Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 39
Filtrar
Más filtros

Bases de datos
País/Región como asunto
Tipo del documento
Intervalo de año de publicación
1.
Radiographics ; 43(6): e220125, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-37141138

RESUMEN

Radiology is among the medical specialties that have made the fewest gains in closing the gap in underrepresented minorities and women. Diversity, equity, and inclusion (DEI) initiatives are important for promoting healthy learning environments for trainees, health equity for patients, and equitable career development opportunities for employees, all of which contribute to innovation in today's competitive health care environment. DEI committees can self-organize or form from institutional directives. These committees can implement impactful projects in multiple domains in education, recruitment and retention, department culture, and health equity research. This article describes the formation of a grassroots DEI committee, key initiatives and strategies, and structures for accountability. ©RSNA, 2023 Quiz questions for this article are available in the supplemental material.


Asunto(s)
Diversidad, Equidad e Inclusión , Radiología , Humanos , Femenino , Grupos Minoritarios , Aprendizaje
2.
Contact Dermatitis ; 2021 Feb 28.
Artículo en Inglés | MEDLINE | ID: mdl-33641162

RESUMEN

BACKGROUND: We present a case series of 10, atopic, African women who developed irritant contact dermatitis (ICD) from synthetic hair extensions. METHODS: Ten consecutive African female patients who presented with a pruritic cutaneous eruption on the neck over a period of 2 years are described. Patients underwent skin patch testing using both standard and hair commercial patch test panels and samples of their own hair extensions. Hair care products were not tested. RESULTS: All 10 patients used synthetic hair extensions. A strong history of atopy was documented for all the patients and examination was significant for eczematous, lichenified plaques at the location of contact with the free end of the hair extension. Patch test results yielded no relevant reactivity and a diagnosis of ICD was made for all patients. The lesions resolved completely on removal of the hair extensions and the use of topical steroids and emollients, dependent on eczema severity. CONCLUSIONS: Artificial hair extensions should be considered as a potential irritant, resulting in ICD. Patients with a history of atopy are at risk of developing ICD from synthetic hair extensions.

3.
Skin Pharmacol Physiol ; 34(4): 214-228, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33910205

RESUMEN

INTRODUCTION: The continuous availability of open micropores is crucial for a successful microneedle (MN) drug delivery strategy. However, micropore lifetime depends on intrinsic skin functional and anatomical characteristics, which vary significantly at different anatomical sites. OBJECTIVE: This pilot study explored if differences exist in micropore closure timeframes at 3 anatomical sites - upper arm, volar forearm, and abdomen. METHODS: Healthy subjects (n = 35) self-identifying as Asian (n = 9), Bi-/multiracial (n = 2), Black (n = 9), Latino (n = 6), and White (n = 9) completed the study. The upper arm, volar forearm, and abdomen were treated with MNs; skin impedance and transepidermal water loss (TEWL) were measured at baseline and post-MN to confirm micropore formation. Impedance was measured for 3 days to evaluate micropore lifetime. Measurements of L*, which quantifies the skin lightness/darkness, were made using a tristimulus colorimeter. Micropore lifetime was determined by comparing baseline and post-MN impedance measurements, and micropore closure half-life was predicted using mathematical modeling. RESULTS: Post-MN increase in TEWL and decrease in impedance were significant (p < 0.05), confirming successful micropore formation at all anatomical sites. When data were analyzed according to subject self-identified racial/ethnic groups, the mean micropore closure time at the abdomen (63.09 ± 13.13 h) was longer than the upper arm (60.34 ± 14.69 h) and volar forearm (58.29 ± 16.76 h). The predicted micropore closure half-life at anatomical sites was the abdomen (25.86 ± 14.96 h) ≈ upper arm (23.69 ± 13.67 h) > volar forearm (20.2 ± 11.99 h). Differences were not statistically significant between groups. Objective categorization by L* showed that the darker skin may be associated with longer micropore closure time at the abdomen site. CONCLUSIONS: Our results suggest that anatomical site of application may not be a source of significant variability in micropore closure time. These findings may help reduce the number of physiological parameters that need to be explicitly considered when developing drug products to support MN-assisted drug delivery strategies.


