Preferring fried dishes increases risk of benign breast disease, but not breast cancer.

BACKGROUND: Unhealthy diet and cooking method used may influence the risk of breast cancer (BC), but there is only limited evidence with regard to benign breast disease (BBD). The aim of this study was to assess a relationship between cooking technique, especially fried to boiled meals ratio in the diet, and the risk of BC and BBD in a group of Polish women. MATERIAL AND METHODS: A case-control study involving 34 BC cases, 81 BBD cases and 122 healthy controls was conducted between July 2007 and November 2011. All the women were asked about their nutritional habits, especially the way of preparing meat and fish dishes. Then the ratio of fried to boiled meals was calculated. RESULTS: High fried to boiled ratio was associated with increasing risk of BBD, but not BC. Women consuming fried dishes more often than boiled dishes had elevated risk of BBD: OR = 3.04 and OR = 3.65 for the second and the third tertile, respectively. Adjustment for the other confounders only slightly altered this relationship. CONCLUSION: Women who preferred frying as a cooking technique had increased risk of benign breast disease, but not breast cancer. There is a need of more precise investigation to confirm this association.

[Preoperative quality of life in women with pathological alteration in breast]. / Jakosc ycia kobiet ze zmianami patologicznymi piersi w okresie przygotowawczym do zabiegu chirurgicznego.

The aim of the study was to assess the similarities or differences in the psychosocial response to primary diagnosis of malicious or benign tumor in breast significantly influenced the quality of life in women in preoperative period. Health-related quality of life has been studied in the preoperative period in the group of 59 patients with malicious tumor and in the group of 130 women with benign tumor in comparison to 126 healthy women. Study was performed using self-administered questionnaire consists of The Rand Mental Health Inventory (three distress scores include depression, anxiety and loss of behavioral or emotional control; two well-being scores include general positive affect and emotional ties), COOP Charts (measuring nine dimensions of QOL), subscale focus on social support was used for the presented analysis; additionally questions concerning demographic and social characteristics of women as well as questions on illness behaviors have been involved. Statistical analysis was performed using multidimensional models of logistic regression. Results based on multidimensional logistic regression models showed higher risk of anxiety (OR=4,0; 95% CI=(1,8; 8,6)), depression(OR=3,0; 95% CI=(1,4; 6,2)) and distress (OR=2,5; 95% CI=(1,2; 5,3)) in women with malicious tumor in comparison to healthy women. Comparatively, higher risk of anxiety (OR=1,8; 95% CI=(1,0; 3,2)) and depression (OR=2,0; 95% CI=(1,2; 3,5)) among women with benign tumor in regard to healthy ones. Further examination of determinants of components of mental health among three analyzed group of women showed that among women with benign tumor higher risk of anxiety (OR=3,5; 95% CL=(1,2; 10,5)), depression (OR=3,2; 95% CI=(1,2;9,1)) and loss of behavioral or emotional control ((OR=4.3; 95% CI=(1,5;12,0)) as well as distress (OR=4,3; 95% CI=(1,5;13,0)) was related with considerable reduction of receiving support. Women with malicious tumor also indicated that slightly reduction of the received support was associated with higher risk of the loss of behavioral or emotional control (Isz=6,6; 95% PU=(1,4; 30,8)). Results confirmed that also diagnosis of benign tumor in breast is perceived as an event which significantly decreased quality of life in preoperative period. Interactions between medical staff - and patients with any change in breast should based on good verbal communication, giving information which help understanding by patients all aspects of diagnosis and expected treatment.

Job stress and mortality in older age.

OBJECTIVES: This paper aims to assess the relationship between the determinants of the psychosocial work environment, as expressed in terms of JDC or ERI models, and all-cause mortality in older individuals. MATERIALS AND METHODS: The baseline study was conducted on a cohort comprising a random sample of 65-year-old community-dwelling citizens of Kraków, Poland. All of the 727 participants (410 women, 317 men) were interviewed in their households in the period between 2001 and 2003; a structured questionnaire was used regarding their occupational activity history, which included indexes measuring particular dimensions of their psychosocial work environment based on Karasek's Job Demand-Control model and Siegrist's Effort-Reward Imbalance model, as well as health-related quality of life and demographic data. Mortality was ascertained by monitoring City Vital Records for 7 years. Analyses were conducted separately for men and women, with the multivariate Cox proportional hazard model. RESULTS: During a 7-year follow-up period, 59 participants (8.1%) died, including 21 women (5.1% of total women) and 38 men (12%) (p < 0.05). Significant differences in the number of deaths occurred regarding disproportion between physical demands and control in men: those with low physical demands and low control died three times more often than those with high control, regardless of the level of demands. The multivariate Cox proportional hazard model showed that significantly higher risk of death was observed only in men with low physical demands and low control, compared to those with low physical demands and high control (Exp(B) = 4.65, 95% CI: 1.64-13.2). CONCLUSIONS: Observed differences in mortality patterns are similar to the patterns of relationships observed in health-related quality of life (HRQoL) level at the beginning of old age; however, the relationship between efforts and rewards or demands and control and mortality was not fully confirmed.

The role of different predictors in 20-year mortality among Krakow older citizens.

BACKGROUND: The aim of this study was to assess the change in the predictive ability of gender-related 20-year all-cause mortality in community-dwelling older people. METHODS: The baseline investigation was conducted in 1986-1987 and survival of 2472 subjects aged 65 years and older was followed up for 20 years. The associations of socioeconomic conditions and health measures with mortality were assessed using Cox hazard model with time-dependent covariates. RESULTS: Our study confirmed that higher education and being employed during the baseline were protective factors in males, but not among females. Healthy lifestyle was a predictive factor for all-cause mortality for both men and women and its predictive value was strong over the whole observation period. The study showed that poor self-rated health (SRH) was a valid predictor of mortality in elderly women, but not in men, and the effect of the length of follow-up on mortality was not observed. Overall, different sets of all-cause mortality predictors were found for men and women. For men the role of socioeconomic status factors was confirmed as well as healthy lifestyle and presence of chronic conditions, especially coronary heart disease (CHD) and asthma. For women the most important predictors were lifestyle factors and the feeling of life-weariness as well as SRH and diabetes mellitus present during the baseline study. CONCLUSIONS: The impact of most of the examined factors on mortality was found to be stable over the twenty years of observation with the exception of the self-reported CHD, whose predictive value decreased over time.