.

Hum Mol Genet; 18(17): 3334-43, 2009 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-19542537

9.

Activators of alpha synuclein expression identified by reporter cell line-based high throughput drug screen.

Stahl, Fabian; Denner, Philip; Piston, Dominik; Evert, Bernd O; de Boni, Laura; Schmitt, Ina; Breuer, Peter; Wüllner, Ullrich.

Sci Rep; 11(1): 19857, 2021 10 06.

Artículo en Inglés | MEDLINE | ID: mdl-34615900

10.

Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status.

Schneider, Matthias; Potthoff, Anna-Laura; Evert, Bernd O; Dicks, Marius; Ehrentraut, Denise; Dolf, Andreas; Schmidt, Elena N C; Schäfer, Niklas; Borger, Valeri; Pietsch, Torsten; Westhoff, Mike-Andrew; Güresir, Erdem; Waha, Andreas; Vatter, Hartmut; Heiland, Dieter H; Schuss, Patrick; Herrlinger, Ulrich.

Pharmaceuticals (Basel); 14(3)2021 Feb 27.

Artículo en Inglés | MEDLINE | ID: mdl-33673490

11.

Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma.

Schneider, Matthias; Vollmer, Lea; Potthoff, Anna-Laura; Ravi, Vidhya M; Evert, Bernd O; Rahman, Mohummad A; Sarowar, Shahin; Kueckelhaus, Jan; Will, Paulina; Zurhorst, David; Joseph, Kevin; Maier, Julian P; Neidert, Nicolas; d'Errico, Paolo; Meyer-Luehmann, Melanie; Hofmann, Ulrich G; Dolf, Andreas; Salomoni, Paolo; Güresir, Erdem; Enger, Per Ø; Chekenya, Martha; Pietsch, Torsten; Schuss, Patrick; Schnell, Oliver; Westhoff, Mike-Andrew; Beck, Jürgen; Vatter, Hartmut; Waha, Andreas; Herrlinger, Ulrich; Heiland, Dieter H.

Neuro Oncol; 23(11): 1885-1897, 2021 11 02.

Artículo en Inglés | MEDLINE | ID: mdl-33864086

12.

The Role of MicroRNAs in Spinocerebellar Ataxia Type 3.

Krauss, Sybille; Evert, Bernd O.

J Mol Biol; 431(9): 1729-1742, 2019 04 19.

Artículo en Inglés | MEDLINE | ID: mdl-30664869

13.

Upregulation of miR-25 and miR-181 Family Members Correlates with Reduced Expression of ATXN3 in Lymphocytes from SCA3 Patients.

Krauss, Sybille; Nalavade, Rohit; Weber, Stephanie; Carter, Katlynn; Evert, Bernd O.

Microrna; 8(1): 76-85, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30147021

14.

Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide.

Potthoff, Anna-Laura; Heiland, Dieter Henrik; Evert, Bernd O; Almeida, Filipe Rodrigues; Behringer, Simon P; Dolf, Andreas; Güresir, Ági; Güresir, Erdem; Joseph, Kevin; Pietsch, Torsten; Schuss, Patrick; Herrlinger, Ulrich; Westhoff, Mike-Andrew; Vatter, Hartmut; Waha, Andreas; Schneider, Matthias.

Cancers (Basel); 11(6)2019 Jun 20.

Artículo en Inglés | MEDLINE | ID: mdl-31226836

15.

Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability.

Pieper, Heike C; Evert, Bernd O; Kaut, Oliver; Riederer, Peter F; Waha, Andreas; Wüllner, Ullrich.

Neurobiol Dis; 32(3): 521-7, 2008 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-18930140

16.

Pathological consequences of VCP mutations on human striated muscle.

Hübbers, Christian U; Clemen, Christoph S; Kesper, Kristina; Böddrich, Annett; Hofmann, Andreas; Kämäräinen, Outi; Tolksdorf, Karen; Stumpf, Maria; Reichelt, Julia; Roth, Udo; Krause, Sabine; Watts, Giles; Kimonis, Virginia; Wattjes, Mike P; Reimann, Jens; Thal, Dietmar R; Biermann, Katharina; Evert, Bernd O; Lochmüller, Hanns; Wanker, Erich E; Schoser, Benedikt G H; Noegel, Angelika A; Schröder, Rolf.

Brain; 130(Pt 2): 381-93, 2007 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-16984901

17.

Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3.

Evert, Bernd O; Nalavade, Rohit; Jungverdorben, Johannes; Matthes, Frank; Weber, Stephanie; Rajput, Ashish; Bonn, Stefan; Brüstle, Oliver; Peitz, Michael; Krauß, Sybille.

PLoS One; 13(8): e0201794, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30086154

18.

Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation.

Evert, Bernd O; Araujo, Julieta; Vieira-Saecker, Ana M; de Vos, Rob A I; Harendza, Sigrid; Klockgether, Thomas; Wüllner, Ullrich.

J Neurosci; 26(44): 11474-86, 2006 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-17079677

19.

Reciprocal Regulation between Bifunctional miR-9/9(∗) and its Transcriptional Modulator Notch in Human Neural Stem Cell Self-Renewal and Differentiation.

Roese-Koerner, Beate; Stappert, Laura; Berger, Thomas; Braun, Nils Christian; Veltel, Monika; Jungverdorben, Johannes; Evert, Bernd O; Peitz, Michael; Borghese, Lodovica; Brüstle, Oliver.

Stem Cell Reports; 7(2): 207-19, 2016 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-27426040

20.

Structural modeling of ataxin-3 reveals distant homology to adaptins.

Albrecht, Mario; Hoffmann, Daniel; Evert, Bernd O; Schmitt, Ina; Wüllner, Ullrich; Lengauer, Thomas.

Proteins; 50(2): 355-70, 2003 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-12486728

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