Asunto(s)
Abdomen/fisiología , Brazo/fisiología , Microinyecciones/métodos , Absorción Cutánea/fisiología , Adolescente , Adulto , Impedancia Eléctrica , Femenino , Humanos , Masculino , Persona de Mediana Edad , Proyectos Piloto , Grupos Raciales , Fenómenos Fisiológicos de la Piel , Adulto Joven
4.
Dermatol Surg ; 46(6): 735-741, 2020 06 01.
Artículo en Inglés | MEDLINE | ID: mdl-33555783

RESUMEN

BACKGROUND: Mohs micrographic surgery (MMS) is a cost-effective treatment for nonmelanoma skin cancer that bundles costs for surgical excision, tissue processing, and histopathological interpretation. A comprehensive MMS bundle would include all aspects of an episode of care (EOC), including costs of reconstruction, preoperative, and postoperative care. OBJECTIVE: To assess the feasibility of an alternative payment model for MMS and reconstruction. METHODS: Retrospective chart review and payment analysis for 848 consecutive patients with 1,056 tumors treated with MMS. Average Medicare payment of an EOC was compared with bundles based on specific repair types. RESULTS: The bundle for a flap/graft repair averaged $1,028.08 (confidence interval [CI] 95% $951.37-1,104.79), whereas the bundle for a linear closure (LC) averaged $585.07 (CI 95% $558.75-611.38). The average bundle including all repairs was $730.05 (CI 95% $692.31-767.79), which was statistically significant from both the flap/graft and LC bundles. CONCLUSION: Bundling surgical repairs with MMS based on an average payment does not represent the heterogeneity of the care provided and results in either underpayment or overpayment for a substantial portion of cases. Consequently, EOC payments bundling MMS and surgical repairs would inaccurately reimburse physicians for work completed. Current payment methodology allows for accurate payment for this already cost-effective therapy.


Asunto(s)
Medicare/economía , Cirugía de Mohs/economía , Paquetes de Atención al Paciente/economía , Neoplasias Cutáneas/economía , Neoplasias Cutáneas/cirugía , Centros Médicos Académicos/economía , Anciano , Anciano de 80 o más Años , Técnicas de Laboratorio Clínico/economía , Técnicas de Laboratorio Clínico/métodos , Análisis Costo-Beneficio , Procedimientos Quirúrgicos Dermatologicos/economía , Episodio de Atención , Estudios de Factibilidad , Femenino , Costos de la Atención en Salud , Costos de Hospital , Humanos , Masculino , Persona de Mediana Edad , Atención Perioperativa/economía , Procedimientos de Cirugía Plástica/economía , Estudios Retrospectivos , Piel/patología , Manejo de Especímenes/economía , Estados Unidos
5.
Dermatol Surg ; 46(6): 780-788, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-31567609

RESUMEN

BACKGROUND: The appearance and symptoms of scars can cause significant distress to patients. OBJECTIVE: To assess and compare efficacy of the 1,500-nm nonablative fractional laser (NAFL) and 10,600-nm ablative fractional laser (AFL) in reducing symptoms and improving the appearance of traumatic or surgical scars. MATERIALS AND METHODS: Single-center prospective, randomized, blinded, split-scar study was conducted on 100 patients with a scar obtained through trauma or surgery. Three treatments of NAFL or AFL were administered to each half of the scar at 4-week intervals. Scars were self-rated by the patient using the Patient and Observer Scar Assessment Scale and a satisfaction score and objectively evaluated by blinded dermatologists using the Manchester Scar Scale and visual analog scale. RESULTS: Blinded observers found no statistically significant difference in scar appearance. Patient rating showed improvement of scar appearance (p < .0001). Pain was worse after treatment with AFL (p = .0492). Overall, there was no statistically significant evidence of one laser being superior or inferior to the other for patient and blinded observer scores (p = .3173 and p = .2513, respectively). CONCLUSION: Scar treatment with AFL or NAFL is associated with high patient satisfaction. Objective evaluation of scars did not identify improvement in scar appearance.


