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1.

Deubiquitinase-targeting chimeras for targeted protein stabilization.

Henning, Nathaniel J; Boike, Lydia; Spradlin, Jessica N; Ward, Carl C; Liu, Gang; Zhang, Erika; Belcher, Bridget P; Brittain, Scott M; Hesse, Matthew J; Dovala, Dustin; McGregor, Lynn M; Valdez Misiolek, Rachel; Plasschaert, Lindsey W; Rowlands, David J; Wang, Feng; Frank, Andreas O; Fuller, Daniel; Estes, Abigail R; Randal, Katelyn L; Panidapu, Anoohya; McKenna, Jeffrey M; Tallarico, John A; Schirle, Markus; Nomura, Daniel K.

Nat Chem Biol; 18(4): 412-421, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35210618

2.

Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.

Bussiere, Dirksen E; Xie, Lili; Srinivas, Honnappa; Shu, Wei; Burke, Ashley; Be, Celine; Zhao, Junping; Godbole, Adarsh; King, Dan; Karki, Rajeshri G; Hornak, Viktor; Xu, Fangmin; Cobb, Jennifer; Carte, Nathalie; Frank, Andreas O; Frommlet, Alexandra; Graff, Patrick; Knapp, Mark; Fazal, Aleem; Okram, Barun; Jiang, Songchun; Michellys, Pierre-Yves; Beckwith, Rohan; Voshol, Hans; Wiesmann, Christian; Solomon, Jonathan M; Paulk, Joshiawa.

Nat Chem Biol; 16(3): 361, 2020 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-31942047

3.

Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.

Bussiere, Dirksen E; Xie, Lili; Srinivas, Honnappa; Shu, Wei; Burke, Ashley; Be, Celine; Zhao, Junping; Godbole, Adarsh; King, Dan; Karki, Rajeshri G; Hornak, Viktor; Xu, Fangmin; Cobb, Jennifer; Carte, Nathalie; Frank, Andreas O; Frommlet, Alexandra; Graff, Patrick; Knapp, Mark; Fazal, Aleem; Okram, Barun; Jiang, Songchun; Michellys, Pierre-Yves; Beckwith, Rohan; Voshol, Hans; Wiesmann, Christian; Solomon, Jonathan M; Paulk, Joshiawa.

Nat Chem Biol; 16(1): 15-23, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31819272

4.

Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.

Han, Wooseok; Ma, Xiaolei; Balibar, Carl J; Baxter Rath, Christopher M; Benton, Bret; Bermingham, Alun; Casey, Fergal; Chie-Leon, Barbara; Cho, Min-Kyu; Frank, Andreas O; Frommlet, Alexandra; Ho, Chi-Min; Lee, Patrick S; Li, Min; Lingel, Andreas; Ma, Sylvia; Merritt, Hanne; Ornelas, Elizabeth; De Pascale, Gianfranco; Prathapam, Ramadevi; Prosen, Katherine R; Rasper, Dita; Ruzin, Alexey; Sawyer, William S; Shaul, Jacob; Shen, Xiaoyu; Shia, Steven; Steffek, Micah; Subramanian, Sharadha; Vo, Jason; Wang, Feng; Wartchow, Charles; Uehara, Tsuyoshi.

J Am Chem Soc; 142(9): 4445-4455, 2020 03 04.

Artículo en Inglés | MEDLINE | ID: mdl-32064871

5.

First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein.

Proudfoot, Andrew; Hyrina, Anastasia; Holdorf, Meghan; Frank, Andreas O; Bussiere, Dirksen.

J Virol; 93(13)2019 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-31019049

6.

Comprehensive and High-Throughput Exploration of Chemical Space Using Broadband ¹⁹ FâNMR-Based Screening.

Lingel, Andreas; Vulpetti, Anna; Reinsperger, Tony; Proudfoot, Andrew; Denay, Regis; Frommlet, Alexandra; Henry, Christelle; Hommel, Ulrich; Gossert, Alvar D; Luy, Burkhard; Frank, Andreas O.

Angew Chem Int Ed Engl; 59(35): 14809-14817, 2020 08 24.

Artículo en Inglés | MEDLINE | ID: mdl-32363632

7.

Facilitating unambiguous NMR assignments and enabling higher probe density through selective labeling of all methyl containing amino acids.

Proudfoot, Andrew; Frank, Andreas O; Ruggiu, Fiorella; Mamo, Mulugeta; Lingel, Andreas.

J Biomol NMR; 65(1): 15-27, 2016 05.

Artículo en Inglés | MEDLINE | ID: mdl-27130242

8.

Direct prediction of residual dipolar couplings of small molecules in a stretched gel by stochastic molecular dynamics simulations.

Frank, Andreas O; Freudenberger, J Christoph; Shaytan, Alexey K; Kessler, Horst; Luy, Burkhard.

Magn Reson Chem; 53(3): 213-7, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25612077

9.

Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure.

Marelli, Udaya Kiran; Frank, Andreas O; Wahl, Bernhard; La Pietra, Valeria; Novellino, Ettore; Marinelli, Luciana; Herdtweck, Eberhardt; Groll, Michael; Kessler, Horst.

Chemistry; 20(44): 14201-6, 2014 Oct 27.

Artículo en Inglés | MEDLINE | ID: mdl-25251673

10.

Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein.

Feldkamp, Michael D; Frank, Andreas O; Kennedy, J Phillip; Patrone, James D; Vangamudi, Bhavatarini; Waterson, Alex G; Fesik, Stephen W; Chazin, Walter J.

Biochemistry; 52(37): 6515-24, 2013 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-23962067

11.

Fragment-based drug discovery using NMR spectroscopy.

Harner, Mary J; Frank, Andreas O; Fesik, Stephen W.

J Biomol NMR; 56(2): 65-75, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23686385

12.

Correction to "Rational Chemical Design of Molecular Glue Degraders".

Toriki, Ethan S; Papatzimas, James W; Nishikawa, Kaila; Dovala, Dustin; Frank, Andreas O; Hesse, Matthew J; Dankova, Daniela; Song, Jae-Geun; Bruce-Smythe, Megan; Struble, Heidi; Garcia, Francisco J; Brittain, Scott M; Kile, Andrew C; McGregor, Lynn M; McKenna, Jeffrey M; Tallarico, John A; Schirle, Markus; Nomura, Daniel K.

ACS Cent Sci; 9(8): 1702, 2023 Aug 23.

Artículo en Inglés | MEDLINE | ID: mdl-37637749

13.

Rational Chemical Design of Molecular Glue Degraders.

Toriki, Ethan S; Papatzimas, James W; Nishikawa, Kaila; Dovala, Dustin; Frank, Andreas O; Hesse, Matthew J; Dankova, Daniela; Song, Jae-Geun; Bruce-Smythe, Megan; Struble, Heidi; Garcia, Francisco J; Brittain, Scott M; Kile, Andrew C; McGregor, Lynn M; McKenna, Jeffrey M; Tallarico, John A; Schirle, Markus; Nomura, Daniel K.

ACS Cent Sci; 9(5): 915-926, 2023 May 24.

Artículo en Inglés | MEDLINE | ID: mdl-37252349

14.

Intestinal permeability of cyclic peptides: common key backbone motifs identified.

Beck, Johannes G; Chatterjee, Jayanta; Laufer, Burkhardt; Kiran, Marelli Udaya; Frank, Andreas O; Neubauer, Stefanie; Ovadia, Oded; Greenberg, Sarit; Gilon, Chaim; Hoffman, Amnon; Kessler, Horst.

J Am Chem Soc; 134(29): 12125-33, 2012 Jul 25.

Artículo en Inglés | MEDLINE | ID: mdl-22737969

15.

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.

Souza-Fagundes, Elaine M; Frank, Andreas O; Feldkamp, Michael D; Dorset, Daniel C; Chazin, Walter J; Rossanese, Olivia W; Olejniczak, Edward T; Fesik, Stephen W.

Anal Biochem; 421(2): 742-9, 2012 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-22197419

16.

The impact of amino acid side chain mutations in conformational design of peptides and proteins.

Laufer, Burkhardt; Frank, Andreas O; Chatterjee, Jayanta; Neubauer, Thomas; Mas-Moruno, Carles; Kummerlöwe, Grit; Kessler, Horst.

Chemistry; 16(18): 5385-90, 2010 May 10.

Artículo en Inglés | MEDLINE | ID: mdl-20358563

17.

A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses.

Kane, Joshua R; Fong, Susan; Shaul, Jacob; Frommlet, Alexandra; Frank, Andreas O; Knapp, Mark; Bussiere, Dirksen E; Kim, Peter; Ornelas, Elizabeth; Cuellar, Carlos; Hyrina, Anastasia; Abend, Johanna R; Wartchow, Charles A.

Elife; 92020 01 21.

Artículo en Inglés | MEDLINE | ID: mdl-31960795

18.

Biophysics: the sweetest candy for the virus.

Frank, Andreas O; Kessler, Horst.

Nature; 452(7189): 822-3, 2008 Apr 17.

Artículo en Inglés | MEDLINE | ID: mdl-18421340

19.

Selective Methyl Labeling of Proteins: Enabling Structural and Mechanistic Studies As Well As Drug Discovery Applications by Solution-State NMR.

Proudfoot, Andrew; Frank, Andreas O; Frommlet, Alexandra; Lingel, Andreas.

Methods Enzymol; 614: 1-36, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30611421

20.

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity.

Demmer, Oliver; Frank, Andreas O; Hagn, Franz; Schottelius, Margret; Marinelli, Luciana; Cosconati, Sandro; Brack-Werner, Ruth; Kremb, Stephan; Wester, Hans-Jürgen; Kessler, Horst.

Angew Chem Int Ed Engl; 51(32): 8110-3, 2012 Aug 06.

Artículo en Inglés | MEDLINE | ID: mdl-22760863

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