[Topical cyclosporine in the treatment of ocular actinic prurigo]. / Ciclosporina tópica como tratamiento del prúrigo actínico ocular.

CASE REPORT: A 14-year-old girl from Peru suffered severe limbitis and conjunctivitis. She also presented with clinical skin features diagnosed as actinic prurigo (AP). Her symptoms were successfully controlled with sustained topical therapy of 2% Cyclosporine A. DISCUSSION: AP is an idiopathic photodermatosis that affects mainly the hispanic population of Latin America. There are ocular signs of severe limbitis and conjunctivitis (like atopic keratoconjunctivitis) in 45% of cases. Literature on the subject is very limited and currently topical cyclosporine seems to be the best therapy available.

[Bilateral carotid occlusion in young woman. Clinical and hemodynamic ocular results]. / Oclusión carotídea en mujer joven. Consecuencias oculares clínicas y hemodinámicas.

CASE REPORT: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. DISCUSSION: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient's risk of stroke and death.

[Siderosis bulbi. Clinical presentation of a case of three years from onset]. / Siderosis bulbi. Presentación clínica de un caso de tres años de evolución.

CASE REPORT: The clinical and functional characteristics of a 30 years-old patient with three years-evolution siderosis bulbi are described in this paper, as well as the treatment using phacoemulsification and vitrectomy for the elimination of the metallic remains. DISCUSSION: In spite of the fact that the majority of the intraocular foreign bodies (IOFB) have a dangerous immediate effect, in cases of small, local bodies and with little visual deterioration, observation is possible. Nevertheless, with time, the iron settles on the pigmented epithelium of the retina, producing changes at macula and peripheral level, which are responsible for the gradual loss of vision. The surgical removal of the IOFB can stop the progression of this pathology.

Siderosis bulbi. Presentación clínica de un caso de tres años de evolución / Siderosis bulbi. Clinical presentation of a case of three years from onset

Caso clínico: Se presentan las características clínicas y funcionales de un paciente de 30 años con siderosis bulbi de tres años de evolución, y el tratamiento mediante facoemulsificación y vitrectomía para la eliminación de los restos metálicos. Discusión: A pesar de que la mayoría de los cuerpos extraños intraoculares (CEIO) tienen un efecto deletéreo inmediato, en casos de cuerpos pequeños, localizados y con poca afectación visual, es posible su observación. Sin embargo, con el tiempo, el hierro se deposita en el epitelio pigmentado de la retina, produciendo cambios a nivel macular y periférico responsables de pérdida progresiva de visión. La cirugía de extracción del CEIO puede frenar la progresión de esta dolencia(AU)

Case report: The clinical and functional characteristics of a 30 years-old patient with three years-evolution siderosis bulbi are described in this paper, as well as the treatment using phacoemulsification and vitrectomy for the elimination of the metallic remains. Discussion: In spite of the fact that the majority of the intraocular foreign bodies (IOFB) have a dangerous immediate effect, in cases of small, local bodies and with little visual deterioration, observation is possible. Nevertheless, with time, the iron settles on the pigmented epithelium of the retina, producing changes at macula and peripheral level, which are responsible for the gradual loss of vision. The surgical removal of the IOFB can stop the progression of this pathology(AU)

Ciclosporina tópica como tratamiento del prúrigo actínico ocular / Topical cyclosporine in the treatment of ocular actinic prurigo

Caso clínico: Presentamos el caso de una mujer de 14 años latinoamericana, con una limbo-conjuntivitis severa. Habia sido diagnosticada de prúrigo actínico (PA) por el dermatólogo. Con el diagnóstico de PA ocular se inició tratamiento con colirio de ciclosporina A 2% con buena respuesta. Discusión: El PA es una fotodermatosis idiopática que afecta principalmente a la población mestiza de Latino América. Los ojos se ven afectados en el 45% de los casos, como una limbo-conjuntivitis severa semejante a la atópica. A pesar de la escasa bibliografía existente, la ciclosporina tópica representa la mejor alternativa en el tratamiento del PA ocular

Case report: A 14-year-old girl from Peru suffered severe limbitis and conjunctivitis. She also presented with clinical skin features diagnosed as actinic prurigo (AP). Her symptoms were successfully controlled with sustained topical therapy of 2% Cyclosporine A. Discussion: AP is an idiopathic photodermatosis that affects mainly the hispanic population of Latin America. There are ocular signs of severe limbitis and conjunctivitis (like atopic keratoconjunctivitis) in 45% of cases. Literature on the subject is very limited and currently topical cyclosporine seems to be the best therapy available

Oclusión carotídea en mujer joven. Consecuencias oculares clínicas y hemodinámicas / Bilateral carotid occlusion in young woman. Clinical and hemodynamic ocular results

Caso clínico: Describimos el caso de una mujer de 44 años, fumadora de 60 cig./día y con antecedentes de hipertiroidismo. Presentó un síndrome de isquemia ocular en ambos ojos (AO) por oclusión de carótidas internas que originó un flujo retrógrado en ambas arterias oftálmicas, produciendo un fenómeno de robo caracterizado por un shunt a los circuitos intracraneales de baja resistencia y una reducción en el aporte sanguíneo a los ojos. Discusión: Los pacientes jóvenes con obstrucción carotídea bilateral severa tienen mayor riesgo de desarrollar un síndrome de isquemia ocular, mientras este flujo retrógrado parece reducir su riesgo de infarto cerebral o muerte (AU)

Case report: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. Discussion: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient’s risk of stroke and death (AU)