Asunto(s)
Cicatriz/terapia , Terapia por Láser/instrumentación , Láseres de Gas/uso terapéutico , Láseres de Estado Sólido/uso terapéutico , Adolescente , Adulto , Anciano , Cicatriz/diagnóstico , Cicatriz/etiología , Femenino , Humanos , Terapia por Láser/efectos adversos , Terapia por Láser/métodos , Masculino , Persona de Mediana Edad , Medición de Resultados Informados por el Paciente , Satisfacción del Paciente , Estudios Prospectivos , Procedimientos Quirúrgicos Operativos/efectos adversos , Resultado del Tratamiento , Escala Visual Analógica , Heridas y Lesiones/complicaciones , Adulto Joven
6.
Transpl Int ; 32(12): 1268-1276, 2019 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-31502728

RESUMEN

Skin cancer is the most common malignancy affecting solid organ transplant recipients (SOTR), and SOTR experience increased skin cancer-associated morbidity and mortality. There are no formal multidisciplinary guidelines for skin cancer screening after transplant, and current practices are widely variable. We conducted three rounds of Delphi method surveys with a panel of 84 U.S. dermatologists and transplant physicians to establish skin cancer screening recommendations for SOTR. The transplant team should risk stratify SOTR for screening, and dermatologists should perform skin cancer screening by full-body skin examination. SOTR with a history of skin cancer should continue regular follow-up with dermatology for skin cancer surveillance. High-risk transplant patients include thoracic organ recipients, SOTR age 50 and above, and male SOTR. High-risk Caucasian patients should be screened within 2 years after transplant, all Caucasian, Asian, Hispanic, and high-risk African American patients should be screened within 5 years after transplant. No consensus was reached regarding screening for low-risk African American SOTR. We propose a standardized approach to skin cancer screening in SOTR based on multidisciplinary expert consensus. These guidelines prioritize and emphasize the need for screening for SOTR at greatest risk for skin cancer.


Asunto(s)
Técnica Delphi , Detección Precoz del Cáncer/métodos , Trasplante de Órganos/efectos adversos , Neoplasias Cutáneas/diagnóstico , Consenso , Femenino , Guías como Asunto , Humanos , Masculino , Medición de Riesgo , Neoplasias Cutáneas/epidemiología , Receptores de Trasplantes , Estados Unidos
7.
Dermatol Surg ; 45(2): 234-243, 2019 02.
Artículo en Inglés | MEDLINE | ID: mdl-30640776

RESUMEN

BACKGROUND: Despite extensive counseling, patients commonly call with postoperative concerns after Mohs micrographic surgery (MMS). OBJECTIVE: We sought to determine the incidence, reasons, and patient and surgical characteristics that lead to patient-initiated communication after MMS. MATERIALS AND METHODS: A retrospective chart review of 1,531 patients who underwent MMS during the observational period was conducted. Demographics and perioperative characteristics of patients who initiated communication were compared with a random sample of matched controls. RESULTS: Of the 1,531 patients who underwent MMS, 263 patients (17.2%) initiated 412 communication encounters within 90 days of surgery. Top reasons for patient-initiated communication included wound concerns, bleeding, and postoperative pain. Female patients and those with a larger surgical defect size (cm) were more likely to call postoperatively. Patients who underwent second intention healing, grafts, and interpolation flaps were more likely to initiate communication compared to patients repaired with a linear closure. CONCLUSION: This study identifies the incidence, reasons, and patient and surgical factors predictive of patient-initiated communication after MMS, which may allow for targeted improvements in postoperative counseling, ameliorating patient anxiety, augmenting patient satisfaction, and improved efficiency for the health care team.


Asunto(s)
Comunicación , Cirugía de Mohs/psicología , Complicaciones Posoperatorias/psicología , Neoplasias Cutáneas/psicología , Neoplasias Cutáneas/cirugía , Anciano , Femenino , Humanos , Iowa , Masculino , Persona de Mediana Edad , Medición de Resultados Informados por el Paciente , Atención Perioperativa , Periodo Posoperatorio , Estudios Retrospectivos
9.
Pediatr Dermatol ; 36(2): 262-264, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-30656724

RESUMEN

Subepidermal calcified nodules are lesions that primarily affect children and are most commonly located on the head. The current standard of treatment for these is surgical excision. However, surgical excision is not always possible and may not be cosmetically favorable. We describe the use of a CO2 laser as a successful treatment for a subepidermal calcified nodule of the finger.


