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1.

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.

Cassier, Philippe A; Navaridas, Raul; Bellina, Melanie; Rama, Nicolas; Ducarouge, Benjamin; Hernandez-Vargas, Hector; Delord, Jean-Pierre; Lengrand, Justine; Paradisi, Andrea; Fattet, Laurent; Garin, Gwenaële; Gheit, Hanane; Dalban, Cecile; Pastushenko, Ievgenia; Neves, David; Jelin, Remy; Gadot, Nicolas; Braissand, Nicolas; Léon, Sophie; Degletagne, Cyril; Matias-Guiu, Xavier; Devouassoux-Shisheboran, Mojgan; Mery-Lamarche, Eliane; Allard, Justine; Zindy, Egor; Decaestecker, Christine; Salmon, Isabelle; Perol, David; Dolcet, Xavi; Ray-Coquard, Isabelle; Blanpain, Cédric; Bernet, Agnès; Mehlen, Patrick.

Nature; 620(7973): 409-416, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37532934

2.

Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing.

Aubol, Brandon E; Wu, Guowei; Keshwani, Malik M; Movassat, Maliheh; Fattet, Laurent; Hertel, Klemens J; Fu, Xiang-Dong; Adams, Joseph A.

Mol Cell; 63(2): 218-228, 2016 07 21.

Artículo en Inglés | MEDLINE | ID: mdl-27397683

3.

CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly.

Aubol, Brandon E; Wozniak, Jacob M; Fattet, Laurent; Gonzalez, David J; Adams, Joseph A.

Proc Natl Acad Sci U S A; 118(14)2021 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-33811140

4.

Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling.

Ondeck, Matthew G; Kumar, Aditya; Placone, Jesse K; Plunkett, Christopher M; Matte, Bibiana F; Wong, Kirsten C; Fattet, Laurent; Yang, Jing; Engler, Adam J.

Proc Natl Acad Sci U S A; 116(9): 3502-3507, 2019 02 26.

Artículo en Inglés | MEDLINE | ID: mdl-30755531

5.

Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate.

George, Athira; Aubol, Brandon E; Fattet, Laurent; Adams, Joseph A.

J Biol Chem; 294(24): 9631-9641, 2019 06 14.

Artículo en Inglés | MEDLINE | ID: mdl-31064840

6.

Molecular interactions connecting the function of the serine-arginine-rich protein SRSF1 to protein phosphatase 1.

Aubol, Brandon E; Serrano, Pedro; Fattet, Laurent; Wüthrich, Kurt; Adams, Joseph A.

J Biol Chem; 293(43): 16751-16760, 2018 10 26.

Artículo en Inglés | MEDLINE | ID: mdl-30185622

7.

Mobilization of a splicing factor through a nuclear kinase-kinase complex.

Aubol, Brandon E; Keshwani, Malik M; Fattet, Laurent; Adams, Joseph A.

Biochem J; 475(3): 677-690, 2018 02 14.

Artículo en Inglés | MEDLINE | ID: mdl-29335301

8.

Netrin-4 regulates stiffness and metastasis.

Mehlen, Patrick; Fattet, Laurent.

Nat Mater; 20(6): 722-723, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-34045700

9.

Tif1Î³ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition.

Hesling, Cédric; Lopez, Jonathan; Fattet, Laurent; Gonzalo, Philippe; Treilleux, Isabelle; Blanchard, Daphné; Losson, Régine; Goffin, Vincent; Pigat, Natascha; Puisieux, Alain; Mikaelian, Ivan; Gillet, Germain; Rimokh, Ruth.

Development; 140(1): 167-75, 2013 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-23154409

10.

Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.

Keshwani, Malik M; Aubol, Brandon E; Fattet, Laurent; Ma, Chen-Ting; Qiu, Jinsong; Jennings, Patricia A; Fu, Xiang-Dong; Adams, Joseph A.

Biochem J; 466(2): 311-22, 2015 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-25529026

11.

Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates.

Keshwani, Malik M; Hailey, Kendra L; Aubol, Brandon E; Fattet, Laurent; McGlone, Maria L; Jennings, Patricia A; Adams, Joseph A.

Biochem J; 472(3): 329-38, 2015 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-26443864

12.

TIF1Î³ requires sumoylation to exert its repressive activity on TGFß signaling.

Fattet, Laurent; Ay, Anne-Sophie; Bonneau, Benjamin; Jallades, Laurent; Mikaelian, Ivan; Treilleux, Isabelle; Gillet, Germain; Hesling, Cédric; Rimokh, Ruth.

J Cell Sci; 126(Pt 16): 3713-23, 2013 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-23788427

13.

TIF1Î³ interferes with TGFß1/SMAD4 signaling to promote poor outcome in operable breast cancer patients.

Kassem, Loay; Deygas, Mathieu; Fattet, Laurent; Lopez, Jonathan; Goulvent, Thibaut; Lavergne, Emilie; Chabaud, Sylvie; Carrabin, Nicolas; Chopin, Nicolas; Bachelot, Thomas; Gillet, Germain; Treilleux, Isabelle; Rimokh, Ruth.

BMC Cancer; 15: 453, 2015 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-26040677

14.

Antagonistic regulation of EMT by TIF1Î³ and Smad4 in mammary epithelial cells.

Hesling, Cédric; Fattet, Laurent; Teyre, Guillaume; Jury, Delphine; Gonzalo, Philippe; Lopez, Jonathan; Vanbelle, Christophe; Morel, Anne-Pierre; Gillet, Germain; Mikaelian, Ivan; Rimokh, Ruth.

EMBO Rep; 12(7): 665-72, 2011 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-21597466

15.

A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor.

Aubol, Brandon E; Fattet, Laurent; Adams, Joseph A.

FEBS J; 288(2): 566-581, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32359191

16.

RREB1 Integrates TGF-ß and RAS Signals to Drive EMT.

Fattet, Laurent; Yang, Jing.

Dev Cell; 52(3): 259-260, 2020 02 10.

Artículo en Inglés | MEDLINE | ID: mdl-32049037

17.

Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex.

Fattet, Laurent; Jung, Hae-Yun; Matsumoto, Mike W; Aubol, Brandon E; Kumar, Aditya; Adams, Joseph A; Chen, Albert C; Sah, Robert L; Engler, Adam J; Pasquale, Elena B; Yang, Jing.

Dev Cell; 54(3): 302-316.e7, 2020 08 10.

Artículo en Inglés | MEDLINE | ID: mdl-32574556

18.

Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation.

Jung, Hae-Yun; Fattet, Laurent; Tsai, Jeff H; Kajimoto, Taketoshi; Chang, Qiang; Newton, Alexandra C; Yang, Jing.

Nat Cell Biol; 21(3): 359-371, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30804505

19.

Biomaterials to model and measure epithelial cancers.

Beri, Pranjali; Matte, Bibiana F; Fattet, Laurent; Kim, Daehwan; Yang, Jing; Engler, Adam J.

Nat Rev Mater; 3(11): 418-430, 2018 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-30416759

20.

Author Correction: Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation.