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1.
Plasma 6ß-hydroxycortisol to cortisol ratio as a less invasive cytochrome P450 3A phenotyping method.
Br J Clin Pharmacol;
90(4): 1016-1026, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38102865
2.
Calculation of Human Melatonin Partial Metabolic Clearance in Healthy Adult Volunteers for Investigation of a Novel in Vivo CYP1A2 Phenotyping Method: A Pilot Study.
Biol Pharm Bull;
46(5): 736-740, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37121701
3.
Conserved lysine residues in decorin binding proteins of Borrelia garinii are critical in adhesion to human brain microvascular endothelial cells.
Mol Microbiol;
115(6): 1395-1409, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33512032
4.
Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules.
Mol Pharm;
19(8): 2754-2764, 2022 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35766901
5.
In Vitro-In Vivo Correlation of Blood-Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.
Pharm Res;
39(7): 1575-1586, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35288803
6.
Development and Validation of an LC-MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin.
Chem Pharm Bull (Tokyo);
70(5): 375-382, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35491194
7.
Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer.
Int J Mol Sci;
23(1)2022 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35008999
8.
Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure.
J Biol Chem;
295(52): 18614-18624, 2020 12 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33127645
9.
Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1-transgenic mice.
Glia;
69(8): 1987-2005, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33934399
10.
Development, Characterization and Potential Applications of a Multicellular Spheroidal Human Blood-Brain Barrier Model Integrating Three Conditionally Immortalized Cell Lines.
Biol Pharm Bull;
44(7): 984-991, 2021 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33896887
11.
Interstitial flow regulates in vitro three-dimensional self-organized brain micro-vessels.
Biochem Biophys Res Commun;
533(3): 600-606, 2020 12 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32988592
12.
JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function.
J Pharmacol Sci;
144(1): 16-22, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32653341
13.
Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood-Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/ciß.
Mol Pharm;
16(5): 2162-2171, 2019 05 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30983357
14.
A Human Immortalized Cell-Based Blood-Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug-Brain Permeability Studies.
Mol Pharm;
16(11): 4461-4471, 2019 11 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31573814
15.
Polyamines stimulate the CHSY1 synthesis through the unfolding of the RNA G-quadruplex at the 5'-untraslated region.
Biochem J;
475(23): 3797-3812, 2018 12 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30401686
16.
In Vivo Introduction of mRNA Encapsulated in Lipid Nanoparticles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration.
Mol Pharm;
15(5): 2060-2067, 2018 05 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29638135
17.
Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation.
Bioorg Med Chem Lett;
28(23-24): 3708-3711, 2018 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30389287
18.
Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies.
J Pharmacol Sci;
137(4): 350-358, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30150146
19.
Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.
Biol Pharm Bull;
41(5): 697-706, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29709907
20.
Development of a New Conditionally Immortalized Human Liver Sinusoidal Endothelial Cells.
Biol Pharm Bull;
41(3): 440-444, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29491221