Asunto(s)
Calcinosis/cirugía , Dedos/patología , Terapia por Láser/métodos , Láseres de Gas/uso terapéutico , Enfermedades de la Piel/cirugía , Adolescente , Calcinosis/patología , Femenino , Humanos , Enfermedades de la Piel/patología
10.
J Am Acad Dermatol ; 79(2): 337-341, 2018 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-29653209

RESUMEN

The American Academy of Dermatology has taken an active stance in addressing the lack of racial and ethnic diversity in the specialty. At the American Academy of Dermatology President's Conference on Diversity in Dermatology, which was held on August 5, 2017, key action items to increase the number of practicing board-certified dermatologists who are under-represented in medicine (UIM) were identified in 3 main areas. The action items include increasing the pipeline of UIM students applying to medical school, increasing UIM medical students' exposure to the field of dermatology and their level of interest in it, and increasing the number of UIM students recruited into dermatology residency programs.


Asunto(s)
Diversidad Cultural , Dermatología , Etnicidad , Grupos Raciales , Selección de Profesión , Dermatología/educación , Dermatología/estadística & datos numéricos , Femenino , Humanos , Internado y Residencia , Colaboración Intersectorial , Masculino , Mentores , Grupos Minoritarios , Sociedades Médicas , Estudiantes de Medicina/estadística & datos numéricos , Estados Unidos
15.
Am J Dermatopathol ; 37(10): 790-4, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-25747810

RESUMEN

IMPORTANCE: Posttransplant lymphoproliferative disorder (PTLD) is an uncommon complication after solid organ transplants and hematopoietic stem cell transplants. Extranodal involvement in PTLD can involve several organ systems, including the central nervous system, bone marrow, lungs, gastrointestinal tract, and skin. Isolated involvement of the skin without systemic involvement in PTLD is rare. Primary cutaneous PTLD is generally categorized as either cutaneous T-cell lymphomas or cutaneous B-cell lymphomas, with variable Epstein-Barr virus (EBV) positivity. Herein, we describe an exceedingly uncommon case of a polymorphic variant of primary cutaneous PTLD. OBSERVATIONS: A woman in her 30s, who received an EBV+ deceased donor kidney transplant, presented with a 2-week history of 2 indurated patches over the lower abdomen. A skin biopsy revealed an atypical lymphoid proliferation with immunohistochemical stains demonstrating a mixed population of both B and T cells that stained strongly positive for EBV-encoded RNA. A bone marrow biopsy and positron emission tomography/computed tomography were negative for systemic involvement. The patient was treated with immunosuppression reduction and rituximab infusions. CONCLUSIONS AND RELEVANCE: This case highlights a rare polymorphic variant of primary cutaneous EBV-associated PTLD and increases awareness of this uncommon posttransplant complication. Cutaneous PTLD is reviewed, therefore dermatologists are aware of this uncommon disorder.


Asunto(s)
Infecciones por Virus de Epstein-Barr/virología , Herpesvirus Humano 4/aislamiento & purificación , Trasplante de Riñón/efectos adversos , Trastornos Linfoproliferativos/virología , Enfermedades Cutáneas Virales/virología , Adulto , Biopsia , Infecciones por Virus de Epstein-Barr/tratamiento farmacológico , Infecciones por Virus de Epstein-Barr/inmunología , Infecciones por Virus de Epstein-Barr/patología , Femenino , Herpesvirus Humano 4/inmunología , Humanos , Inmunohistoquímica , Factores Inmunológicos/uso terapéutico , Inmunosupresores/efectos adversos , Trastornos Linfoproliferativos/tratamiento farmacológico , Trastornos Linfoproliferativos/inmunología , Trastornos Linfoproliferativos/patología , Tomografía de Emisión de Positrones , Rituximab/uso terapéutico , Enfermedades Cutáneas Virales/tratamiento farmacológico , Enfermedades Cutáneas Virales/inmunología , Enfermedades Cutáneas Virales/patología , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
18.
Am J Dermatopathol ; 35(4): e63-6, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-23221488

