Búsqueda | Portal de Búsqueda de la BVS España

1.

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

Assmann, Nadine; O'Brien, Katie L; Donnelly, Raymond P; Dyck, Lydia; Zaiatz-Bittencourt, Vanessa; Loftus, Róisín M; Heinrich, Paul; Oefner, Peter J; Lynch, Lydia; Gardiner, Clair M; Dettmer, Katja; Finlay, David K.

Nat Immunol; 18(11): 1197-1206, 2017 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-28920951

2.

N-myristoylation of AMPK controls T cell inflammatory function.

Finlay, David K.

Nat Immunol; 20(3): 252-254, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30718915

3.

Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions.

Ryan, Eimear K; Clutter, Christy; De Barra, Conor; Jenkins, Benjamin J; O'Shaughnessy, Simon; Ryan, Odhrán K; McKenna, Chloe; Heneghan, Helen M; Walsh, Fiona; Finlay, David K; Sinclair, Linda V; Jones, Nicholas; Leung, Daniel T; O'Shea, Donal; Hogan, Andrew E.

J Immunol; 212(11): 1706-1713, 2024 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-38619286

4.

De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells.

O'Brien, Katie L; Assmann, Nadine; O'Connor, Eimear; Keane, Cathal; Walls, Jessica; Choi, Chloe; Oefner, Peter J; Gardiner, Clair M; Dettmer, Katja; Finlay, David K.

Eur J Immunol; 51(1): 91-102, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32946110

5.

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.

O'Brien, Aisling; Loftus, Roisin M; Pisarska, Marta M; Tobin, Laura M; Bergin, Ronan; Wood, Nicole A W; Foley, Cathriona; Mat, Arimin; Tinley, Frances C; Bannan, Ciaran; Sommerville, Gary; Veerapen, Natacha; Besra, Gurdyal S; Sinclair, Linda V; Moynagh, Paul N; Lynch, Lydia; Finlay, David K; O'Shea, Donal; Hogan, Andrew E.

J Immunol; 202(12): 3404-3411, 2019 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-31076528

6.

Canonical TGF-ß Signaling Pathway Represses Human NK Cell Metabolism.

Zaiatz-Bittencourt, Vanessa; Finlay, David K; Gardiner, Clair M.

J Immunol; 200(12): 3934-3941, 2018 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-29720425

7.

Metabolic Reprogramming Supports IFN-Î³ Production by CD56bright NK Cells.

Keating, Sinéad E; Zaiatz-Bittencourt, Vanessa; Loftus, Roisín M; Keane, Ciara; Brennan, Kiva; Finlay, David K; Gardiner, Clair M.

J Immunol; 196(6): 2552-60, 2016 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-26873994

8.

Immunometabolism: Cellular Metabolism Turns Immune Regulator.

Loftus, Róisín M; Finlay, David K.

J Biol Chem; 291(1): 1-10, 2016 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-26534957

9.

Starved human T lymphocytes keep fighting.

Finlay, David K.

Eur J Immunol; 45(9): 2480-3, 2015 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-26256443

10.

mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.

Donnelly, Raymond P; Loftus, Róisín M; Keating, Sinéad E; Liou, Kevin T; Biron, Christine A; Gardiner, Clair M; Finlay, David K.

J Immunol; 193(9): 4477-84, 2014 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-25261477

11.

Metabolic regulation of natural killer cells.

Finlay, David K.

Biochem Soc Trans; 43(4): 758-62, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-26551725

12.

AMPKα1: a glucose sensor that controls CD8 T-cell memory.

Rolf, Julia; Zarrouk, Marouan; Finlay, David K; Foretz, Marc; Viollet, Benoit; Cantrell, Doreen A.

Eur J Immunol; 43(4): 889-96, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23310952

13.

Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans.

Scott, Barry; Day, Emily A; O'Brien, Katie L; Scanlan, John; Cromwell, Grace; Scannail, Aine Ni; McDonnell, Marie E; Finlay, David K; Lynch, Lydia.

Nat Metab; 6(4): 651-658, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38499765

14.

mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB.

Finlay, David K.

Biochem Soc Trans; 41(2): 681-6, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23514176

15.

Fatty acids are crucial to fuel NK cells upon acute retrovirus infection.

Schimmer, Simone; Mittermüller, Daniela; Werner, Tanja; Görs, Paul E; Meckelmann, Sven W; Finlay, David K; Dittmer, Ulf; Littwitz-Salomon, Elisabeth.

Front Immunol; 14: 1296355, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-38094304

16.

QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations.

Pelgrom, Leonard R; Davis, Gavin M; O'Shaughnessy, Simon; Wezenberg, Emilie J M; Van Kasteren, Sander I; Finlay, David K; Sinclair, Linda V.

Cell Rep; 42(8): 112828, 2023 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-37478011

17.

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.

Jenkins, Benjamin J; Blagih, Julianna; Ponce-Garcia, Fernando M; Canavan, Mary; Gudgeon, Nancy; Eastham, Simon; Hill, David; Hanlon, Megan M; Ma, Eric H; Bishop, Emma L; Rees, April; Cronin, James G; Jury, Elizabeth C; Dimeloe, Sarah K; Veale, Douglas J; Thornton, Catherine A; Vousden, Karen H; Finlay, David K; Fearon, Ursula; Jones, Gareth W; Sinclair, Linda V; Vincent, Emma E; Jones, Nicholas.

Cell Metab; 35(7): 1132-1146.e9, 2023 07 11.

Artículo en Inglés | MEDLINE | ID: mdl-37230079

18.

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells.

Finlay, David K; Kelly, April P; Clarke, Rosemary; Sinclair, Linda V; Deak, Maria; Alessi, Dario R; Cantrell, Doreen A.

J Immunol; 185(10): 5973-82, 2010 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-20944007

19.

The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing.

Cervantes-Silva, Mariana P; Carroll, Richard G; Wilk, Mieszko M; Moreira, Diana; Payet, Cloe A; O'Siorain, James R; Cox, Shannon L; Fagan, Lauren E; Klavina, Paula A; He, Yan; Drewinski, Tabea; McGinley, Alan; Buel, Sharleen M; Timmons, George A; Early, James O; Preston, Roger J S; Hurley, Jennifer M; Finlay, David K; Schoen, Ingmar; Javier Sánchez-García, F; Mills, Kingston H G; Curtis, Annie M.

Nat Commun; 13(1): 7217, 2022 12 05.

Artículo en Inglés | MEDLINE | ID: mdl-36470865

20.

Optimising NK cell metabolism to increase the efficacy of cancer immunotherapy.

Choi, Chloe; Finlay, David K.

Stem Cell Res Ther; 12(1): 320, 2021 06 05.

Artículo en Inglés | MEDLINE | ID: mdl-34090499

Portal de Búsqueda de la BVS España

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar:

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

N-myristoylation of AMPK controls T cell inflammatory function.

Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions.

De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells.

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.

Canonical TGF-ß Signaling Pathway Represses Human NK Cell Metabolism.

Metabolic Reprogramming Supports IFN-Î³ Production by CD56bright NK Cells.

Immunometabolism: Cellular Metabolism Turns Immune Regulator.

Starved human T lymphocytes keep fighting.

mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.

Metabolic regulation of natural killer cells.

AMPKα1: a glucose sensor that controls CD8 T-cell memory.

Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans.

mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB.

Fatty acids are crucial to fuel NK cells upon acute retrovirus infection.

QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations.

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells.

The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing.

Optimising NK cell metabolism to increase the efficacy of cancer immunotherapy.