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Rev Cubana Med Trop ; 58(3): 248-53, 2006.
Artículo en Español | MEDLINE | ID: mdl-23424794

RESUMEN

A prospective and descriptive study of 20 patients infected with HIV and admitted to "Pedro Kouri" Institute of Tropical Disease after a diagnosis of lymphoma was conducted. They were all evaluated at the onset of diagnosis by a thorough medical record exam and supportive studies such as complete blood count, globular sedimentation speed, CD4+ count, lactic acid dehydrogenase, HIV viral load, cytology and biopsy. Of this number, 85% presented with CD4+ count under 350 cell/mm3 at the time of diagnosis; however, only 55% showed viral loads exceeding 50,000 copies/mL. The predominant histological subtype was large diffuse cells and the most frequent location was the extrapulmonary site in 70% of cases. It called our attention that high levels of lactic acid dehydrogenase and extrapulmonary location of tumors were related. Statistically significant association was found (p < 0.05) between immunosuppresion condition of the patients given by CD4+ count below 350 cell/mm3 and advanced staging of the tumoral disease (stages III and IV).


Asunto(s)
Linfoma Relacionado con SIDA/epidemiología , Academias e Institutos , Adulto , Biomarcadores de Tumor/sangre , Sedimentación Sanguínea , Recuento de Linfocito CD4 , Cuba/epidemiología , Etnicidad/estadística & datos numéricos , Femenino , Humanos , Huésped Inmunocomprometido , L-Lactato Deshidrogenasa/sangre , Linfoma Relacionado con SIDA/sangre , Linfoma Relacionado con SIDA/inmunología , Linfoma Relacionado con SIDA/patología , Masculino , Estadificación de Neoplasias , Estudios Prospectivos , Factores de Riesgo , Carga Viral , Viremia/epidemiología , Adulto Joven
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