RESUMEN

Acute mucocutaneous methotrexate toxicity is not classically associated with prominent tissue eosinophilia. We present a case of acute methotrexate toxicity associated with pancytopenia and mucocutaneous erosion with interface dermatitis and numerous eosinophils. A 79-year-old male, with a history of psoriasis vulgaris on methotrexate therapy, presented with blisters of the oral mucosa, groin, sacrum, and extremities after daily consumption of methotrexate. Examination revealed blisters and erosions localized to psoriatic plaques, the perineum, and the oral mucosa. Laboratory evaluation demonstrated pancytopenia, megaloblastic anemia, and elevated liver function tests. A skin biopsy of an eroded plaque revealed psoriasiform epidermal hyperplasia with epidermal erosion, parakeratosis, and loss of the granular cell layer. There was an underlying band-like lymphoid infiltrate with interface dermatitis, dyskeratotic keratinocytes, and numerous eosinophils. Direct immunofluorescence studies were negative for the deposition of immunoreactants. Methotrexate was held, and the patient received leucovorin resulting in improvement of blood counts and cutaneous lesions. The histopathologic changes associated with acute mucocutaneous toxicity have been described as pauci-inflammatory erosions associated with dyskeratotic keratinocytes to interface dermatitis with necrotic keratinocytes and occasionally associated eosinophils. Although these changes are most often superimposed on psoriatic plaques, they have been reported to occur on normal skin. Therefore, the differential diagnosis may include lichen planus, a lichenoid drug eruption, or a fixed drug eruption, and given the presence of mucosal ulceration, incipient pemphigus vulgaris or paraneoplastic pemphigus vulgaris. This case illustrates that acute mucocutaneous methotrexate toxicity may be associated with both interface dermatitis and numerous eosinophils.


Asunto(s)
Fármacos Dermatológicos/efectos adversos , Erupciones por Medicamentos/etiología , Eosinofilia/inducido químicamente , Metotrexato/efectos adversos , Mucosa Bucal/efectos de los fármacos , Psoriasis/tratamiento farmacológico , Piel/efectos de los fármacos , Anciano , Biopsia , Diagnóstico Diferencial , Erupciones por Medicamentos/patología , Eosinofilia/patología , Humanos , Masculino , Microscopía Fluorescente , Mucosa Bucal/patología , Pancitopenia/inducido químicamente , Valor Predictivo de las Pruebas , Psoriasis/patología , Piel/patología
19.
Dermatol Clin ; 41(3): 481-489, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37236716

RESUMEN

Skin cancer is often associated with greater morbidity and mortality in skin of color patients because most medical literature and research on skin cancer to date has been predominantly focused on lighter skin types. It is crucial that dermatologic providers be able to recognize different presentations of skin cancer in skin of color patients to optimize the early detection of these tumors and ensure equitable outcomes. This article details the epidemiology, risk factors, clinical features, and disparities in the treatment of melanoma, squamous cell carcinoma, basal cell carcinoma, and mycosis fungoides subtype of cutaneous T-cell lymphoma in skin of color patients.


Asunto(s)
Carcinoma Basocelular , Micosis Fungoide , Neoplasias Cutáneas , Humanos , Pigmentación de la Piel , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/epidemiología , Neoplasias Cutáneas/terapia , Piel/patología , Micosis Fungoide/diagnóstico , Micosis Fungoide/epidemiología , Micosis Fungoide/terapia , Carcinoma Basocelular/diagnóstico , Carcinoma Basocelular/epidemiología , Carcinoma Basocelular/terapia
20.
Dermatol Clin ; 41(2): 359-369, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36933926

RESUMEN

Over the past few years, there have been concerted efforts to increase diversity in the field of dermatology. This has been achieved through the creation of Diversity, Equity, and Inclusion (DEI) initiatives in dermatology organizations that strive to provide resources and opportunities for trainees who are underrepresented in medicine. This article compiles the ongoing DEI initiatives in the American Academy of Dermatology, Women's Dermatologic Society, Association of Professors of Dermatology Society, Society for Investigative Dermatology, Skin of Color Society, American Society for Dermatologic Surgery, The Dermatology Section of the National Medical Association, and Society for Pediatric Dermatology.


Asunto(s)
Dermatología , Niño , Humanos , Femenino , Estados Unidos , Diversidad, Equidad e Inclusión , Sociedades Médicas
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA